Reactome | FAAP20 [cytosol]

FAAP20 [cytosol]

Stable Identifier

R-HSA-9835400

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Fanconi anemia-associated protein of 20 kDa, C1orf86, FP7162

Locations in the PathwayBrowser

Expand all

Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Interferon Signaling (Homo sapiens)
    - Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
      - PKR-mediated signaling (Homo sapiens)
        
        FA core complex:HSP70s binds PKR (Homo sapiens)
        
        FA Core Complex:HSP70s [cytosol] (Homo sapiens)
        
        FA Core Complex [cytosol] (Homo sapiens)
        
        FAAP20 [cytosol] (Homo sapiens)
        
        FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Homo sapiens)
        
        FA Core Complex:HSP70s [cytosol] (Homo sapiens)
        
        FA Core Complex [cytosol] (Homo sapiens)
        
        FAAP20 [cytosol] (Homo sapiens)
        
        PKR forms a dimer (Homo sapiens)
        
        FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Homo sapiens)
        
        FA Core Complex:HSP70s [cytosol] (Homo sapiens)
        
        FA Core Complex [cytosol] (Homo sapiens)
        
        FAAP20 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6NZ36 FAAP20

Gene Names

FAAP20, C1orf86, FP7162

Chain

chain:1-180

Reference Genes

BioGPS Gene:199990 FAAP20

COSMIC (genes):FAAP20 FAAP20

CTD Gene:199990 FAAP20

dbSNP Gene:199990 FAAP20

ENSEMBL:ENSG00000162585 FAAP20

ENSEMBL_homo_sapiens_GENE:ENSG00000162585.17 FAAP20

HGNC:26428 FAAP20

KEGG Gene (Homo sapiens):199990 FAAP20

Monarch:199990 FAAP20

NCBI Gene:199990 FAAP20

OMIM:615183 FAAP20

UCSC:Q6NZ36 FAAP20

Reference Transcript

Other Identifiers

11750777_a_at

11755803_s_at

11757068_s_at

11763700_x_at

1558544_PM_at

1558544_at

16680568

199990

229113_PM_s_at

229113_s_at

236584_PM_at

236584_at

2392090

2392091

2392092

2392093

2392094

2392096

2392097

2392099

2392100

2392102

2392103

2392105

2392106

2392117

2392118

2392119

2392120

2392121

2392122

2392124

2392125

7911683

88849_at

A_24_P49214

A_33_P3254431

A_33_P3359344

A_33_P3359354

GE617702

GO:0000785

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006281

GO:0006974

GO:0016604

GO:0019985

GO:0030054

GO:0031593

GO:0036297

GO:0043130

GO:0043226

GO:0043240

GO:0046872

GO:0070530

GO:0140036

HMNXSV003003249

HMNXSV003004802

HMNXSV003014879

Hs.201396.0.A1_3p_at

Hs.78793.2.S1_3p_s_at

Hs2.432368.1.S1_3p_at

ILMN_2097790

PH_hs_0034549

PH_hs_0036511

TC01002112.hg

Participates

as a component of

FA Core Complex [cytosol] (Homo sapiens)

Other forms of this molecule

FAAP20 [nucleoplasm]

Inferred To

FAAP20 [cytosol] (Bos taurus)

FAAP20 [cytosol] (Canis familiaris)

FAAP20 [cytosol] (Gallus gallus)

FAAP20 [cytosol] (Mus musculus)

FAAP20 [cytosol] (Rattus norvegicus)

FAAP20 [cytosol] (Sus scrofa)

faap20 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001269599.1, NP_001269602.1, NP_001269601.1, NP_001269600.1, NP_872339.2, NP_001243876.1, NP_001243874.1, NP_001243875.1

OpenTargets

ENSG00000162585

GeneCards

Q6NZ36

HPA

ENSG00000162585-FAAP20

Ensembl

ENSP00000383709, ENSP00000410450, ENSP00000367804, ENST00000378546, ENSG00000162585, ENST00000400918, ENSP00000367808, ENST00000378543, ENST00000414253

PRO

Q6NZ36

Pharos - Targets

Q6NZ36

PDB

3WWQ, 2MUR, 2MUQ

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBZ9 REV1	1	REV1 [nucleoplasm] (R-HSA-3006726)	0.544	2