Reactome | APP [mitochondrial inner membrane]

APP [mitochondrial inner membrane]

Stable Identifier

R-HSA-9839060

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

fullName evidence="150"Amyloid-beta precursor protein, A4_HUMAN, APP695

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Locations in the PathwayBrowser for interactor UniProt:Q06481 APLP2

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Literature References

PubMed ID	Title	Journal	Year
12695498	Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells Anandatheerthavarada, HK, Avadhani, NG, Robin, MA, Biswas, G	J Cell Biol	2003
16943564	Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction Anandatheerthavarada, HK, Avadhani, NG, Galati, DF, Prabhu, BM, Devi, L	J Neurosci	2006

External Reference Information

External Reference

UniProt:P05067-4 APP

Gene Names

APP, A4, AD1

Participates

as an input of

HTRA2 degrades APP (Amyloid-beta precursor protein) (Homo sapiens)

Other forms of this molecule

APP (535-695) [cytosol]

Inferred To

Appl [mitochondrial inner membrane] (Drosophila melanogaster)

Homologues of APP [mitochondrial inner membrane] (Sus scrofa)

APP [mitochondrial inner membrane] (Bos taurus)

APP [mitochondrial inner membrane] (Caenorhabditis elegans)

APP [mitochondrial inner membrane] (Canis familiaris)

APP [mitochondrial inner membrane] (Gallus gallus)

APP [mitochondrial inner membrane] (Mus musculus)

APP [mitochondrial inner membrane] (Rattus norvegicus)

APP [mitochondrial inner membrane] (Sus scrofa)

app [mitochondrial inner membrane] (Xenopus tropicalis)

appa [mitochondrial inner membrane] (Danio rerio)

Cross References

RefSeq

NP_000475.1, NP_001191232.1, NP_001129601.1, NP_958816.1, NP_958817.1, NP_001129602.1, NP_001191230.1, NP_001129488.1, NP_001191231.1, NP_001129603.1

OpenTargets

ENSG00000142192

ENSEMBL

ENSG00000142192, ENSP00000387483, ENST00000354192, ENSP00000350578, ENST00000346798, ENST00000357903, ENSP00000351796, ENSP00000345463, ENST00000348990, ENST00000358918, ENSP00000284981, ENST00000440126, ENSP00000346129

ZINC - Substances

A4_HUMAN

ZINC - Biogenic

A4_HUMAN

ZINC target

P05067

PRO

P05067

GlyGen

P05067

PDB

8SEL, 4ONG, 5AEF, 1BJC, 3Q2X, 8QN7, 7Y8Q, 1QWP, 4XXD, 2FK3, 8H8Q, 5C67, 8OL7, 2Y29, 8FF3, 2LZ3, 2IPU, 3UMK, 3BAE, 3DXD, 5MY4, 8BFB, 8OLN, 9CZP, 1MWP, 1ZJD, 7WFY, 6GFI, 6SHS, 6YHP, 3PZZ, 7OXN, 1QXC, 7E6P, 1OWT, 8KF5, 2R0W, 5MYO, 8T82, 8I4O, 1ZE9, 8OWK, 1TKN, 7Y3J, 7OW1, 6RHY, 8FF2, 5MYX, 1AML, 5BUO, 2M9R, 4PQD, 3NYL, 7U4P, 1X11, 7JXO, 2LLM, 1BRC, 4ONF, 6YHX, 7Q4M, 8OL2, 5TXD, 2MVX, 7F29, 4MVL, 1CA0, 8KEW, 8OWJ, 2WK3, 4JFN, 2MJ1, 5VOS, 2MPZ, 2LZ4, 8AZT, 3IFO, 6YHF, 2M9S, 1QYT, 5AM8, 3MXC, 8SEK, 1QCM, 7WVY, 2LNQ, 8T89, 8OTF, 6NB9, 1AAP, 5W3P, 3BKJ, 6ITU, 3OVJ, 5ONP, 8X53, 5HOX, 8EZE, 2MXU, 5LV0, 6TI7, 3NYJ, 8OL6, 2Y2A, 3DXE, 3SV1, 8AZS, 2Y3L, 3IFN, 8OLO, 6XOV, 8BG0, 8OT1, 8KF4, 6O4J, 8OL3, 8B9R, 6OIZ, 5OQV, 3MXY, 4MVK, 4M1C, 8X52, 5ONQ, 2Y3K, 8OWE, 3L81, 2LMN, 7O1Q, 6CO3, 5AMB, 9CZN, 6SZF, 7RTZ, 8EZD, 6TI5, 1TAW, 3IFL, 8OVK, 1HZ3, 7B3J, 8SEJ, 4MVI, 3UMI, 3JQ5, 5LFY, 2Y3J, 2M4J, 8X54, 5VZY, 2G47, 8OWD, 5HOY, 2FK1, 2LMO, 3KTM, 2LOH, 8OL5, 6TI6, 3OW9, 8BFZ, 8OVM, 3JQL, 3JTI, 2NAO, 8OT4, 7B3K, 8KF3, 6WXM, 1BJB, 2FKL, 3UMH, 7Q4B, 2MGT, 1AMB, 5HOW, 2BP4, 3U0T, 8B9Q, 8C3H, 1BA4, 2FMA, 2FK2, 2LMP, 3MOQ, 2BEG, 4MDR, 1IYT, 3DXC, 2LFM, 8OLG, 4PWQ, 8OT3, 7JXN, 5CSZ, 8KF6, 8QN6, 4NGE, 4OJF, 1AMC, 3IFP, 4HIX, 1Z0Q, 3GCI, 3AYU, 6OC9, 6W0O, 1ZE7, 2LMQ, 8KF1, 1BA6, 8BFA, 6IYC, 2LP1, 2OTK, 6YHI, 6YHO, 8OLQ, 2FJZ, 5KK3, 3L33

