Ion channel transport

Stable Identifier
R-HSA-983712
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
Summation

Ion channels mediate the flow of ions across the plasma membrane of cells. They are integral membrane proteins, typically a multimer of proteins, which, when arranged in the membrane, create a pore for the flow of ions. There are different types of ion channels. P-type ATPases undergo conformational changes to translocate ions. Ligand-gated ion channels operate like a gate, opened or closed by a chemical signal. Voltage-gated ion channels are activated by changes in electrical potential difference at the membrane (Purves, 2001; Kuhlbrandt, 2004).

Literature References
PubMed ID Title Journal Year
15071553 Biology, structure and mechanism of P-type ATPases

Kühlbrandt, W

Nat Rev Mol Cell Biol 2004
  Neuroscience (2nd ed.)

Purves, D

  2001
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
ion transmembrane transport (0034220)
Orthologous Events
Ion channel transport (Arabidopsis thaliana)
Ion channel transport (Bos taurus)
Ion channel transport (Caenorhabditis elegans)
Ion channel transport (Canis familiaris)
Ion channel transport (Danio rerio)
Ion channel transport (Dictyostelium discoideum)
Ion channel transport (Drosophila melanogaster)
Ion channel transport (Gallus gallus)
Ion channel transport (Mus musculus)
Ion channel transport (Oryza sativa)
Ion channel transport (Plasmodium falciparum)
Ion channel transport (Rattus norvegicus)
Ion channel transport (Saccharomyces cerevisiae)
Ion channel transport (Schizosaccharomyces pombe)
Ion channel transport (Sus scrofa)
Ion channel transport (Taeniopygia guttata)
Ion channel transport (Xenopus tropicalis)
Authored
Jassal, B  (2010-11-02)
Reviewed
He, L  (2010-11-15)