Histidine is decarboxylated to histamine

Stable Identifier
R-HSA-977301
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Decarboxylation of L-Histidine happens analogously to other decarboxylations of amino acids. It uses the cofactor pyridoxal phosphate and is catalyzed by histidine decarboxylase (Mamune-Sato et al, 1992).

Literature References
PubMed ID Title Journal Year
1425659 Functional analysis of alternatively spliced transcripts of the human histidine decarboxylase gene and its expression in human tissues and basophilic leukemia cells

Mamune-Sato, R, Yamauchi, K, Tanno, Y, Ohkawara, Y, Ohtsu, H, Katayose, D, Maeyama, K, Watanabe, T, Shibahara, S, Takishima, T

Eur J Biochem 1992
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
histidine decarboxylase activity of PXLP-K305-HDC dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created