HPA

ENSG00000142192-APP

GeneCards

APP

Pharos - Targets

P05067

Orphanet

APP

ZINC - Predictions - Purchasable

A4_HUMAN

HMDB Protein

HMDBP01991

Interactors (431)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.993	107
UniProt:O00213 APBB1	1	APBB1 [nucleoplasm] (R-HSA-5683987)	0.912	10
UniProt:P56817 BACE1	8	BACE1 [endosome membrane] (R-HSA-5692942) BACE1(46-501) [plasma membrane] (R-HSA-5692933) BACE1(46-501) [Golgi-associated vesicle lumen] (R-HSA-5693105) 7K-BACE1(46-501) [Golgi-associated vesicle lumen] (R-HSA-5693106) 7K-BACE1 [Golgi-associated vesicle lumen] (R-HSA-5693095) BACE1(22-45) [Golgi-associated vesicle lumen] (R-HSA-5693069) 7K-BACE1 [endoplasmic reticulum lumen] (R-HSA-5693006) BACE1 [endoplasmic reticulum lumen] (R-HSA-6783326)	0.865	11
UniProt:O95704 APBB3			0.847	8
UniProt:Q92870 APBB2			0.785	6
UniProt:Q9UQF2 JIP1			0.783	6
UniProt:Q9Y287 ITM2B	1	ITM2B(244-266) [extracellular region] (R-HSA-976878)	0.775	6
UniProt:P04156 PRNP	2	PRNP [plasma membrane] (R-HSA-375060) PRNP [cytosol] (R-HSA-9617597)	0.775	6
UniProt:P10636 MAPT	3	MAPT [cytosol] (R-HSA-201574) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT(422-758) [cytosol] (R-HSA-350642)	0.749	8
UniProt:Q99714 HSD17B10	1	HSD17B10 [mitochondrial matrix] (R-HSA-70831)	0.747	7
UniProt:P02647 APOA1	11	APOA1(25-266) [extracellular region] (R-HSA-174720) APOA1 [endoplasmic reticulum lumen] (R-HSA-8956724) p-APOA1 [endoplasmic reticulum lumen] (R-HSA-8957081) APOA1(25-266) [endocytic vesicle lumen] (R-HSA-2239460) Variant apolipoprotein AI [extracellular region] (R-HSA-976865) APOA1(25-266) [plasma membrane] (R-HSA-216742) APOA1(19-266) [extracellular region] (R-HSA-264771) APOA1(25-267) [endoplasmic reticulum lumen] (R-HSA-174640) APOA1(25-267) [early endosome] (R-HSA-2429641) APOA1(25-267) [cytosol] (R-HSA-2395781) APOA1(25-266) [secretory granule lumen] (R-HSA-350761)	0.747	8
UniProt:P27797 CALR	6	CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448)	0.737	5
UniProt:Q02410 APBA1	1	APBA1 [cytosol] (R-HSA-5336459)	0.729	5
UniProt:P61812 TGFB2	3	TGFB2 [platelet alpha granule lumen] (R-HSA-65938) TGFB2(20-302) [extracellular region] (R-HSA-2395269) TGFB2 [extracellular region] (R-HSA-114706)	0.705	7
UniProt:P09936 UCHL1	1	UCHL1 [cytosol] (R-HSA-5660679)	0.703	5
UniProt:P30101 PDIA3	3	PDIA3 [recycling endosome membrane] (R-HSA-8863849) PDIA3 [phagocytic vesicle] (R-HSA-1236870) PDIA3 [endoplasmic reticulum lumen] (R-HSA-901028)	0.703	6
UniProt:Q92673 SORL1	2	SORL1 [endosome membrane] (R-HSA-8871475) SORL1 [Golgi membrane] (R-HSA-8871510)	0.69	5
UniProt:Q92876 KLK6			0.683	4
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.675	5
UniProt:Q92529 SHC3	2	SHC3 [cytosol] (R-HSA-3006448) p-Y-SHC3 [cytosol] (R-HSA-3009043)	0.675	5
UniProt:P49810 PSEN2	2	PSEN2(298-448) [plasma membrane] (R-HSA-9013329) PSEN2(1-297) [plasma membrane] (R-HSA-201599)	0.675	4
UniProt:Q03936 ZNF92	1	ZNF92 [nucleoplasm] (R-HSA-975007)	0.667	4
UniProt:O60293 ZFC3H1	1	ZFC3H1 [nucleoplasm] (R-HSA-9930046)	0.667	3
UniProt:P02511 CRYAB	1	CRYAB [nucleoplasm] (R-HSA-6806336)	0.666	7
UniProt:P62937 PPIA	5	PPIA [cytosol] (R-HSA-173123) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [extracellular region] (R-HSA-173646) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [extracellular exosome] (R-HSA-6801538)	0.666	4
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.666	8
UniProt:P11021 HSPA5	6	HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [extracellular region] (R-HSA-351322)	0.666	6
UniProt:P18669 PGAM1	4	PGAM1 [cytosol] (R-HSA-71442) PGAM1 [ficolin-1-rich granule lumen] (R-HSA-6803309) PGAM1 [extracellular region] (R-HSA-6806482) PGAM1 [secretory granule lumen] (R-HSA-6803293)	0.666	4
UniProt:P07437 TUBB	3	TUBB [extracellular region] (R-HSA-380317) TUBB [azurophil granule lumen] (R-HSA-6799370) TUBB [cytosol] (R-HSA-9020816)	0.666	5
UniProt:O96018 APBA3	1	APBA3 [cytosol] (R-HSA-6794262)	0.666	6
UniProt:P60709 ACTB	5	ACTB [plasma membrane] (R-HSA-196016) ACTB [lysosomal membrane] (R-HSA-196160) ACTB [cytosol] (R-HSA-201861) ACTB [nucleoplasm] (R-HSA-3321990) Unfolded ACTB [cytosol] (R-HSA-390462)	0.666	8
UniProt:P07900 HSP90AA1	8	HSP90AA1 [lysosomal lumen] (R-HSA-9622850) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912)	0.666	5
UniProt:P61764 STXBP1	2	STXBP1 [cytosol] (R-HSA-6794256) STXBP1 [plasma membrane] (R-HSA-2980862)	0.666	7
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.659	6
UniProt:O14672 ADAM10	6	ADAM10(215-824) [plasma membrane] (R-HSA-179885) ADAM10 [plasma membrane] (R-HSA-157237) ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956768) p-ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956999) ADAM10 [tertiary granule membrane] (R-HSA-6800992) ADAM10 [specific granule membrane] (R-HSA-6799566)	0.659	7
UniProt:P42574 CASP3	5	CASP3(176-277) [cytosol] (R-HSA-141646) CASP3(29-175) [cytosol] (R-HSA-141644) CASP3(176-277) [nucleoplasm] (R-HSA-211203) CASP3(29-175) [nucleoplasm] (R-HSA-211194) CASP3(1-277) [cytosol] (R-HSA-57021)	0.659	4
UniProt:P36544 CHRNA7	1	CHRNA7 [plasma membrane] (R-HSA-507830)	0.646	4
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.646	4
UniProt:P49768 PSEN1	6	PSEN1(299-467) [plasma membrane] (R-HSA-2534245) PSEN1(1-298) [plasma membrane] (R-HSA-2534298) PSEN1(1-298) [azurophil granule membrane] (R-HSA-6799209) PSEN1(1-467) [azurophil granule membrane] (R-HSA-6799235) PSEN1(299-467) [azurophil granule membrane] (R-HSA-6799234) PSEN1(1-467) [plasma membrane] (R-HSA-201606)	0.632	6
UniProt:O35431 Apba2	1	Apba2 [cytosol] (R-RNO-6794273)	0.618	5
UniProt:P01137 TGFB1	7	TGFB1 [extracellular region] (R-HSA-170838) TGFB1(30-278) [extracellular region] (R-HSA-2395367) TGFB1(30-278) [Golgi lumen] (R-HSA-9736812) TGFB1 [Golgi lumen] (R-HSA-177108) TGFB1(30-390) [Golgi lumen] (R-HSA-114705) TGFB1(30-278) [platelet alpha granule lumen] (R-HSA-65936) TGFB1 [plasma membrane] (R-HSA-5146781)	0.604	3
UniProt:Q99767 APBA2	1	APBA2 [cytosol] (R-HSA-6794245)	0.592	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.59	4
UniProt:Q9NP59 SLC40A1	7	SLC40A1 [plasma membrane] (R-HSA-442390) SLC40A1 A77D [plasma membrane] (R-HSA-5655698) SLC40A1 D157G [plasma membrane] (R-HSA-5655794) SLC40A1 G80V [plasma membrane] (R-HSA-5655697) SLC40A1 D181V [plasma membrane] (R-HSA-5655786) SLC40A1 N144H [plasma membrane] (R-HSA-5655754) SLC40A1 V162del [plasma membrane] (R-HSA-5655818)	0.589	5
UniProt:P29353 SHC1	5	p-Y-SHC1 [cytosol] (R-HSA-162568) SHC1 [cytosol] (R-HSA-74680) p-Y349,Y350,Y427-SHC1 [cytosol] (R-HSA-912321) p-Y349,Y350-SHC1 [cytosol] (R-HSA-180276) p-Y427-SHC1 [cytosol] (R-HSA-74684)	0.589	6
UniProt:P42704 LRPPRC	1	LRPPRC [mitochondrial matrix] (R-HSA-5336174)	0.584	8
UniProt:Q13625 TP53BP2	1	TP53BP2 [nucleoplasm] (R-HSA-6799780)	0.581	3
UniProt:O75955 FLOT1	1	FLOT1 [plasma membrane] (R-HSA-112174)	0.581	5
UniProt:Q9NV96 TMEM30A	3	TMEM30A [specific granule membrane] (R-HSA-6799526) TMEM30A [plasma membrane] (R-HSA-6806278) TMEM30A [azurophil granule membrane] (R-HSA-6799504)	0.564	3
UniProt:P08138 NGFR	7	NGFR [plasma membrane] (R-HSA-193664) NGFR(251-427) [plasma membrane] (R-HSA-194476) NGFR(273-427) [cytosol] (R-HSA-194458) NGFR(251-272) [plasma membrane] (R-HSA-194509) NGFR(251-427) [endosome] (R-HSA-209541) NGFR(29-250) [extracellular region] (R-HSA-194470) NGFR(273-427) [nucleoplasm] (R-HSA-197473)	0.558	2
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q16650 TBR1			0.556	3
