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Cell surface:C3b [plasma membrane]
Stable Identifier
R-HSA-981542
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Activation of C3 and C5 (Homo sapiens)
Activation of C5 (Homo sapiens)
C5 convertases [plasma membrane] (Homo sapiens)
C4b:C2a:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cleavage of C3 by C3 convertases (Homo sapiens)
C3 convertases [plasma membrane] (Homo sapiens)
C4b:C2a:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Formation of classic pathway C5 convertase (Homo sapiens)
C4b:C2a:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Alternative complement activation (Homo sapiens)
C3b binds to cell surface (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Factor B binds to surface-associated C3b (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b:CFB [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Factor D cleaves C3b-bound Factor B (Homo sapiens)
Cell surface:C3b:CFB [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Regulation of Complement cascade (Homo sapiens)
C3 convertases spontaneously dissociate (Homo sapiens)
C3 convertases [plasma membrane] (Homo sapiens)
C4b:C2a:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
CD46 binds C3b (Homo sapiens)
CD46:Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
CFHR dimers bind C3b (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b:CFHR dimers [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Complement factor I binds to MCP, CR1:C4b, C3b (Homo sapiens)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Homo sapiens)
CD46:Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Homo sapiens)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Homo sapiens)
CD46:Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Complement factor I binds to membrane-associated Factor H:C3b (Homo sapiens)
CFI:CFH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:FH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:FH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Factor H binds to membrane-associated C3b (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:FH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Factor H displaces Bb (Homo sapiens)
Cell surface:FH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Factor I inactivates Factor H-boundC3b (Homo sapiens)
CFI:CFH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:FH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Factor I inactivates MCP/CR1-bound C4b/C3b (Homo sapiens)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Homo sapiens)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Homo sapiens)
CD46:Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b [plasma membrane] (Homo sapiens)
Participants
components
C3b [extracellular region]
(Homo sapiens)
Cell surface [plasma membrane]
Participates
as a component of
Cell surface:C3b:CFHR dimers [plasma membrane] (Homo sapiens)
CD46:Cell surface:C3b [plasma membrane] (Homo sapiens)
Cell surface:FH,FHR3:C3b [plasma membrane] (Homo sapiens)
Cell surface:C3b:CFB [plasma membrane] (Homo sapiens)
C4b:C2a:C3b [plasma membrane] (Homo sapiens)
as an input of
CFHR dimers bind C3b (Homo sapiens)
CD46 binds C3b (Homo sapiens)
Factor H binds to membrane-associated C3b (Homo sapiens)
Formation of classic pathway C5 convertase (Homo sapiens)
Factor B binds to surface-associated C3b (Homo sapiens)
as an output of
C3b binds to cell surface (Homo sapiens)
Inferred To
Cell surface:C3b [plasma membrane]
(Bos taurus)
Cell surface:C3b [plasma membrane]
(Canis familiaris)
Cell surface:C3b [plasma membrane]
(Danio rerio)
Cell surface:C3b [plasma membrane]
(Gallus gallus)
Cell surface:C3b [plasma membrane]
(Mus musculus)
Cell surface:C3b [plasma membrane]
(Rattus norvegicus)
Cell surface:C3b [plasma membrane]
(Sus scrofa)
Cell surface:C3b [plasma membrane]
(Xenopus tropicalis)
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