Reactome | Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

Stable Identifier

R-HSA-983425

Type

Reaction [binding]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, cytosol, endoplasmic reticulum lumen

ReviewStatus

5/5

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Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

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Sec13-Sec31 binds the prebudding complex and this Sec13-Sec31 heterotetramer forms the outer structural scaffold of the coat. Sec13-Sec31 is likely to crosslink the prebudding complexes generating COPII-coated vesicles.

Literature References

PubMed ID	Title	Journal	Year
10825291	COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites Paccaud, JP, Lin-Marq, N, Stephens, DJ, Pagano, A, Pepperkok, R	J Cell Sci	2000
10982397	Dynamics of transitional endoplasmic reticulum sites in vertebrate cells Glick, BS, Hammond, AT	Mol Biol Cell	2000