UniProt:P62942 FKBP1A	1	FKBP1A [cytosol] (R-HSA-2026007)	0.556	3
UniProt:Q02246 CNTN2	1	CNTN2 [plasma membrane] (R-HSA-373618)	0.556	3
UniProt:Q9NY61 AATF	1	AATF [cytosol] (R-HSA-205071)	0.556	3
UniProt:P68366 TUBA4A	9	TUBA4A [cytosol] (R-HSA-191694) TUBA4A [axonemal microtubule] (R-HSA-5610443) TUBA4A [extracellular region] (R-HSA-350734) Polyglutamyl-TUBA4A [cytosol] (R-HSA-8867386) L-isoglutamyl polyglycyl-TUBA4A [cytosol] (R-HSA-8867378) TUBA4A unfolded [cytosol] (R-HSA-392771) TUBA4A folding intermediate [cytosol] (R-HSA-392800) Ac K40 TUBA4A [axonemal microtubule] (R-HSA-5624859) AcK-TUBA4A [cytosol] (R-HSA-5618318)	0.556	3
UniProt:P14625 HSP90B1	4	HSP90B1 [endocytic vesicle lumen] (R-HSA-3221623) HSP90B1 [extracellular region] (R-HSA-3221653) p-HSP90B1 [endoplasmic reticulum lumen] (R-HSA-8957016) HSP90B1 [endoplasmic reticulum lumen] (R-HSA-981545)	0.556	3
UniProt:P68363 TUBA1B	9	TUBA1B [cytosol] (R-HSA-191691) TUBA1B [axonemal microtubule] (R-HSA-5610434) TUBA1B(1-450) [cytosol] (R-HSA-8955581) Polyglutamyl-TUBA1B [cytosol] (R-HSA-8867435) L-isoglutamyl polyglycyl-TUBA1B [cytosol] (R-HSA-8867436) TUBA1B unfolded [cytosol] (R-HSA-392781) TUBA1B folding intermediate [cytosol] (R-HSA-392797) Ac K40 TUBA1B [axonemal microtubule] (R-HSA-5624854) AcK-TUBA1B [cytosol] (R-HSA-5618285)	0.556	3
UniProt:Q8IU99 CALHM1	1	CALHM1 [plasma membrane] (R-HSA-2889051)	0.556	3
UniProt:O75888-3 TNFSF13			0.556	3
UniProt:Q05BL1 Q05BL1			0.556	3
UniProt:Q99719 SEPT5			0.556	3
UniProt:Q13393 PLD1	4	PLD1 [specific granule membrane] (R-HSA-6799531) PLD1 [tertiary granule membrane] (R-HSA-6800955) PLD1 [plasma membrane] (R-HSA-2028998) PLD1 [endoplasmic reticulum membrane] (R-HSA-1498795)	0.556	3
UniProt:Q8WW43 APH1B	2	APH1B [endosome membrane] (R-HSA-9010060) APH1B [plasma membrane] (R-HSA-157340)	0.556	3
IntAct:EBI-25936029 EBI11820565			0.556	3
UniProt:Q6IPE9 Q6IPE9			0.556	3
UniProt:P14735 IDE	5	IDE [endosome lumen] (R-HSA-9794504) IDE [cytosol] (R-HSA-9033133) IDE [peroxisomal matrix] (R-HSA-9033157) PolyUb-IDE [mitochondrial outer membrane] (R-HSA-6783095) IDE [mitochondrial outer membrane] (R-HSA-5696861)	0.556	3
UniProt:P43405-2 P434052			0.556	3
UniProt:Q13148 TADBP			0.556	6
UniProt:P02766 TTR	2	TTR [azurophil granule lumen] (R-HSA-6799366) TTR [extracellular region] (R-HSA-976883)	0.556	3
IntAct:EBI-25936019 CCSB			0.556	3
UniProt:P19544-6 WT1			0.556	3
UniProt:Q6ZNA4-2 Q6ZNA42			0.556	3
UniProt:P48730 CSNK1D	3	CSNK1D [cytosol] (R-HSA-380315) CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5685717) CSNK1D [nucleoplasm] (R-HSA-421305)	0.556	3
UniProt:O43236 SEPT4			0.556	3
UniProt:O60260-5 PRKN			0.556	5
UniProt:Q96FW1 OTUB1	2	OTUB1 [cytosol] (R-HSA-933411) OTUB1 [nucleoplasm] (R-HSA-6783242)	0.556	3
UniProt:Q13113 PDZ1I			0.556	3
IntAct:EBI-25880053 IOH23180			0.556	3
UniProt:P48736 PIK3CG	1	PIK3CG [cytosol] (R-HSA-392286)	0.556	3
UniProt:Q16740 CLPP	1	CLPP [mitochondrial matrix] (R-HSA-9838002)	0.556	3
UniProt:Q6AZY7-2 Q6AZY72			0.556	3
IntAct:EBI-25936001 CCSB			0.556	3
UniProt:Q9BYZ2 LDHAL6B	1	LDHAL6B [mitochondrial matrix] (R-HSA-6807613)	0.556	3
UniProt:P00491 PNP	7	PNP [ficolin-1-rich granule lumen] (R-HSA-6803278) PNP [extracellular region] (R-HSA-6806505) PNP [secretory granule lumen] (R-HSA-6803318) PNP [cytosol] (R-HSA-61933) PNP D128G [cytosol] (R-HSA-9735785) PNP E89K [cytosol] (R-HSA-9735781) PNP R234P [cytosol] (R-HSA-9735772)	0.556	9
UniProt:Q9UJC3 HOOK1			0.556	3
UniProt:Q9BX74 TM2D1			0.556	3
UniProt:P49711 CTCF	1	CTCF [nucleoplasm] (R-HSA-3782562)	0.556	3
UniProt:Q13485 SMAD4	20	SMAD4 P356R [cytosol] (R-HSA-3310988) SMAD4 K428T [cytosol] (R-HSA-3311004) SMAD4 D351del [cytosol] (R-HSA-3310974) SMAD4 R361H [cytosol] (R-HSA-3310984) SMAD4 P356L [cytosol] (R-HSA-3310987) SMAD4 A406T [cytosol] (R-HSA-3311003) SMAD4 D351Y [cytosol] (R-HSA-3310970) SMAD4 D351H [cytosol] (R-HSA-3310965) SMAD4 R361C [cytosol] (R-HSA-3310983) SMAD4 D351G [cytosol] (R-HSA-3310967) SMAD4 R515T [cytosol] (R-HSA-3311008) SMAD4 G352* [cytosol] (R-HSA-9678445) SMAD4 S178* [cytosol] (R-HSA-9675630) SMAD4 G477* [cytosol] (R-HSA-9678447) SMAD4 G473* [cytosol] (R-HSA-9678440) SMAD4 S144* [cytosol] (R-HSA-9675625) SMAD4 E538* [cytosol] (R-HSA-9675626) SMAD4 E390* [cytosol] (R-HSA-9675620) SMAD4 S154* [cytosol] (R-HSA-9675621) SMAD4 E330* [cytosol] (R-HSA-9675622)	0.556	3
UniProt:P16234-2 PDGFRA			0.556	3
UniProt:Q16512 PKN1	3	p-T774-PKN1 [cytosol] (R-HSA-5623651) PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:P11277 SPTB	1	SPTB [cytosol] (R-HSA-391565)	0.556	6
UniProt:Q96S59 RANBP9	1	RANBP9 [cytosol] (R-HSA-374586)	0.556	3
UniProt:O14939 PLD2	2	PLD2 [plasma membrane] (R-HSA-2029075) PLD2 [endoplasmic reticulum membrane] (R-HSA-1498791)	0.556	3
UniProt:Q14790 CASP8	8	CASP8(1-479) [cytosol] (R-HSA-57031) CASP8(1-216) [cytosol] (R-HSA-933456) CASP8(217-374) [cytosol] (R-HSA-75975) CASP8(375-384) [cytosol] (R-HSA-933460) CASP8(385-479) [cytosol] (R-HSA-76158) CASP8(385-479) [mitochondrial outer membrane] (R-HSA-351828) CASP8(217-374) [mitochondrial outer membrane] (R-HSA-351869) CASP8(1-374) [cytosol] (R-HSA-3465404)	0.556	3
UniProt:Q00266 MAT1A	4	MAT1A H277Afs75 [cytosol] (R-HSA-5603099) MAT1A V348Gfs3 [cytosol] (R-HSA-5603112) MAT1A K181Vfs*5 [cytosol] (R-HSA-5603077) MAT1A [cytosol] (R-HSA-174379)	0.556	3
UniProt:Q9GZQ8 MAP1LC3B	3	MAP1LC3B [cytosol] (R-HSA-5205651) MAP1LC3B(2-121) [cytosol] (R-HSA-5682674) MAP1LC3B [autophagosome membrane] (R-HSA-5683641)	0.556	3
UniProt:Q06481-5 APLP2			0.556	3
UniProt:P41586-2 ADCYAP1R1			0.556	3
UniProt:Q9GZS3 SKIC8	2	WDR61 [cytosol] (R-HSA-8931534) WDR61 [nucleoplasm] (R-HSA-8866696)	0.556	3
UniProt:Q9BS26 ERP44	2	ERP44 [extracellular region] (R-HSA-6806302) ERP44 [specific granule lumen] (R-HSA-6799567)	0.556	3
IntAct:EBI-25934154 EBI16882364			0.556	3
UniProt:O75116 ROCK2	2	ROCK2 [cytosol] (R-HSA-419058) Activated ROCK2 [cytosol] (R-HSA-4687775)	0.556	6
UniProt:P21333-2 FLNA			0.556	3
UniProt:Q00005 2ABB			0.556	3
UniProt:Q92599-3 SEPTIN8			0.556	3
UniProt:Q9Y5Q9 GTF3C3	1	GTF3C3 [nucleoplasm] (R-HSA-83691)	0.556	3
IntAct:EBI-25857140 ORF			0.556	3
UniProt:Q16828 DUSP6	2	DUSP6 [cytosol] (R-HSA-5675343) DUSP6 [nucleoplasm] (R-HSA-2871619)	0.556	3
UniProt:O14662-5 STX16			0.556	3
UniProt:P60891 PRPS1	1	PRPS1 [cytosol] (R-HSA-73483)	0.556	3
UniProt:Q8WV41 SNX33			0.556	3
UniProt:O00744 WNT10B	9	WNT10B [extracellular region] (R-HSA-517471) N4GlycoAsn-PalmS WNT10B [extracellular exosome] (R-HSA-3781957) N4GlycoAsn-PalmS WNT10B [endocytic vesicle membrane] (R-HSA-3781985) WNT10B [endoplasmic reticulum lumen] (R-HSA-3238279) N4GlycoAsn-WNT10B [endoplasmic reticulum lumen] (R-HSA-3238220) N4GlycoAsn-PalmS WNT10B [endoplasmic reticulum lumen] (R-HSA-3238333) N4GlycoAsn-PalmS WNT10B [Golgi lumen] (R-HSA-3247821) N4GlycoAsn-PalmS WNT10B [extracellular region] (R-HSA-3247775) N4GlycoAsn-PalmS WNT10B [plasma membrane] (R-HSA-3247791)	0.556	3
UniProt:Q8NHT4 Q8NHT4			0.556	3
UniProt:Q9UGJ0-3 Q9UGJ03			0.556	3
UniProt:P04406 GAPDH	1	GAPDH [cytosol] (R-HSA-70428)	0.556	3
UniProt:P01011 SERPINA3	4	SERPINA3 [azurophil granule lumen] (R-HSA-6798754) SERPINA3 [secretory granule lumen] (R-HSA-6801018) SERPINA3 [extracellular region] (R-HSA-6806173) SERPINA3 [platelet alpha granule lumen] (R-HSA-8848913)	0.556	3
UniProt:P01375 TNF	5	TNF(1-233) [plasma membrane] (R-HSA-66220) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375)	0.556	3
