TGFBR3 regulates FGF2 signaling

Stable Identifier
R-HSA-9839397
Type
Pathway
Species
Homo sapiens
ReviewStatus
3/5
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TGFBR3 regulates FGF2 signaling
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This subpathway describes the regulation of FGF2:FGFR1 mediated signaling by the TGFBR3 receptor complex. TGFBR3 have binding affinity for FGF2 (Andres et al., 1992) and in presence of GIPC, FGF2/TGFBR3/GPIC enhances FGF2 signaling (Knelson et al.,2013).
Literature References
PubMed ID Title Journal Year
1556106 Binding of two growth factor families to separate domains of the proteoglycan betaglycan

DeFalcis, D, Noda, M, Massagué, J, Andres, JL

J Biol Chem 1992
24216509 Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma

Mythreye, K, Blobe, GC, Armstrong, MB, Gaviglio, AL, Tewari, AK, Knelson, EH

J Clin Invest 2013
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
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