Reactome | KCNC1 [plasma membrane]

KCNC1 [plasma membrane]

Stable Identifier

R-HSA-977463

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Potassium voltage-gated channel subfamily C member 1, KCNC1_HUMAN

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Potassium Channels (Homo sapiens)
  - Voltage gated Potassium channels (Homo sapiens)
    - Activation of voltage gated Potassium channels (Homo sapiens)
      - Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
        
        Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
        
        Kv3 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
        
        KCNC1 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P48547 KCNC1

Gene Names

KCNC1

Chain

chain:1-511

Reference Genes

BioGPS Gene:3746 KCNC1

COSMIC (genes):KCNC1 KCNC1

CTD Gene:3746 KCNC1

dbSNP Gene:3746 KCNC1

ENSEMBL:ENSG00000129159 KCNC1

ENSEMBL_homo_sapiens_GENE:ENSG00000129159.9 KCNC1

HGNC:6233 KCNC1

KEGG Gene (Homo sapiens):3746 KCNC1

Monarch:3746 KCNC1

NCBI Gene:3746 KCNC1

OMIM:176258 KCNC1

UCSC:P48547 KCNC1

Reference Transcript

Other Identifiers

11728567_at

11737520_a_at

16722532

208477_PM_at

208477_at

230547_PM_at

230547_at

32322_at

3322522

3322523

3322524

3322525

3322526

3322527

3322543

3322544

3322545

3322546

3322547

3322548

3322549

3322550

3322551

3322552

3322553

3322554

3322555

3322572

3322600

3322602

3322604

3746

43443_at

7938738

A_14_P112745

A_23_P203439

A_24_P275199

A_24_P38810

A_33_P3237379

GE58767

GE80464

GE853606

GE85766

GO:0005215

GO:0005216

GO:0005249

GO:0005251

GO:0005267

GO:0005515

GO:0005886

GO:0006811

GO:0006813

GO:0008076

GO:0008092

GO:0009636

GO:0009642

GO:0009986

GO:0010996

GO:0014075

GO:0016020

GO:0019894

GO:0021549

GO:0021554

GO:0021759

GO:0022038

GO:0030424

GO:0030425

GO:0030673

GO:0032589

GO:0032590

GO:0032809

GO:0034220

GO:0034702

GO:0034765

GO:0034767

GO:0035864

GO:0042734

GO:0042995

GO:0043025

GO:0043679

GO:0044305

GO:0044325

GO:0045202

GO:0045211

GO:0048856

GO:0051260

GO:0051262

GO:0055085

GO:0065003

GO:0071466

GO:0071774

GO:0071805

GO:0099505

GO:0099508

GO:1901379

GO:1901381

GO:1990089

HMNXSV003018817

HMNXSV003035562

Hs.23539.0.A1_3p_at

ILMN_1752412

ILMN_1869243

ILMN_1911012

PH_hs_0002069

PH_hs_0010745

TC11000233.hg

TC11002582.hg

TC11002583.hg

g4826785_3p_at

Participates

as a member of

Kv3 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)

Inferred To

Shawl [plasma membrane] (Drosophila melanogaster)

Kcnc1 [plasma membrane] (Mus musculus)

Kcnc1 [plasma membrane] (Rattus norvegicus)

Shaw [plasma membrane] (Drosophila melanogaster)

KCNC1 [plasma membrane] (Bos taurus)

KCNC1 [plasma membrane] (Canis familiaris)

KCNC1 [plasma membrane] (Gallus gallus)

KCNC1 [plasma membrane] (Sus scrofa)

Homologues of KCNC1 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001106212.1, NP_004967.1

Guide to Pharmacology - Targets

548

OpenTargets

ENSG00000129159

GeneCards

P48547

HPA

ENSG00000129159-KCNC1

ZINC target

P48547

Ensembl

ENST00000640909, ENST00000265969, ENSG00000129159, ENSP00000491644, ENSP00000368785, ENST00000379472, ENSP00000265969

PRO

P48547

Pharos - Targets

P48547

ZINC - Predictions - Purchasable

KCNC1_HUMAN

Orphanet

23484

PDB

7PHK, 7PQU, 7PQT, 7PHL, 7PHI, 7PHH