UniProt:P49755 TMED10	5	TMED10 [Golgi membrane] (R-HSA-6808801) TMED10 [transport vesicle] (R-HSA-6808802) TMED10 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689845) TMED10 [ER to Golgi transport vesicle membrane] (R-HSA-5689843) TMED10 [endoplasmic reticulum membrane] (R-HSA-5689479)	0.556	3
IntAct:EBI-25834291 CCSB			0.556	3
UniProt:P62837 UBE2D2	4	Ub-C85-UBE2D2 [cytosol] (R-HSA-8864214) UBE2D2 [cytosol] (R-HSA-934628) UBE2D2 [nucleoplasm] (R-HSA-8852067) Ub-C85-UBE2D2 [nucleoplasm] (R-HSA-8864153)	0.556	3
UniProt:O43680 TCF21			0.556	3
UniProt:Q13564 NAE1	1	NAE1 [cytosol] (R-HSA-8951449)	0.556	3
UniProt:Q13561 DCTN2	1	DCTN2 [cytosol] (R-HSA-380302)	0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P23142-4 FBLN1			0.556	3
UniProt:P01138 NGF	7	NGF [extracellular region] (R-HSA-167034) NGF(19-241) [endoplasmic reticulum lumen] (R-HSA-187047) NGF(19-241) [Golgi lumen] (R-HSA-187036) NGF(1-241) [endoplasmic reticulum lumen] (R-HSA-187026) NGF [cytosol] (R-HSA-190059) NGF [Golgi lumen] (R-HSA-166515) NGF(19-241) [extracellular region] (R-HSA-187033)	0.556	9
UniProt:Q92870-2 Q928702			0.556	3
UniProt:P41271-2 NBL1			0.556	3
UniProt:P18827 SDC1	20	HS(4)-SDC1 [plasma membrane] (R-HSA-2076693) HS(6)-SDC1 [plasma membrane] (R-HSA-2076652) HS(2)-SDC1 [plasma membrane] (R-HSA-2076666) HS(1)-SDC1 [plasma membrane] (R-HSA-2076672) HS(3)-SDC1 [plasma membrane] (R-HSA-2076691) HS(5)-SDC1 [plasma membrane] (R-HSA-2076626) SDC1 [plasma membrane] (R-HSA-174758) SDC1 [Golgi lumen] (R-HSA-2054105) XylS-SDC1 [Golgi lumen] (R-HSA-2064146) Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064148) Gal-Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064247) GlcA-Gal-Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064082) HS(2)-SDC1 [Golgi lumen] (R-HSA-2076309) HS(3)-SDC1 [Golgi lumen] (R-HSA-2076444) HS(1)-SDC1 [Golgi lumen] (R-HSA-2076321) Heparan(4)-SDC1 [Golgi lumen] (R-HSA-2076339) Heparan(3)-SDC1 [Golgi lumen] (R-HSA-2076314) Heparan(2)-SDC1 [Golgi lumen] (R-HSA-2076558) Heparan(1)-SDC1 [Golgi lumen] (R-HSA-2076349) Heparan-SDC1 [Golgi lumen] (R-HSA-2076561)	0.556	3
UniProt:P17612 PRKACA	4	PRKACA [cytosol] (R-HSA-57844) PRKACA [nucleoplasm] (R-HSA-111936) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [mitochondrial matrix] (R-HSA-9838291)	0.556	3
UniProt:P22694-8 PRKACB			0.556	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
UniProt:Q8WTV0 SCARB1			0.556	3
UniProt:Q92993-2 KAT5			0.556	3
UniProt:P26441 CNTF	1	CNTF [extracellular region] (R-HSA-5696441)	0.556	3
UniProt:P17980 PSMC3	5	PSMC3 [cytosol] (R-HSA-68774) PSMC3 [nucleoplasm] (R-HSA-174313) PSMC3 [ficolin-1-rich granule lumen] (R-HSA-6800429) PSMC3 [extracellular region] (R-HSA-6806496) PSMC3 [secretory granule lumen] (R-HSA-6800917)	0.556	6
UniProt:Q8N895 ZN366			0.556	3
UniProt:P29466-3 CASP1			0.556	3
UniProt:P12036 NFH			0.556	3
UniProt:O60749 SNX2	2	SNX2 [Golgi membrane] (R-HSA-434333) SNX2 [cytoplasmic vesicle membrane] (R-HSA-434216)	0.556	3
UniProt:Q96AX1 VPS33A	1	VPS33A [endosome membrane] (R-HSA-2197804)	0.556	3
UniProt:P61204 ARF3	2	ARF3 [cytosol] (R-HSA-6807733) ARF3 [Golgi membrane] (R-HSA-1604608)	0.556	3
UniProt:P04792 HSBP1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:Q3B7T1 EDRF1			0.556	3
UniProt:P28062-2 PSMB8			0.556	3
UniProt:P01034 CST3	6	Variant cystatin-C [extracellular region] (R-HSA-976891) CST3 [tertiary granule lumen] (R-HSA-6801370) CST3 [extracellular region] (R-HSA-6801534) CST3 [ficolin-1-rich granule lumen] (R-HSA-6801383) p-CST3 [endoplasmic reticulum lumen] (R-HSA-8956911) CST3 [endoplasmic reticulum lumen] (R-HSA-8956740)	0.556	3
UniProt:P46379-2 BAG6			0.556	5
UniProt:Q15583-2 TGIF1			0.556	3
UniProt:Q92934 BAD	4	p-S99-BAD [cytosol] (R-HSA-198335) BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297)	0.556	3
UniProt:Q13303 KCNAB2	3	KCNAB2 [tertiary granule membrane] (R-HSA-6800890) KCNAB2 [plasma membrane] (R-HSA-1297366) KCNAB2 [specific granule membrane] (R-HSA-6799627)	0.556	3
UniProt:Q8NE08 Q8NE08			0.556	3
UniProt:Q01658 DR1	1	DR1 [nucleoplasm] (R-HSA-3662280)	0.556	3
IntAct:EBI-25911596 CCSB			0.556	3
IntAct:EBI-25939806 RZPDO834E0519D			0.556	3
UniProt:Q8WUB8-2 PHF10			0.556	3
UniProt:P48454 PPP3CC	1	PPP3CC [cytosol] (R-HSA-61113)	0.556	3
UniProt:P63010-2 AP2B1			0.556	3
UniProt:P16671 CD36	5	4xPalmC-CD36 [plasma membrane] (R-HSA-51645) 4xPalmC-CD36 [specific granule membrane] (R-HSA-6806151) CD36 [phagocytic vesicle] (R-HSA-1236835) 4xPalmC-CD36 [endocytic vesicle membrane] (R-HSA-2239449) CD36 [platelet alpha granule membrane] (R-HSA-114687)	0.556	3
IntAct:EBI-25830852 RZPDO839G03145			0.556	3
UniProt:Q99547 MPHOSPH6	2	MPHOSPH6 [nucleolus] (R-HSA-9935781) MPHOSPH6 [nucleoplasm] (R-HSA-6791553)	0.556	3
UniProt:O75604-3 USP2			0.556	3
UniProt:Q13765 NACA			0.556	3
UniProt:Q92915 FGF14	1	FGF14 [cytosol] (R-HSA-5578837)	0.556	3
UniProt:P21917 DRD4	1	DRD4 [plasma membrane] (R-HSA-390809)	0.556	6
UniProt:P18509 ADCYAP1	4	ADCYAP1(132-158) [extracellular region] (R-HSA-420144) ADCYAP1(82-129) [extracellular region] (R-HSA-420254) ADCYAP1(132-169) [extracellular region] (R-HSA-420282) ADCYAP1(2-742) [Golgi membrane] (R-HSA-187679)	0.556	3
UniProt:P17535 JUND	1	JUND [nucleoplasm] (R-HSA-9009924)	0.556	3
UniProt:P11171-2 EPB41			0.556	3
UniProt:Q9P0L2 MARK1			0.556	3
UniProt:P11171-7 EPB41			0.556	3
UniProt:Q9C026 TRIM9	1	TRIM9 [cytosol] (R-HSA-976054)	0.556	3
UniProt:O94851 MICA2			0.556	3
UniProt:P10909 CLU	4	CLU(23-449) [extracellular region] (R-HSA-349732) CLU(23-449) [platelet alpha granule lumen] (R-HSA-349733) CLU(228-449) [extracellular region] (R-HSA-6810626) CLU(23-227) [extracellular region] (R-HSA-6810660)	0.556	3
UniProt:P30519 HMOX2	3	HMOX2 [endoplasmic reticulum membrane] (R-HSA-189391) HMOX2 [specific granule membrane] (R-HSA-6799628) HMOX2 [plasma membrane] (R-HSA-6799676)	0.556	3
UniProt:A4FUJ8 A4FUJ8			0.556	3
UniProt:O43852-3 CALU			0.556	3
UniProt:P48730-2 CSNK1D			0.556	3
UniProt:O14656 TOR1A	1	TOR1A [cytosol] (R-HSA-8862858)	0.556	3
UniProt:P07602 PSAP	11	PSAP(326-340) [extracellular region] (R-HSA-5336179) PSAP(?-?) [extracellular region] (R-HSA-5336190) PSAP(17-524) [azurophil granule membrane] (R-HSA-6799212) PSAP(17-524) [plasma membrane] (R-HSA-6806262) PSAP [lysosomal lumen] (R-HSA-9840325) PSAP(60-142) [lysosomal lumen] (R-HSA-351333) PSAP(195-273) [lysosomal lumen] (R-HSA-9840336) PSAP(311-391) [lysosomal membrane] (R-HSA-1605602) PSAP(405-486) [lysosomal lumen] (R-HSA-9840328) PSAP(311-391) [lysosomal lumen] (R-HSA-9851355) PSAP(60-142) [extracellular region] (R-HSA-351338)	0.556	3
UniProt:P04216 THY1	2	cleaved GPI-THY1 [extracellular region] (R-HSA-8941025) GPI-THY1 [plasma membrane] (R-HSA-8940792)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:Q96FE5 LINGO1	1	LINGO1 [plasma membrane] (R-HSA-3006563)	0.556	3
UniProt:Q13867 BLMH	1	BLMH [cytosol] (R-HSA-983095)	0.556	3
UniProt:P43250-2 GRK6			0.556	3
UniProt:O14645 IDLC			0.556	3
IntAct:EBI-25891095 CCSB			0.556	3
UniProt:P05556 ITGB1	2	ITGB1 [plasma membrane] (R-HSA-57596) ITGB1 [endosome membrane] (R-HSA-9611157)	0.556	3
UniProt:Q13501 SQSTM1	7	SQSTM1 [cytosol] (R-HSA-193937) SQSTM1 [nucleoplasm] (R-HSA-210961) ub K420 p-S349 SQSTM1 [cytosol] (R-HSA-9766536) p-S349 SQSTM1 [cytosol] (R-HSA-9766524) K7 ub-SQSTM1 [cytosol] (R-HSA-9759088) SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711954) SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711967)	0.556	6
UniProt:Q14203-5 DCTN1			0.556	5
UniProt:Q9Y5Z0 BACE2			0.556	3
UniProt:Q00403 GTF2B	1	GTF2B [nucleoplasm] (R-HSA-65888)	0.556	3
