Reactome: A Curated Pathway Database

Ion channel transport

Stable Identifier
R-HSA-983712
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Ion channels mediate the flow of ions across the plasma membrane of cells. They are integral membrane proteins, typically a multimer of proteins, which, when arranged in the membrane, create a pore for the flow of ions. There are different types of ion channels. P-type ATPases undergo conformational changes to translocate ions. Ligand-gated ion channels operate like a gate, opened or closed by a chemical signal. Voltage-gated ion channels are activated by changes in electrical potential difference at the membrane (Purves, 2001; Kuhlbrandt, 2004).

Literature References
PubMed ID Title Journal Year
15071553 Biology, structure and mechanism of P-type ATPases Nat Rev Mol Cell Biol 2004
  Neuroscience (2nd ed.)   2001
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