Reactome | KIF22 [cytosol]

KIF22 [cytosol]

Stable Identifier

R-HSA-984764

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Kinesin-like protein KIF22, KIF22_HUMAN, KID

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
    - Golgi-to-ER retrograde transport (Homo sapiens)
      - COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Chromokinesin dimers [cytosol] (Homo sapiens)
        
        Kinesin-10 [cytosol] (Homo sapiens)
        
        KIF22 [cytosol] (Homo sapiens)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Chromokinesin dimers [cytosol] (Homo sapiens)
        
        Kinesin-10 [cytosol] (Homo sapiens)
        
        KIF22 [cytosol] (Homo sapiens)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Chromokinesin dimers [cytosol] (Homo sapiens)
        
        Kinesin-10 [cytosol] (Homo sapiens)
        
        KIF22 [cytosol] (Homo sapiens)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Chromokinesin dimers [cytosol] (Homo sapiens)
        
        Kinesin-10 [cytosol] (Homo sapiens)
        
        KIF22 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14807 KIF22

Gene Names

KIF22, KID, KNSL4

Chain

chain:1-665

Reference Genes

BioGPS Gene:3835 KIF22

COSMIC (genes):KIF22 KIF22

CTD Gene:3835 KIF22

dbSNP Gene:3835 KIF22

ENSEMBL:ENSG00000079616 KIF22

HGNC:6391 KIF22

KEGG:hsa:3835 KIF22

Monarch:3835 KIF22

NCBI Gene:3835 KIF22

OMIM:603213 KIF22

UCSC:Q14807 KIF22

Reference Transcript

Other Identifiers

11728673_s_at

11751755_a_at

11756368_s_at

16817647

202183_PM_s_at

202183_s_at

216969_PM_s_at

216969_s_at

356_at

3655629

3655630

3655631

3655632

3655633

3655634

3655635

3655636

3655637

3655638

3655639

3655640

3655641

3655642

3655643

3655644

3655645

3655646

3655647

3655648

3655649

3655650

3655651

3655652

3655653

3655654

3655655

3655656

3655657

3655658

3655659

3655660

3655661

3655662

3655663

3655664

3655666

3655667

3655668

3655669

3655670

3655671

3835

7994620

8003583

A_14_P126702

A_23_P54622

A_33_P3350634

A_33_P3350638

D38751_at

GE53427

GO:0000278

GO:0000776

GO:0000785

GO:0003677

GO:0003774

GO:0003777

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005819

GO:0005829

GO:0005856

GO:0005871

GO:0005874

GO:0006281

GO:0007017

GO:0007018

GO:0007062

GO:0007080

GO:0008017

GO:0008092

GO:0016607

GO:0016787

GO:0016887

GO:0043226

GO:0051310

GO:0072686

GO:0140657

HMNXSV003000439

HMNXSV003008834

Hs.119324.1.S1_3p_a_at

ILMN_1814589

PH_hs_0006588

TC16000327.hg

g6453817_3p_a_at

Participates

as a member of

Chromokinesin monomers [cytosol] (Homo sapiens)

as a component of

Kinesin-10 [cytosol] (Homo sapiens)

Inferred To

KIF22 [cytosol] (Bos taurus)

KIF22 [cytosol] (Canis familiaris)

KIF22 [cytosol] (Sus scrofa)

kif22 [cytosol] (Danio rerio)

kif22 [cytosol] (Xenopus tropicalis)

Kif22 [cytosol] (Mus musculus)

Kif22 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_001243199.1, NP_001243198.1, NP_015556.1

ENSEMBL

ENSP00000160827, ENST00000561482, ENSP00000454957, ENSG00000079616, ENST00000400751, ENST00000690258, ENSP00000383562, ENST00000160827, ENSP00000509977

OpenTargets

ENSG00000079616

GeneCards

KIF22

HPA

ENSG00000079616-KIF22

PRO

Q14807

Pharos - Targets

Q14807

GlyGen

Q14807

Orphanet

KIF22

PDB

2EDU, 6NJE

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TC07 TBC1D15	1	TBC1D15 [cytosol] (R-HSA-8854150)	0.527	4