UniProt:O76041 NEBL			0.556	3
UniProt:Q6PK61 Q6PK61			0.556	3
UniProt:P01116-2 KRAS	8	S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9647815) S-Farn-Me KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649690) S-Farn KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649698) S-Farn proKRAS4B [endoplasmic reticulum membrane] (R-HSA-9649693) pro-KRAS4B [cytosol] (R-HSA-9649686) pS181-S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9653482) pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane] (R-HSA-9653578) S-Farn-Me KRAS4B [cytosol] (R-HSA-9654510)	0.556	3
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.556	3
UniProt:Q7Z2H8 SLC36A1	1	SLC36A1 [plasma membrane] (R-HSA-375419)	0.556	3
UniProt:P10809 HSPD1	6	HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.556	6
UniProt:P62328 TMSB4X	2	TMSB4X [extracellular region] (R-HSA-349753) TMSB4X [platelet alpha granule lumen] (R-HSA-349758)	0.556	3
UniProt:P61586 RHOA	6	RHOA [plasma membrane] (R-HSA-194510) RHOA [cell junction] (R-HSA-2134503) RHOA [cytosol] (R-HSA-194866) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971)	0.556	3
UniProt:Q15714-2 TSC22D1			0.556	3
UniProt:Q8TDB4 HUMMR			0.556	3
UniProt:Q00535 CDK5	4	CDK5 [cytosol] (R-HSA-180064) p-Y15-CDK5 [cytosol] (R-HSA-399809) p-Y15,S159-CDK5 [nucleoplasm] (R-HSA-6805249) CDK5 [nucleoplasm] (R-HSA-8863586)	0.556	3
UniProt:P13051-2 UNG			0.556	3
UniProt:P27824-2 P278242			0.556	3
UniProt:Q99466 NOTCH4	20	NOTCH4(1432-1466) [plasma membrane] (R-HSA-157635) NEXT4 [plasma membrane] (R-HSA-157641) p-4S-NICD4 [cytosol] (R-HSA-9604329) NICD4 [cytosol] (R-HSA-157636) p-NICD4 [nucleoplasm] (R-HSA-9604611) PolyUb-p-NICD4 [nucleoplasm] (R-HSA-9604624) NOTCH4(1337-2003) [Golgi membrane] (R-HSA-157073) 12xFucT-8xGlcS-6xFucS-NOTCH4(24-1336) [Golgi membrane] (R-HSA-1983674) 12xFucT-11xGlcS-6xFucS-NOTCH4(24-1336) [extracellular region] (R-HSA-1983677) NOTCH4(1337-2003) [plasma membrane] (R-HSA-157213) 12xFucT-8xGlcS-6xFucS-NOTCH4(24-2003) [Golgi membrane] (R-HSA-1472876) 12xFucT-8xGlcS-6xFucS-NOTCH4(24-2003) [endoplasmic reticulum membrane] (R-HSA-1467405) 12xFucT-6xFucS-NOTCH4(24-2003) [endoplasmic reticulum membrane] (R-HSA-1467340) Pre-NOTCH4 [endoplasmic reticulum membrane] (R-HSA-157121) FRINGE-modified NOTCH4 Extracellular fragment (NECD4) [Golgi membrane] (R-HSA-1911523) FRINGE-modified NOTCH4 Extracellular Fragment (NECD4) [plasma membrane] (R-HSA-1911521) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH4 [Golgi membrane] (R-HSA-1911507) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH4 [Golgi membrane] (R-HSA-1911422) Glc,GlcNAc-Fuc-Pre-NOTCH4 [Golgi membrane] (R-HSA-1911431) NICD4 [nucleoplasm] (R-HSA-157945)	0.556	3
UniProt:A0AVL1 A0AVL1			0.556	3
UniProt:Q8TBC4 UBA3	2	UBA3 [cytosol] (R-HSA-947632) G76-NEDD8-C237-UBA3 [cytosol] (R-HSA-8951640)	0.556	3
UniProt:P42773 CDKN2C	1	CDKN2C [cytosol] (R-HSA-182572)	0.556	3
UniProt:Q96L34 MARK4	1	MARK4 [cytosol] (R-HSA-5626653)	0.556	3
UniProt:O94985-2 CLSTN1			0.556	3
UniProt:P20340-2 RAB6A			0.556	3
UniProt:Q08722-3 CD47			0.556	3
UniProt:Q02818 NUCB1	2	p-NUCB1 [endoplasmic reticulum lumen] (R-HSA-8957027) NUCB1 [endoplasmic reticulum lumen] (R-HSA-8956751)	0.556	3
UniProt:P16112 ACAN	20	N-glycan ACAN [Golgi lumen] (R-HSA-2046164) Gal-glycan ACAN [Golgi lumen] (R-HSA-2046224) Keratan(1)-ACAN [Golgi lumen] (R-HSA-2046214) Keratan(2)-ACAN [Golgi lumen] (R-HSA-2046311) Keratan(3)-ACAN [Golgi lumen] (R-HSA-2046207) Keratan(4)-ACAN [Golgi lumen] (R-HSA-2046174) KS(1)-ACAN [Golgi lumen] (R-HSA-2046278) KS(2)-ACAN [Golgi lumen] (R-HSA-2046200) KS(2)-ACAN [extracellular region] (R-HSA-2046287) KS(2)-ACAN [lysosomal lumen] (R-HSA-2046195) ACAN [lysosomal lumen] (R-HSA-2105015) KS(2),CSE-ACAN [extracellular region] (R-HSA-2318627) KS(2),C4S-ACAN [extracellular region] (R-HSA-2318645) KS(2),C6S-ACAN [extracellular region] (R-HSA-2318671) KS(2),C4S-ACAN(361-2415) [extracellular region] (R-HSA-3814812) KS(2),C6S-ACAN(361-2415) [extracellular region] (R-HSA-3814813) KS(2),CSE-ACAN(361-2415) [extracellular region] (R-HSA-3814817) KS(2),C6S-ACAN(17-360) [extracellular region] (R-HSA-3814811) KS(2),C4S-ACAN(17-360) [extracellular region] (R-HSA-3814825) KS(2),CSE-ACAN(17-360) [extracellular region] (R-HSA-3814818)	0.556	3
IntAct:EBI-25935974 CCSB			0.556	3
UniProt:Q16363-3 Q163633			0.556	3
UniProt:P32745 SSTR3	2	SSTR3 [ciliary membrane] (R-HSA-5624095) SSTR3 [plasma membrane] (R-HSA-374732)	0.556	3
UniProt:Q8N0S8 Q8N0S8			0.556	3
UniProt:Q8N2W9 PIAS4	2	PIAS4 [nucleoplasm] (R-HSA-2993789) monoSUMO1-K35-PIAS4 [nucleoplasm] (R-HSA-3968415)	0.556	3
UniProt:P09958 FURIN	6	FURIN [Golgi membrane] (R-HSA-157049) FURIN [extracellular region] (R-HSA-1181103) FURIN [plasma membrane] (R-HSA-2159856) FURIN [Golgi lumen] (R-HSA-448351) FURIN [trans-Golgi network membrane] (R-HSA-9832627) FURIN [macropinosome membrane] (R-HSA-9837714)	0.556	3
UniProt:Q6P4J0 Q6P4J0			0.556	3
UniProt:P61278 SST	2	SST(103-116) [extracellular region] (R-HSA-374738) SST(89-116) [extracellular region] (R-HSA-374710)	0.556	3
UniProt:Q9Y272 RASD1			0.556	3
UniProt:Q8N594 MPND			0.556	3
IntAct:EBI-25935964 CCSB			0.556	3
UniProt:P61158 ACTR3	1	ACTR3 [cytosol] (R-HSA-200811)	0.556	3
UniProt:Q99497 PARK7	7	PolyUb-Misfolded PARK7 [lysosomal lumen] (R-HSA-9659997) PolyUb-Misfolded PARK7 [cytosol] (R-HSA-9641128) Ub-Misfolded PARK7 [cytosol] (R-HSA-9641123) Misfolded PARK7 [cytosol] (R-HSA-9641100) PolyUb-Misfolded PARK7 [late endosome lumen] (R-HSA-9660005) PARK7 [nucleoplasm] (R-HSA-3900141) monoSUMO1-K130-PARK7 [nucleoplasm] (R-HSA-4085351)	0.556	3
UniProt:P30533 AMRP			0.556	3
UniProt:P19419 ELK1	2	ELK1 [nucleoplasm] (R-HSA-3009346) p-4S,T336-ELK1 [nucleoplasm] (R-HSA-3009350)	0.556	3
UniProt:Q9Y2W7 KCNIP3	2	KCNIP3 [plasma membrane] (R-HSA-5577044) KCNIP3 [nucleoplasm] (R-HSA-9640052)	0.556	3
UniProt:Q92624 APBP2			0.556	3
UniProt:P29400-2 COL4A5			0.556	3
UniProt:P40227 CCT6A	1	CCT6A [cytosol] (R-HSA-390454)	0.556	3
UniProt:Q6DN90-2 Q6DN902			0.556	3
UniProt:P25090 FPR2	4	FPR2 [plasma membrane] (R-HSA-416408) FPR2 [tertiary granule membrane] (R-HSA-6803296) FPR2 [specific granule membrane] (R-HSA-6803319) FPR2 [ficolin-1-rich granule membrane] (R-HSA-6803335)	0.556	3
UniProt:Q8IWL8 STH			0.556	3
UniProt:Q9ULX5 RN112			0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:P23560-2 BDNF			0.556	3
UniProt:P49841-2 GSK3B			0.556	3
IntAct:EBI-25935954 CCSB			0.556	3
UniProt:Q16082 HSPB2			0.556	3
UniProt:P28482 MAPK1	18	p-T185,Y187-MAPK1 [nucleoplasm] (R-HSA-112354) p-T185,Y187-MAPK1 [cytosol] (R-HSA-109853) MAPK1 [cytosol] (R-HSA-59282) MAPK1 [nucleoplasm] (R-HSA-199960) p-T185-MAPK1 [cytosol] (R-HSA-9635773) p-T185,Y187 MAPK1 P58G [cytosol] (R-HSA-9652802) p-T185,Y187 MAPK1 E322A [cytosol] (R-HSA-9652794) p-T185,Y187 MAPK1 D321N [cytosol] (R-HSA-9652785) p-T185,Y187 MAPK1 D321V [cytosol] (R-HSA-9652791) p-T185,Y187 MAPK1 P58L [cytosol] (R-HSA-9652806) p-T185,Y187 MAPK1 S142L [cytosol] (R-HSA-9652808) p-T185,Y187 MAPK1 E81K [cytosol] (R-HSA-9652799) p-T185,Y187 MAPK1 E322K [cytosol] (R-HSA-9652175) p-T185,Y187 MAPK1 E322V [cytosol] (R-HSA-9652797) MAPK1 [ficolin-1-rich granule lumen] (R-HSA-6800964) MAPK1 [extracellular region] (R-HSA-6806250) MAPK1 [azurophil granule lumen] (R-HSA-6799225) MAPK1 [endoplasmic reticulum lumen] (R-HSA-9636293)	0.556	3
UniProt:P09619 PDGFRB	3	p-12Y-PDGFRB [plasma membrane] (R-HSA-186803) PDGFRB [plasma membrane] (R-HSA-186767) p-11Y-PDGFRB [plasma membrane] (R-HSA-8864039)	0.556	3
