Reactome | ALKAL1 [extracellular region]

ALKAL1 [extracellular region]

Stable Identifier

R-HSA-9842576

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

FAM150A, fullName evidence="13 14"ALK and LTK ligand 1, ALKL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6UXT8 FAM150A

Gene Names

FAM150A, UNQ9433/PRO34745, ALKAL1

Chain

signal peptide:1-27, chain:28-129

Reference Genes

BioGPS Gene:389658 FAM150A

COSMIC (genes):ALKAL1 FAM150A

CTD Gene:389658 FAM150A

dbSNP Gene:389658 FAM150A

ENSEMBL:ENSG00000196711 FAM150A

HGNC:33775 FAM150A

Monarch:389658 FAM150A

NCBI Gene:389658 FAM150A

OMIM:619670 FAM150A

UCSC:Q6UXT8 FAM150A

Reference Transcript

RefSeq:NM_207413.3 FAM150A

Other Identifiers

11737645_a_at

17077128

3135170

3135171

3135172

3135174

3135181

3135182

389658

8150751

A_24_P935794

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0007169

GO:0010976

GO:0030297

GO:0030298

GO:0030971

GO:0048018

GO:0070374

GO:0070378

GO:0098772

HMNXSV003026998

ILMN_1753933

ILMN_2091217

PH_hs_0034586

TC08001209.hg

Participates

as a candidate of

ALKAL2:(ALKAL1) [extracellular region] (Homo sapiens)

as a member of

ALKAL1,2 [extracellular region] (Homo sapiens)

Inferred To

alkal1 [extracellular region] (Danio rerio)

alkal1 [extracellular region] (Xenopus tropicalis)

Alkal1 [extracellular region] (Mus musculus)

Alkal1 [extracellular region] (Rattus norvegicus)

ALKAL1 [extracellular region] (Canis familiaris)

ALKAL1 [extracellular region] (Sus scrofa)

Cross References

ENSEMBL

ENST00000358543, ENSP00000351345, ENST00000523939, ENSP00000430953

OpenTargets

ENSG00000196711

HPA

ENSG00000196711-ALKAL1

PRO

Q6UXT8

Pharos - Targets

Q6UXT8

GlyGen

Q6UXT8

PDB

7MZZ, 7NX0, 7MK7

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UM73 ALK	20	p-7Y ALK T1087I [plasma membrane] (R-HSA-9723885) p-7Y ALK R1061Q [plasma membrane] (R-HSA-9723884) p-7Y ALK L1196M [plasma membrane] (R-HSA-9700464) p-7Y ALK M1166R [plasma membrane] (R-HSA-9700477) p-Y ALK S1206C [plasma membrane] (R-HSA-9715292) p- 7Y ALK L1122V [plasma membrane] (R-HSA-9715294) p-7Y ALK E1384K [plasma membrane] (R-HSA-9715285) p-7Y ALK L1196Q [plasma membrane] (R-HSA-9700476) p-7Y ALK V1180L [plasma membrane] (R-HSA-9715289) p-7Y ALK G1201R [plasma membrane] (R-HSA-9701860) p-7Y ALK I1171T [plasma membrane] (R-HSA-9700489) p-7Y ALK R1275L [plasma membrane] (R-HSA-9699800) p-7Y ALK F1174C [plasma membrane] (R-HSA-9699821) p-7Y ALK F1174V [plasma membrane] (R-HSA-9699921) p-7Y ALK M1166N [plasma membrane] (R-HSA-9723299) p-7Y ALK M1166T [plasma membrane] (R-HSA-9700486) p-7Y ALK Y1239H [plasma membrane] (R-HSA-9715290) p-7Y ALK R1275* [plasma membrane] (R-HSA-9699915) p-7Y ALK I1171S [plasma membrane] (R-HSA-9714063) p-7Y ALK G1128S [plasma membrane] (R-HSA-9700462)	0.655	7
UniProt:P29376 LTK	2	p-6Y-LTK [plasma membrane] (R-HSA-9842578) LTK [plasma membrane] (R-HSA-9842564)	0.591	3

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