Reactome | DPPA2 [nucleoplasm]

DPPA2 [nucleoplasm]

Stable Identifier

R-HSA-9816401

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Developmental pluripotency-associated protein 2, DPPA2_HUMAN

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External Reference Information

External Reference

UniProt:Q7Z7J5 DPPA2

Gene Names

DPPA2, PESCRG1

Chain

chain:1-298

Reference Genes

BioGPS Gene:151871 DPPA2

COSMIC (genes):DPPA2 DPPA2

CTD Gene:151871 DPPA2

dbSNP Gene:151871 DPPA2

ENSEMBL:ENSG00000163530 DPPA2

HGNC:19197 DPPA2

Monarch:151871 DPPA2

NCBI Gene:151871 DPPA2

OMIM:614445 DPPA2

UCSC:Q7Z7J5 DPPA2

Reference Transcript

Other Identifiers

11726534_at

151871

16957254

240301_PM_at

240301_at

2688167

2688168

2688169

2688170

2688171

2688173

2688174

2688176

2688177

2688179

56618_at

8089438

GE509439

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0043226

GO:0048731

GO:0048856

HMNXSV003042459

Hs.86950.0.A1_3p_at

ILMN_1780790

PH_hs_0016955

TC03001637.hg

Participates

as an input of

DPPA2, DPPA4 and TP53 bind the DUX4 gene cluster (Homo sapiens)

as a component of

DPPA2:DPPA4:p-S15-TP53:DUX4 gene [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENST00000478945, ENSP00000417710

OpenTargets

ENSG00000163530

HPA

ENSG00000163530-DPPA2

PRO

Q7Z7J5

Pharos - Targets

Q7Z7J5

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:Q9Y649 Q9Y649			0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959)	0.556	3
UniProt:Q7KZS0 Q7KZS0			0.556	3
UniProt:P06396 GSN	7	GSN [cytosol] (R-HSA-350275) GSN(28-403) [cytosol] (R-HSA-201618) GSN(404-782) [cytosol] (R-HSA-350272) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3

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