UniProt:P53778 MAPK12	3	MAPK12 [nucleoplasm] (R-HSA-448833) p-T183,Y185-MAPK12 [cytosol] (R-HSA-171021) MAPK12 [cytosol] (R-HSA-171025)	0.556	3
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.556	3
UniProt:P04049 RAF1	20	p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094)	0.556	3
UniProt:Q99932-2 SPAG8			0.556	3
UniProt:Q15084 PDIA6	3	PDIA6 [endoplasmic reticulum lumen] (R-HSA-3009049) p-PDIA6 [endoplasmic reticulum lumen] (R-HSA-8957031) PDIA6 [endoplasmic reticulum membrane] (R-HSA-535530)	0.556	3
UniProt:P04181 OAT	1	PXLP-OAT(26-439) [mitochondrial matrix] (R-HSA-70638)	0.556	3
UniProt:P42338 PIK3CB	1	PIK3CB [cytosol] (R-HSA-74788)	0.556	3
UniProt:P04183 TK1	1	TK1 [cytosol] (R-HSA-73500)	0.556	3
UniProt:P06241 FYN	6	FYN [cytosol] (R-HSA-200917) MyrG-p-Y420-FYN [plasma membrane] (R-HSA-1810410) p-Y420-FYN [cytosol] (R-HSA-391821) MyrG2-PalmC3,6-FYN [plasma membrane] (R-HSA-9606873) p-Y531-FYN [cytosol] (R-HSA-391819) p-S21,Y420-FYN [cytosol] (R-HSA-5218745)	0.556	3
IntAct:EBI-25935944 CCSB			0.556	3
UniProt:P63151 PPP2R2A	2	PPP2R2A [nucleoplasm] (R-HSA-1564978) PPP2R2A [cytosol] (R-HSA-377253)	0.556	3
UniProt:O14494 PLPP1	1	PLPP1 [plasma membrane] (R-HSA-76106)	0.556	3
UniProt:P23443-4 RPS6KB1			0.556	3
UniProt:Q0P5N6 ARL16			0.556	3
UniProt:P02686-2 MBP			0.556	3
UniProt:P05026 ATP1B1	1	ATP1B1 [plasma membrane] (R-HSA-375071)	0.556	3
UniProt:P15086 CPB1	2	CPB1 [extracellular region] (R-HSA-3229247) pro-CPB1 [zymogen granule] (R-HSA-9922768)	0.556	3
UniProt:Q9BTD3 TM121			0.556	3
IntAct:EBI-25935934 CCSB			0.556	3
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.556	3
UniProt:Q9BXM7 PINK1	5	p-S228,S402-PINK1 [mitochondrial outer membrane] (R-HSA-9834051) PINK1 [mitochondrial outer membrane] (R-HSA-5205653) PINK1 [mitochondrial intermembrane space] (R-HSA-5205671) PINK1 [cytosol] (R-HSA-5205637) PINK1(111-581) [mitochondrial intermembrane space] (R-HSA-5205628)	0.556	3
UniProt:P53350 PLK1	4	PLK1 [cytosol] (R-HSA-164603) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [nucleoplasm] (R-HSA-156720)	0.556	3
UniProt:P41227 NAA10			0.556	3
UniProt:Q07954-2 LRP1			0.556	3
IntAct:EBI-25853226 CCSB			0.556	3
UniProt:P43405 SYK	6	SYK [cytosol] (R-HSA-58268) p-Y348-SYK [cytosol] (R-HSA-437953) p-6Y-SYK [cytosol] (R-HSA-1861712) SYK [plasma membrane] (R-HSA-139844) p-Y-SYK [plasma membrane] (R-HSA-429432) p-Y-SYK [cytosol] (R-HSA-9705732)	0.556	3
UniProt:P62158 CALM			0.556	3
UniProt:Q9Y5B9 SUPT16H	1	SUPT16H [nucleoplasm] (R-HSA-112415)	0.556	3
UniProt:P17028 ZNF24			0.556	3
UniProt:P41236 IPP2			0.556	3
UniProt:P63000 RAC1	6	RAC1 [plasma membrane] (R-HSA-351141) RAC1 [cytosol] (R-HSA-442615) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802)	0.556	3
UniProt:Q96GM8 TOE1			0.556	3
IntAct:EBI-25935916 CCSB			0.556	3
UniProt:P22612 PRKACG	3	PRKACG [ciliary base] (R-HSA-5610405) PRKACG [cytosol] (R-HSA-57848) PRKACG [nucleoplasm] (R-HSA-111938)	0.556	3
UniProt:P20674 COX5A	2	COX5A [mitochondrial intermembrane space] (R-HSA-9865415) COX5A [mitochondrial inner membrane] (R-HSA-164308)	0.556	3
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.556	3
UniProt:Q9Y3C5 RNF11			0.556	3
UniProt:O15392 BIRC5	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.556	3
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.556	3
UniProt:O00213-2 APBB1			0.556	6
UniProt:P20226 TBP	1	TBP [nucleoplasm] (R-HSA-83718)	0.556	3
UniProt:Q15036 SNX17			0.556	3
UniProt:P00734 F2	11	thrombin light chain [extracellular region] (R-HSA-140598) thrombin heavy chain [extracellular region] (R-HSA-140589) 10xCbxE-F2(44-622) [extracellular region] (R-HSA-140674) 10xCbxE-F2(44-327) [extracellular region] (R-HSA-140786) thrombin light chain [plasma membrane] (R-HSA-140810) thrombin heavy chain [plasma membrane] (R-HSA-140809) F2(25-622) [endoplasmic reticulum lumen] (R-HSA-159739) 10xCbxE-F2(25-622) [endoplasmic reticulum lumen] (R-HSA-159800) 10xCbxE-F2(25-622) [Golgi lumen] (R-HSA-159841) 10xCbxE-F2(44-622) [Golgi lumen] (R-HSA-159845) prothrombin (factor II) propeptide [Golgi lumen] (R-HSA-159759)	0.556	3
UniProt:Q71U36 TUBA1A	9	TUBA1A [cytosol] (R-HSA-191689) TUBA1A [axonemal microtubule] (R-HSA-5610433) TUBA1A(1-450) [cytosol] (R-HSA-8955577) Polyglutamyl-TUBA1A [cytosol] (R-HSA-8867408) L-isoglutamyl polyglycyl-TUBA1A [cytosol] (R-HSA-8867428) TUBA1A unfolded [cytosol] (R-HSA-392767) TUBA1A folding intermediate [cytosol] (R-HSA-392805) Ac K40 TUBA1A [axonemal microtubule] (R-HSA-5624852) AcK-TUBA1A [cytosol] (R-HSA-5618312)	0.556	3
UniProt:P09429 HMGB1	5	HC23,45-HMGB1 [extracellular region] (R-HSA-6797422) HMGB1 [nucleoplasm] (R-HSA-266221) HMGB1 [extracellular region] (R-HSA-879382) HMGB1 [ficolin-1-rich granule lumen] (R-HSA-6803291) HMGB1 [secretory granule lumen] (R-HSA-6803337)	0.556	3
UniProt:P08473 MME	2	MME [secretory granule membrane] (R-HSA-6806156) MME [plasma membrane] (R-HSA-2022342)	0.556	3
UniProt:Q15172 PPP2R5A	2	p-S28-PPP2R5A [cytosol] (R-HSA-9836658) PPP2R5A [cytosol] (R-HSA-196235)	0.556	3
UniProt:Q16143 SNCB	1	SNCB [cytosol] (R-HSA-5660390)	0.556	3
UniProt:Q8WVK1 Q8WVK1			0.556	3
UniProt:P07384 CAPN1	4	CAPN1 [ficolin-1-rich granule lumen] (R-HSA-6801284) CAPN1 [extracellular region] (R-HSA-6806485) CAPN1 [cytosol] (R-HSA-3288367) CAPN1 [plasma membrane] (R-HSA-3828038)	0.556	3
UniProt:P10415 BCL2	1	BCL2 [mitochondrial outer membrane] (R-HSA-50757)	0.556	3
UniProt:O43508 TNFSF12	2	TNFSF12 [plasma membrane] (R-HSA-5667154) sTNFSF12 [extracellular region] (R-HSA-5675974)	0.556	3
UniProt:Q96BI3 APH1A	2	APH1A [plasma membrane] (R-HSA-3211581) APH1A [endosome membrane] (R-HSA-9010105)	0.556	3
UniProt:Q9NZR2 LRP1B			0.556	3
UniProt:Q8IUQ4-2 SIAH1			0.556	3
UniProt:P27986-2 PIK3R1			0.556	3
UniProt:O14576-5 O145765			0.556	3
UniProt:P43354 NR4A2	2	polySUMO2,3-K558,K577-NR4A2 [nucleoplasm] (R-HSA-4755517) NR4A2 [nucleoplasm] (R-HSA-376305)	0.556	3
UniProt:O14576-2 O145762			0.556	3
UniProt:Q9BTI6 Q9BTI6			0.556	3
UniProt:P00748 F12	11	factor XIIa light chain [extracellular region] (R-HSA-158320) factor XIIa heavy chain [extracellular region] (R-HSA-158285) factor XII [plasma membrane] (R-HSA-158214) F12 T328K [plasma membrane] (R-HSA-9653238) F12 T328R [plasma membrane] (R-HSA-9653226) F12 T328R(20-328) [extracellular region] (R-HSA-9653225) F12 T328K(20-328) [extracellular region] (R-HSA-9653230) F12 T328K (329-615) [extracellular region] (R-HSA-9653252) F12 T328R (329-615) [extracellular region] (R-HSA-9653243) F12 T328R (373-615) [extracellular region] (R-HSA-9655055) F12 T328K (373-615) [extracellular region] (R-HSA-9655053)	0.556	3
UniProt:P00749 PLAU	6	PLAU(21-431) [tertiary granule membrane] (R-HSA-6800974) PLAU(21-431) [plasma membrane] (R-HSA-158945) PLAU(21-431) [specific granule membrane] (R-HSA-6799705) PLAU(21-431) [extracellular region] (R-HSA-158979) PLAU(179-431) [plasma membrane] (R-HSA-158970) PLAU(21-177) [plasma membrane] (R-HSA-158956)	0.556	3
UniProt:O96013-2 PAK4			0.556	3
UniProt:Q16352 AINX			0.556	3
UniProt:P98082 DAB2	3	DAB2 [cytosol] (R-HSA-8862456) DAB2 [lysosomal membrane] (R-HSA-2980807) DAB2 [plasma membrane] (R-HSA-2980808)	0.556	3
UniProt:P67775 PPP2CA	4	PPP2CA [cytosol] (R-HSA-165971) PPP2CA [nucleoplasm] (R-HSA-165978) p-Y307-PPP2CA [cytosol] (R-HSA-8857939) MeL-PPP2CA [nucleoplasm] (R-HSA-8857791)	0.556	3
UniProt:O43752 STX6	2	STX6 [trans-Golgi network membrane] (R-HSA-6811007) STX6 [Golgi membrane] (R-HSA-6811004)	0.556	3
