Reactome | Kinesins

Kinesins

Stable Identifier

R-HSA-983189

Type

Pathway

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Kinesins are a superfamily of microtubule-based motor proteins that have diverse functions in transport of vesicles, organelles and chromosomes, and regulate microtubule dynamics. There are 14 families of kinesins, all reprsented in humans. A standardized nomenclature was published in 2004 (Lawrence et al.).

Literature References

PubMed ID	Title	Journal	Year
18626067	Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics Hirokawa, N, Noda, Y	Physiol Rev	2008
15479732	A standardized kinesin nomenclature Lawrence, CJ, Dawe, RK, Christie, KR, Cleveland, DW, Dawson, SC, Endow, SA, Goldstein, LS, Goodson, HV, Hirokawa, N, Howard, J, Malmberg, RL, McIntosh, JR, Miki, H, Mitchison, TJ, Okada, Y, Reddy, AS, Saxton, WM, Schliwa, M, Scholey, JM, Vale, RD, Walczak, CE, Wordeman, L	J Cell Biol	2004
	Kinesin home page Greene, E, Henikoff, S
19851335	Traffic control: regulation of kinesin motors Verhey, KJ, Hammond, JW	Nat Rev Mol Cell Biol	2009
20930137	Kinesins at a glance Endow, SA, Kull, FJ, Liu, H	J Cell Sci	2010