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BCAP31 [lumenal side of endoplasmic reticulum membrane]
Stable Identifier
R-HSA-985503
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lumenal side of endoplasmic reticulum membrane
Synonyms
BAP31
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Homo sapiens)
Antigen peptide bound class I MHC:BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of peptide loading complex (PLC) (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Loading of antigenic peptides on to class I MHC (Homo sapiens)
Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Transport of MHC heterotrimer to ER exit site (Homo sapiens)
Antigen peptide bound class I MHC:BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
BCAP31 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51572 BCAP31
Gene Names
BCAP31, BAP31, DXS1357E
Chain
initiator methionine:, chain:2-246
Reference Genes
BioGPS Gene:10134 BCAP31
COSMIC (genes):BCAP31 BCAP31
CTD Gene:10134 BCAP31
dbSNP Gene:10134 BCAP31
ENSEMBL:ENSG00000185825 BCAP31
HGNC:16695 BCAP31
KEGG:hsa:10134 BCAP31
Monarch:10134 BCAP31
NCBI Gene:10134 BCAP31
OMIM:300398 BCAP31
UCSC:P51572 BCAP31
Reference Transcript
RefSeq:NM_005745.7 BCAP31
RefSeq:NM_001139457.2 BCAP31
RefSeq:NM_001139441.1 BCAP31
RefSeq:NM_001256447.1 BCAP31
Other Identifiers
10134
11715422_a_at
11715423_s_at
11715424_x_at
11741191_a_at
17115207
17121378
17121380
17121504
200837_PM_at
200837_at
3657757
3657759
3657761
3657762
3657765
3658174
3658176
3658177
3658178
3658181
3689503
3689504
3689506
3689508
4026666
4026668
4026670
4026671
4026672
4026673
4026674
4026675
4026676
4026677
4026678
4026681
4026682
4026683
4026688
4026689
4026690
4026691
4026693
4026694
4026695
4026696
4026697
4026698
4026699
4026700
4026701
4026702
4026703
4026704
4026705
4026706
41724_at
75139_s_at
8175835
A_24_P134683
GE80206
GO:0000139
GO:0005515
GO:0005783
GO:0005789
GO:0005811
GO:0005829
GO:0005886
GO:0006626
GO:0006886
GO:0006888
GO:0006915
GO:0007283
GO:0012501
GO:0015031
GO:0016020
GO:0016192
GO:0022414
GO:0030136
GO:0031410
GO:0032580
GO:0033116
GO:0034976
GO:0042288
GO:0043226
GO:0044233
GO:0044877
GO:0070973
GO:0097038
GO:0098553
GO:1904154
GO:1904294
GO:2000060
GO:2001244
HMNXSV003014085
ILMN_1812403
PH_hs_0024339
TC0X001516.hg
TC0X002285.hg
X81817_at
g10047078_3p_at
Participates
as a repeated unit of
BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
BCAP31 [endoplasmic reticulum membrane]
BCAP31(2-245) [endoplasmic reticulum membrane]
BCAP31(165-237) [endoplasmic reticulum membrane]
BCAP31(2-164) [endoplasmic reticulum membrane]
BCAP31(238-246) [cytosol]
Inferred To
4D656 [lumenal side of endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Bcap31 [lumenal side of endoplasmic reticulum membrane]
(Mus musculus)
Bcap31 [lumenal side of endoplasmic reticulum membrane]
(Rattus norvegicus)
BCAP31 [lumenal side of endoplasmic reticulum membrane]
(Bos taurus)
BCAP31 [lumenal side of endoplasmic reticulum membrane]
(Canis familiaris)
BCAP31 [lumenal side of endoplasmic reticulum membrane]
(Dictyostelium discoideum)
BCAP31 [lumenal side of endoplasmic reticulum membrane]
(Gallus gallus)
BCAP31 [lumenal side of endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
BCAP31 [lumenal side of endoplasmic reticulum membrane]
(Sus scrofa)
Dmel\CG13887 [lumenal side of endoplasmic reticulum membrane]
(Drosophila melanogaster)
bcap31 [lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
bcap31 [lumenal side of endoplasmic reticulum membrane]
(Xenopus tropicalis)
YET3 [lumenal side of endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001132913.1
,
NP_005736.3
,
NP_001243376.1
,
NP_001132929.1
ENSEMBL
ENST00000458587
,
ENSP00000494052
,
ENSP00000392330
,
ENST00000345046
,
ENST00000647529
,
ENSP00000499882
,
ENSP00000343458
,
ENST00000672675
OpenTargets
ENSG00000185825
HPA
ENSG00000185825-BCAP31
PRO
P51572
Pharos - Targets
P51572
GlyGen
P51572
Orphanet
BCAP31
PDB
4JZL
,
4JZP
,
8XWX
Interactors (21)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UHQ4 BAP29
0.669
4
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
4
UniProt:Q77YB1 Q77YB1
0.645
6
UniProt:P60468 SEC61B
3
SEC61B [cytosol]
(R-HSA-5250571)
SEC61B [endoplasmic reticulum membrane]
(R-HSA-264899)
SEC61B [phagocytic vesicle membrane]
(R-HSA-1236882)
0.602
7
UniProt:Q15629 TRAM1
1
TRAM1 [endoplasmic reticulum membrane]
(R-HSA-265084)
0.602
5
UniProt:Q9Y3D6 FIS1
2
FIS1 [peroxisomal membrane]
(R-HSA-9033123)
FIS1 [cytosol]
(R-HSA-9033099)
0.599
8
UniProt:Q14790 CASP8
8
CASP8(1-374) [cytosol]
(R-HSA-3465404)
CASP8(217-374) [mitochondrial outer membrane]
(R-HSA-351869)
CASP8(385-479) [mitochondrial outer membrane]
(R-HSA-351828)
CASP8(385-479) [cytosol]
(R-HSA-76158)
CASP8(375-384) [cytosol]
(R-HSA-933460)
CASP8(217-374) [cytosol]
(R-HSA-75975)
CASP8(1-216) [cytosol]
(R-HSA-933456)
CASP8(1-479) [cytosol]
(R-HSA-57031)
0.589
3
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.583
9
UniProt:Q8CIE6
4
Copa [endoplasmic reticulum membrane]
(R-MMU-6810953)
Copa [Golgi membrane]
(R-MMU-6808731)
Copa [transport vesicle]
(R-MMU-6808732)
Copa [cytosol]
(R-MMU-199978)
0.564
2
UniProt:Q92876 KLK6
0.556
3
IntAct:EBI-10178693 9721
0.556
3
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.556
3
IntAct:EBI-22326698 CCSB ORF ID
0.556
3
UniProt:Q9NPL8 TIMMDC1
1
TIMMDC1 [mitochondrial inner membrane]
(R-HSA-5689720)
0.556
3
UniProt:P0DTD8 NS7B
0.547
2
UniProt:Q6Y1H2 HACD2
1
PTPLB [endoplasmic reticulum membrane]
(R-HSA-5676075)
0.543
4
UniProt:Q9BSL1 UBAC1
1
UBAC1 [cytosol]
(R-HSA-8851644)
0.527
2
UniProt:Q9Y3E0 GOT1B
0.527
2
UniProt:Q9NY72 SCN3B
1
SCN3B [plasma membrane]
(R-HSA-197921)
0.527
3
UniProt:P10415 BCL2
1
BCL2 [mitochondrial outer membrane]
(R-HSA-50757)
0.524
2
UniProt:Q9BUN8 DERL1
1
DERL1 [endoplasmic reticulum membrane]
(R-HSA-6781898)
0.499
3
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