Release of E3 from polyubiquitinated substrate

Stable Identifier
R-HSA-983147
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

K48 polyubiquitinated substrate dissociates from E3 to become a substrate for a multicatalytic complex called the 26S proteasome.

Literature References
PubMed ID Title Journal Year
16954532 A novel family of membrane-bound E3 ubiquitin ligases

Ohmura-Hoshino, M, Goto, E, Matsuki, Y, Aoki, M, Mito, M, Uematsu, M, Hotta, H, Ishido, S

J Biochem 2006
12646216 U-box proteins as a new family of ubiquitin ligases

Hatakeyama, S, Nakayama, KI

Biochem Biophys Res Commun 2003
19489725 RING domain E3 ubiquitin ligases

Deshaies, RJ, Joazeiro, CA

Annu Rev Biochem 2009
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