Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GIPC1 [cytoplasm]
Stable Identifier
R-HSA-9839329
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytoplasm
Synonyms
PDZ domain-containing protein GIPC1, GIPC1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P06463 VE6
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGFBR3 (Homo sapiens)
TGFBR3 regulates FGF2 signaling (Homo sapiens)
FGF2:TGFBR3 binding to GIPC1 (Homo sapiens)
GIPC1 [cytoplasm] (Homo sapiens)
TGFBR3 regulates TGF-beta signaling (Homo sapiens)
TGFBR3 binding to GIPC1 (Homo sapiens)
GIPC1 [cytoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14908 GIPC1
Gene Names
GIPC1, C19orf3, GIPC, RGS19IP1
Chain
chain:1-333
Reference Genes
COSMIC (genes):GIPC1 GIPC1
dbSNP Gene:10755 GIPC1
ENSEMBL:ENSG00000123159 GIPC1
Participates
as a component of
TGFB1,TGFB2:TGFBR3:GIPC1 [cytoplasmic side of plasma membrane] (Homo sapiens)
FGF2:TGFBR3:GIPC1 [plasma membrane] (Homo sapiens)
as an input of
TGFBR3 binding to GIPC1 (Homo sapiens)
FGF2:TGFBR3 binding to GIPC1 (Homo sapiens)
Inferred To
Gipc1 [cytoplasm]
(Mus musculus)
Gipc1 [cytoplasm]
(Rattus norvegicus)
GIPC1 [cytoplasm]
(Canis familiaris)
GIPC1 [cytoplasm]
(Gallus gallus)
GIPC1 [cytoplasm]
(Sus scrofa)
gipc1 [cytoplasm]
(Danio rerio)
gipc1 [cytoplasm]
(Xenopus tropicalis)
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9P0V3 SH3BP4
1
SH3BP4 [cytosol]
(R-HSA-8866227)
0.736
5
UniProt:Q9NZN5 ARHGEF12
1
ARHGEF12 [cytosol]
(R-HSA-416560)
0.723
8
UniProt:Q9UM54 MYO6
3
MYO6 [plasma membrane]
(R-HSA-3006691)
MYO6 [lysosomal membrane]
(R-HSA-3006694)
MYO6 [cytosol]
(R-HSA-3006692)
0.688
3
UniProt:P06463 VE6
0.581
3
UniProt:Q9HB19 PLEKHA2
1
PLEKHA2 [plasma membrane]
(R-HSA-8870329)
0.556
3
UniProt:P17643 TYRP1
1
TYRP1 [melanosome membrane]
(R-HSA-8878574)
0.508
3
UniProt:Q03167 TGFBR3
5
pT841_TGFBR3 [plasma membrane]
(R-HSA-9839364)
TGFBR3 [cytosol]
(R-HSA-9839374)
TGFBR3(784-851) [basolateral plasma membrane]
(R-HSA-9839380)
TGFBR3(1-783) [extracellular region]
(R-HSA-9839335)
TGFBR3_mem [plasma membrane]
(R-HSA-9839336)
0.508
3
UniProt:Q9UKG1 APPL1
1
APPL1 [endosome membrane]
(R-HSA-373630)
0.483
3
UniProt:Q8TF65 GIPC2
0.483
2
UniProt:Q9C0C4 SEM4C
0.483
2
UniProt:Q8NEU8 DP13B
0.483
3
UniProt:Q9BWT7 CAR10
0.482
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text