UniProt:P43681 CHRNA4	1	CHRNA4 [plasma membrane] (R-HSA-507836)	0.556	3
UniProt:O60333-2 KIF1B			0.556	3
UniProt:Q9BVJ6 UTP14A	1	UTP14A [nucleoplasm] (R-HSA-6790695)	0.556	3
UniProt:P08253 MMP2	5	MMP2(110-660) [extracellular region] (R-HSA-381456) MMP2(30-660) [extracellular region] (R-HSA-1604364) MMP2(30-66) [extracellular region] (R-HSA-1604347) MMP2(67-660) [extracellular region] (R-HSA-1604345) MMP2(67-109) [extracellular region] (R-HSA-1604371)	0.556	3
UniProt:Q99714-2 HSD17B10			0.556	3
UniProt:Q07866-2 KLC1			0.556	3
UniProt:I6L9F6 I6L9F6			0.556	6
UniProt:Q05586 GRIN1	3	GRIN1 [plasma membrane] (R-HSA-419564) GRIN1 [endoplasmic reticulum membrane] (R-HSA-9609763) GRIN1 [transport vesicle membrane] (R-HSA-9610565)	0.556	3
UniProt:P08247 SYP	1	SYP [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-5215991)	0.556	3
UniProt:O14656-2 TOR1A			0.556	3
UniProt:Q14031 COL4A6	20	3x4Hyp-GlcGalHyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2023654) 3x4Hyp-3Hyp-GlcGalHyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2023641) 3x4Hyp-3Hyp-GalHyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2023561) 3x4Hyp-GalHyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2023563) GlcGalHyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2023626) GalHyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2023535) COL4A6 [endoplasmic reticulum lumen] (R-HSA-1980196) 3x4Hyp-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2022125) 3x4Hyp-3Hyp-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2022486) 3x4Hyp-5Hyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2022979) 3x4Hyp-3Hyp-5Hyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2022969) 5Hyl-COL4A6 [endoplasmic reticulum lumen] (R-HSA-2022447) 5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region] (R-HSA-2682374) 3x4Hyp-3Hyp-COL4A6 [extracellular region] (R-HSA-2127313) 5Hyl-COL4A6 [extracellular region] (R-HSA-2127361) 3x4Hyp-3Hyp-GlcGalHyl-COL4A6 [extracellular region] (R-HSA-2127299) 3x4Hyp-COL4A6 [extracellular region] (R-HSA-2127333) 3x4Hyp-3Hyp-5Hyl-COL4A6 [extracellular region] (R-HSA-2127398) 3x4Hyp-GalHyl-COL4A6 [extracellular region] (R-HSA-2127370) GalHyl-COL4A6 [extracellular region] (R-HSA-2127354)	0.556	3
UniProt:Q15019-3 SEPTIN2			0.556	3
UniProt:P40763-2 STAT3			0.556	3
UniProt:Q9UNH7 SNX6			0.556	3
UniProt:Q03013 GSTM4	1	GSTM4 [cytosol] (R-HSA-3004516)	0.556	3
UniProt:Q9NZ42 PSENEN	2	PSENEN [plasma membrane] (R-HSA-157331) PSENEN [endosome membrane] (R-HSA-9010101)	0.556	3
UniProt:Q03135 CAV1	5	CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [early endosome membrane] (R-HSA-5368451) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009)	0.556	3
UniProt:Q96GW7 BCAN	20	D2,4,4(S)3-BCAN(361-911) [extracellular region] (R-HSA-3791190) CSE-BCAN(361-911) [extracellular region] (R-HSA-3791188) C6S-BCAN(361-911) [extracellular region] (R-HSA-3791186) C4S-BCAN(361-911) [extracellular region] (R-HSA-3791182) D2,4(S)2-BCAN(361-911) [extracellular region] (R-HSA-3791181) D4S-BCAN(361-911) [extracellular region] (R-HSA-3791193) D4S-BCAN(23-360) [extracellular region] (R-HSA-3791191) D2,4(S)2-BCAN(23-360) [extracellular region] (R-HSA-3791189) C6S-BCAN(23-360) [extracellular region] (R-HSA-3791184) D2,4,4(S)3-BCAN(23-360) [extracellular region] (R-HSA-3791180) C4S-BCAN(23-360) [extracellular region] (R-HSA-3791179) CSE-BCAN(23-360) [extracellular region] (R-HSA-3791192) D2,4(S)2-BCAN(23-395) [extracellular region] (R-HSA-3791174) D2,4,4(S)3-BCAN(23-395) [extracellular region] (R-HSA-3791127) C6S-BCAN(23-395) [extracellular region] (R-HSA-3791162) C4S-BCAN(23-395) [extracellular region] (R-HSA-3791130) D4S-BCAN(23-395) [extracellular region] (R-HSA-3791147) CSE-BCAN(23-395) [extracellular region] (R-HSA-3791131) C4S-BCAN(396-911) [extracellular region] (R-HSA-3791157) D2,4,4(S)3-BCAN(396-911) [extracellular region] (R-HSA-3791170)	0.556	3
UniProt:Q9UMF0 ICAM5	1	ICAM5 [plasma membrane] (R-HSA-197684)	0.556	3
UniProt:P49768-2 PSEN1			0.556	6
UniProt:Q9H270 VPS11	1	VPS11 [endosome membrane] (R-HSA-2197802)	0.556	3
UniProt:P46779 RPL28	1	RPL28 [cytosol] (R-HSA-72444)	0.556	3
UniProt:P56211 ARPP19	2	ARPP19 [nucleoplasm] (R-HSA-2160959) p-S62-ARPP19 [nucleoplasm] (R-HSA-2168081)	0.556	3
UniProt:Q15118 PDK1	1	PDK1 [mitochondrial matrix] (R-HSA-203944)	0.556	3
UniProt:P49757-8 NUMB			0.556	3
UniProt:Q96QK1 VPS35	1	VPS35 [cytosol] (R-HSA-3247740)	0.556	3
UniProt:P36507 MAP2K2	12	p-S222,S226-MAP2K2 [cytosol] (R-HSA-169292) MAP2K2 [cytosol] (R-HSA-59504) p-S,T-MAP2K2 [cytosol] (R-HSA-109848) MAP2K2 N126D [cytosol] (R-HSA-9652079) MAP2K2 L46F [cytosol] (R-HSA-9652076) MAP2K2 F57C [cytosol] (R-HSA-9652073) MAP2K2 Y134C [cytosol] (R-HSA-9652089) MAP2K2 V35M [cytosol] (R-HSA-9652086) MAP2K2 P128Q [cytosol] (R-HSA-9652082) MAP2K2 C125S [cytosol] (R-HSA-9652070) MAP2K2(11-400) [cytosol] (R-HSA-5211337) MAP2K2(1-10) [cytosol] (R-HSA-5211334)	0.556	3
UniProt:Q8IUW6 Q8IUW6			0.556	3
UniProt:Q01094 E2F1	2	E2F1 [nucleoplasm] (R-HSA-68639) p-E2F1 [nucleoplasm] (R-HSA-187911)	0.556	3
UniProt:Q6IAD4 Q6IAD4			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q15583 TGIF1	1	TGIF1 [nucleoplasm] (R-HSA-2186594)	0.556	3
UniProt:P31146 CORO1A	1	CORO1A [cytosol] (R-HSA-9636432)	0.556	3
UniProt:Q13190-4 STX5			0.556	3
UniProt:Q05655 PRKCD	12	PRKCD [cytosol] (R-HSA-58200) PRKCD(1-329) [cytosol] (R-HSA-212547) PRKCD(330-676) [cytosol] (R-HSA-212551) active p-T507,S645,S664-PRKCD [plasma membrane] (R-HSA-5607635) p-T507,S645,S664-PRKCD(1-676) [plasma membrane] (R-HSA-198294) p-T507,S645,S664-PRKCD [cytosol] (R-HSA-5218734) p-T507-PRKCD [cytosol] (R-HSA-5218746) PRKCD(330-676) [azurophil granule lumen] (R-HSA-6799221) PRKCD(1-329) [azurophil granule lumen] (R-HSA-6799219) PRKCD(1-329) [extracellular region] (R-HSA-6806226) PRKCD(330-676) [extracellular region] (R-HSA-6806199) PRKCD(1-676) [nucleoplasm] (R-HSA-450606)	0.556	3
UniProt:P20042 EIF2S2	1	EIF2S2 [cytosol] (R-HSA-72512)	0.556	6
UniProt:P54253 ATX1			0.556	8
UniProt:Q13155 AIMP2	1	AIMP2 [cytosol] (R-HSA-379576)	0.556	3
UniProt:O75553-4 DAB1			0.556	3
IntAct:EBI-25907740 CCSB			0.556	3
UniProt:Q9UQM7 CAMK2A	6	p-T286-CAMK2A [cytosol] (R-HSA-445368) CAMK2A [cytosol] (R-HSA-4332329) p-T286,T305,T306-CAMK2A [cytosol] (R-HSA-4332334) p-T286-CAMK2A [endocytic vesicle membrane] (R-HSA-416999) p-T286-CAMK2A [nucleoplasm] (R-HSA-444797) p-T286-CAMK2A [plasma membrane] (R-HSA-432796)	0.556	3
UniProt:O15162 PLS1			0.556	3
UniProt:Q02156 PRKCE	2	PRKCE [cytosol] (R-HSA-58202) p-T566,T710,S729-PRKCE [plasma membrane] (R-HSA-198260)	0.556	3
UniProt:P02743 APCS	1	APCS(20-223) [extracellular region] (R-HSA-976737)	0.556	3
UniProt:P43250 GRK6	1	GRK6 [plasma membrane] (R-HSA-8852159)	0.556	3
UniProt:Q6I9W9 Q6I9W9			0.556	3
UniProt:Q15109 AGER	1	AGER [plasma membrane] (R-HSA-197639)	0.556	3
UniProt:Q9UJY5-4 GGA1			0.556	3
UniProt:Q96A83-2 Q96A832			0.556	3
UniProt:P22694 PRKACB	3	PRKACB [nucleoplasm] (R-HSA-111937) PRKACB [cytosol] (R-HSA-57846) PRKACB [ciliary base] (R-HSA-5610404)	0.556	3
UniProt:Q15349 RPS6KA2	7	p-S218,T356,S360,S377,T570,T730-RPS6KA2 [nucleoplasm] (R-HSA-444290) p-T356,S360,S377,T570,T730-RPS6KA2 [cytosol] (R-HSA-9619984) p-S218,T356,S360,S377,T570,T730-RPS6KA2 [cytosol] (R-HSA-9619869) p-T356,S360,T570-RPS6KA2 [cytosol] (R-HSA-9619955) RPS6KA2 [cytosol] (R-HSA-444252) p-4S,T356,T570-RPS6KA2 [nucleoplasm] (R-HSA-199871) RPS6KA2 [nucleoplasm] (R-HSA-199861)	0.556	3
UniProt:P83916 CBX1	1	CBX1 [nucleoplasm] (R-HSA-9653629)	0.556	6
