Reactome: A Curated Pathway Database

Kinesin-8 is a dimer

Stable Identifier
R-HSA-984609
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Kinesin-8 is a plus-end-directed dimeric kinesin with an internal motor domain (Loughlin et al. 2008) that can depolymerize stable microtubuless specifically at their plus-ends (Pereira et al. 1997) in a length-dependent manner (Varga et al. 2006). Human kinesin-8 KIF18A is believed to promote chromosome congression by attenuating chromosome oscillation magnitudes (Stumpff et al. 2008).

Literature References
Participants
Participant Of
hasEvent
Inferred From