Reactome | COQ8A [mitochondrial inner membrane]

COQ8A [mitochondrial inner membrane]

Stable Identifier

R-HSA-9856284

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ADCK3

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8NI60 COQ8A

Gene Names

COQ8A, ADCK3, CABC1, PP265

Chain

transit peptide:1-162, chain:163-647

Reference Genes

BioGPS Gene:56997 COQ8A

COSMIC (genes):COQ8A COQ8A

CTD Gene:56997 COQ8A

dbSNP Gene:56997 COQ8A

ENSEMBL:ENSG00000163050 COQ8A

HGNC:16812 COQ8A

KEGG:hsa:56997 COQ8A

Monarch:56997 COQ8A

NCBI Gene:56997 COQ8A

OMIM:606980 COQ8A

UCSC:Q8NI60 COQ8A

Reference Transcript

Other Identifiers

11732135_a_at

11747618_a_at

11747732_a_at

16678191

218168_PM_s_at

218168_s_at

222542_PM_x_at

222542_x_at

2383379

2383380

2383381

2383382

2383389

2383390

2383391

2383392

2383393

2383394

2383395

2383396

2383403

2383404

2383407

2383408

2383409

2383410

2383411

2383412

2383413

2383414

2383415

2383416

2383417

2383418

2383419

2383420

2383421

2383422

2383424

2383425

45334_at

56997

7910164

A_14_P124660

A_23_P85598

GE88281

GO:0003824

GO:0005515

GO:0005524

GO:0005739

GO:0006744

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0043226

GO:0043531

HMNXSV003053299

Hs.273186.0.S1_3p_a_at

ILMN_1731064

PH_hs_0014100

g9910387_3p_a_at

Participates

as a member of

COQ8A,B [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Q29RI0 [mitochondrial inner membrane] (Bos taurus)

P27697 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Q54IH6 [mitochondrial inner membrane] (Dictyostelium discoideum)

Q60936 [mitochondrial inner membrane] (Mus musculus)

Coq8 [mitochondrial inner membrane] (Drosophila melanogaster)

Q18486 [mitochondrial inner membrane] (Caenorhabditis elegans)

COQ8A [mitochondrial inner membrane] (Canis familiaris)

COQ8A [mitochondrial inner membrane] (Gallus gallus)

COQ8A [mitochondrial inner membrane] (Sus scrofa)

coq8a [mitochondrial inner membrane] (Xenopus tropicalis)

Q5RGU1 [mitochondrial inner membrane] (Danio rerio)

Q5BJQ0 [mitochondrial inner membrane] (Rattus norvegicus)

abc1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

Cross References

Guide to Pharmacology - Targets

1927

ENSEMBL

ENSG00000163050, ENSP00000355739, ENST00000366777, ENST00000366778, ENSP00000355740

OpenTargets

ENSG00000163050

GeneCards

COQ8A

HPA

ENSG00000163050-COQ8A

ZINC target

Q8NI60

PRO

Q8NI60

Pharos - Targets

Q8NI60

Orphanet

COQ8A

PDB

7UDQ, 4PED, 7UDP, 5I35

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.849	13
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:Q9H0Y0 ATG10	2	GlyK166-ATG10 [cytosol] (R-HSA-5683572) ATG10 [cytosol] (R-HSA-5671733)	0.556	3
UniProt:O60906 SMPD2	1	SMPD2 [plasma membrane] (R-HSA-194337)	0.556	3
UniProt:Q8WTS1 ABHD5	2	ABHD5 [lipid droplet] (R-HSA-163485) ABHD5 [cytosol] (R-HSA-163531)	0.556	3
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3

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