UniProt:P07948 LYN	7	LYN [cytosol] (R-HSA-354251) MyrG2-PalmC3-LYN [plasma membrane] (R-HSA-9606875) p-Y397-LYN [plasma membrane] (R-HSA-2454229) p-Y397-LYN [cytosol] (R-HSA-8942608) LYN [plasma membrane] (R-HSA-197943) MyrG2-PalmC3-LYN [endocytic vesicle membrane] (R-HSA-9705728) MyrG2-PalmC3-LYN [lysosomal membrane] (R-HSA-9707903)	0.556	3
UniProt:P25098 GRK2	4	GRK2 [plasma membrane] (R-HSA-50270) p-S29-ADRBK1 [plasma membrane] (R-HSA-111969) ADRBK1 [cilium] (R-HSA-5632504) p-S29-ADRBK1 [cytosol] (R-HSA-9645318)	0.556	3
UniProt:P84022 SMAD3	20	p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-177104) p-S423,S425-SMAD3 [cytosol] (R-HSA-171184) SMAD3 [cytosol] (R-HSA-170855) p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-2176471) Ub,p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-9773841) 2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-2187326) SMAD3 [nucleoplasm] (R-HSA-206150) p-S208-SMAD3 [cytosol] (R-HSA-9731114) SMAD3 S425C [cytosol] (R-HSA-3308499) SMAD3 Y298* [cytosol] (R-HSA-9668769) SMAD3 R368* [cytosol] (R-HSA-9668768) SMAD3 E383* [cytosol] (R-HSA-9668775) SMAD3 S425F [cytosol] (R-HSA-8944158) SMAD3 Q322* [cytosol] (R-HSA-9668773) SMAD3 Q358* [cytosol] (R-HSA-9668772) SMAD3 E246* [cytosol] (R-HSA-9668776) SMAD3 W326* [cytosol] (R-HSA-9668766) SMAD3 Y384* [cytosol] (R-HSA-9668782) SMAD3 Q316* [cytosol] (R-HSA-9668765) p-S423,S425-SMAD3 R268H [cytosol] (R-HSA-3315080)	0.556	3
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.556	3
UniProt:Q6ZW49 PAXIP1	1	PAXIP1 [nucleoplasm] (R-HSA-5619395)	0.556	3
UniProt:P51572 BCAP31	6	BCAP31 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985503) BCAP31 [endoplasmic reticulum membrane] (R-HSA-9714333) BCAP31(2-245) [endoplasmic reticulum membrane] (R-HSA-201587) BCAP31(165-237) [endoplasmic reticulum membrane] (R-HSA-351909) BCAP31(2-164) [endoplasmic reticulum membrane] (R-HSA-351826) BCAP31(238-246) [cytosol] (R-HSA-351912)	0.556	3
UniProt:P99999 CYCS	6	CYCS [cytosol] (R-HSA-53259) CYCS [mitochondrial intermembrane space] (R-HSA-114244) apo-CYCS [mitochondrial inner membrane] (R-HSA-352608) Cytochrome c (reduced) [mitochondrial inner membrane] (R-HSA-352609) Cytochrome c (oxidised) [mitochondrial inner membrane] (R-HSA-352607) AcK-CYCS [mitochondrial intermembrane space] (R-HSA-5688308)	0.556	3
UniProt:P04271 S100B	1	S100B [extracellular region] (R-HSA-879433)	0.556	3
UniProt:P06493 CDK1	11	p-T161-CDK1 [nucleoplasm] (R-HSA-170066) p-T14,Y15,T161-CDK1 [nucleoplasm] (R-HSA-170074) p-T161-CDK1 [cytosol] (R-HSA-157415) p-T14,Y15,T161-CDK1 [cytosol] (R-HSA-170071) CDK1 [cytosol] (R-HSA-170075) CDK1 [nucleoplasm] (R-HSA-68889) p-T14-CDK1 [cytosol] (R-HSA-170064) p-T14-CDK1 [nucleoplasm] (R-HSA-170045) p-T14,T161-CDK1 [nucleoplasm] (R-HSA-170078) p-Y4-CDK1 [cytosol] (R-HSA-9836187) CDK1 [endoplasmic reticulum membrane] (R-HSA-264424)	0.556	3
UniProt:Q14289 PTK2B	3	PTK2B [cytosol] (R-HSA-5218721) PTK2B [cytosol] (R-HSA-390932) p-Y-PTK2B [cytosol] (R-HSA-508515)	0.556	3
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.556	3
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.556	3
UniProt:Q9NPC7 MYNN			0.553	2
UniProt:Q8WTR7 ZNF473	1	ZNF473 [nucleoplasm] (R-HSA-1247861)	0.553	2
UniProt:Q86T29 ZNF605	1	ZNF605 [nucleoplasm] (R-HSA-2127592)	0.553	2
UniProt:Q6AZW8 ZNF660	1	ZNF660 [nucleoplasm] (R-HSA-2248875)	0.553	2
UniProt:Q86WZ6 ZNF227	1	ZNF227 [nucleoplasm] (R-HSA-1027397)	0.553	2
UniProt:Q8N2I2 ZNF619	1	ZNF619 [nucleoplasm] (R-HSA-2127581)	0.553	2
UniProt:P52736 ZNF133	1	ZNF133 [nucleoplasm] (R-HSA-975036)	0.553	2
UniProt:Q8IVC4 ZNF584	1	ZNF584 [nucleoplasm] (R-HSA-2127568)	0.553	2
UniProt:Q5SW96 LDLRAP1	2	LDLRAP1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869097) LDLRAP1 [plasma membrane] (R-HSA-171143)	0.553	2
UniProt:Q9NR11 ZNF302	1	ZNF302 [nucleoplasm] (R-HSA-1027433)	0.553	2
UniProt:Q92905 COPS5	2	COPS5 [nucleoplasm] (R-HSA-5697019) COPS5 [cytosol] (R-HSA-416963)	0.553	2
UniProt:O14709 ZNF197	1	ZNF197 [nucleoplasm] (R-HSA-975032)	0.553	2
UniProt:Q9GZU2 PEG3			0.553	2
UniProt:Q13642 FHL1			0.553	2
UniProt:Q9NR48 ASH1L	1	ASH1L [nucleoplasm] (R-HSA-1183218)	0.553	2
UniProt:O43257 ZNHI1			0.553	2
UniProt:Q8WXB4 ZNF606	1	ZNF606 [nucleoplasm] (R-HSA-2127593)	0.553	2
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.553	2
UniProt:Q5VT06 CE350			0.553	2
UniProt:Q9NQX6 ZNF331	1	ZNF331 [nucleoplasm] (R-HSA-1247549)	0.553	2
UniProt:Q3L8U1 CHD9	1	CHD9 [nucleoplasm] (R-HSA-400163)	0.553	2
UniProt:Q6ZNA1 ZN836			0.553	2
UniProt:O60315 ZEB2	1	ZEB2 [nucleoplasm] (R-HSA-3108222)	0.553	2
UniProt:O60673 REV3L	1	REV3L [nucleoplasm] (R-HSA-110278)	0.553	2
UniProt:Q5XPI4 RNF123	2	K63polyUb-RNF123 [cytosol] (R-HSA-6783055) RNF123 [cytosol] (R-HSA-975996)	0.553	2
UniProt:Q92664 GTF3A	1	GTF3A [nucleoplasm] (R-HSA-65892)	0.553	2
UniProt:Q9NZL3 ZNF224	1	ZNF224 [nucleoplasm] (R-HSA-1027352)	0.553	2
UniProt:P21675 TAF1	1	TAF1 [nucleoplasm] (R-HSA-65539)	0.553	2
UniProt:Q2M3W8 ZN181			0.553	2
UniProt:Q15154 PCM1	1	PCM1 [cytosol] (R-HSA-380308)	0.553	2
UniProt:Q8TBJ5 FEZF2			0.553	2
UniProt:Q8N9K5 ZNF565	1	ZNF565 [nucleoplasm] (R-HSA-1973890)	0.553	2
UniProt:Q9HCZ1 ZNF334	1	ZNF334 [nucleoplasm] (R-HSA-1247515)	0.553	2
UniProt:Q96ND8 ZNF583	1	ZNF583 [nucleoplasm] (R-HSA-2127583)	0.553	2
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.553	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:O95243 MBD4	1	MBD4 [nucleoplasm] (R-HSA-3006633)	0.553	2
UniProt:P82933 MRPS9	1	MRPS9 [mitochondrial inner membrane] (R-HSA-5368194)	0.553	2
UniProt:Q2M1K9 ZNF423	1	ZNF423 [nucleoplasm] (R-HSA-3222318)	0.553	2
UniProt:Q9H0D6 XRN2	2	XRN2 [nucleoplasm] (R-HSA-6791205) XRN2 [cytosol] (R-HSA-391297)	0.553	2
UniProt:P15253 CALR			0.544	3
UniProt:Q306T3 Q306T3			0.544	3
UniProt:P46933	1	Apbb1 [nucleoplasm] (R-RNO-5683987)	0.528	2
UniProt:P01100 FOS	2	FOS [nucleoplasm] (R-HSA-450216) p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283)	0.524	3
UniProt:P61457 PCBD1	1	PCBD1 [cytosol] (R-HSA-71131)	0.524	2
UniProt:Q9CR16 PPID			0.508	3
UniProt:P21359 NF1	20	NF1 R816* [cytosol] (R-HSA-6802424) NF1 F1464L [cytosol] (R-HSA-6802410) NF1 K1444E [cytosol] (R-HSA-6802414) NF1 L1187I [cytosol] (R-HSA-6802417) NF1 R1276P [cytosol] (R-HSA-6802420) NF1 R1412S [cytosol] (R-HSA-6802421) NF1 R2517* [cytosol] (R-HSA-9647532) NF1 Q616Gfs4 [cytosol] (R-HSA-9647468) NF1 R2450 [cytosol] (R-HSA-9647535) NF1 R2637* [cytosol] (R-HSA-9647529) NF1 R2637Q [cytosol] (R-HSA-9647525) NF1 R304* [cytosol] (R-HSA-9647522) NF1 R1276* [cytosol] (R-HSA-9647550) NF1 C845Vfs33 [cytosol] (R-HSA-9647486) NF1(2-2839) [cytosol] (R-HSA-947770) ub-NF1(2-2839) [cytosol] (R-HSA-5658418) NF1 R69Nfs7 [cytosol] (R-HSA-9647505) NF1 R440* [cytosol] (R-HSA-9647511) NF1 R440Q [cytosol] (R-HSA-9647508) NF1 G849E fs*29 [cytosol] (R-HSA-9656596)	0.508	3
UniProt:P78352 DLG4	3	DLG4 [plasma membrane] (R-HSA-202135) DLG4 [endocytic vesicle membrane] (R-HSA-416847) DLG4 [cytosol] (R-HSA-6794267)	0.499	2
UniProt:P56817-1 BACE1			0.489	2
UniProt:Q99683 MAP3K5	1	MAP3K5 [cytosol] (R-HSA-167709)	0.483	2
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.483	2
UniProt:O14879 IFIT3	1	IFIT3 [cytosol] (R-HSA-947491)	0.482	2
UniProt:Q99720 SIGMAR1	1	SIGMAR1 [cytosol] (R-HSA-9679757)	0.462	3
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	2
UniProt:Q15392 DHCR24	1	DHCR24 [endoplasmic reticulum membrane] (R-HSA-196414)	0.462	3

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