Release of E3 from polyubiquitinated substrate

Stable Identifier
R-HSA-983147
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

K48 polyubiquitinated substrate dissociates from E3 to become a substrate for a multicatalytic complex called the 26S proteasome.

Literature References
PubMed ID Title Journal Year
16954532 A novel family of membrane-bound E3 ubiquitin ligases J Biochem 2006
12646216 U-box proteins as a new family of ubiquitin ligases Biochem Biophys Res Commun 2003
19489725 RING domain E3 ubiquitin ligases Annu Rev Biochem 2009
Participants
Participant Of
Orthologous Events