Reactome | HSPE1 [mitochondrial matrix]

HSPE1 [mitochondrial matrix]

Stable Identifier

R-HSA-9857069

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

10 kDa heat shock protein, mitochondrial, CH10_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8WWX9 SELM

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External Reference Information

External Reference

UniProt:P61604 HSPE1

Gene Names

HSPE1

Chain

initiator methionine:1, chain:2-102

Reference Genes

BioGPS Gene:3336 HSPE1

COSMIC (genes):HSPE1 HSPE1

CTD Gene:3336 HSPE1

dbSNP Gene:3336 HSPE1

ENSEMBL:ENSG00000115541 HSPE1

HGNC:5269 HSPE1

KEGG:hsa:3336 HSPE1

Monarch:3336 HSPE1

NCBI Gene:3336 HSPE1

OMIM:600141 HSPE1

UCSC:P61604 HSPE1

Reference Transcript

RefSeq:NM_002157.3 HSPE1

Other Identifiers

11716350_a_at

11716351_s_at

11753996_x_at

205133_PM_s_at

205133_s_at

2521480

2521481

2521482

2521483

2521484

2521485

2521486

2521487

2521488

2521489

2521490

2521491

2521492

2521493

2521494

2521495

2521496

2599940

3336

3608284

39353_at

72987_f_at

7895692

8047223

A_23_P56922

A_33_P3325306

GE79023

GO:0001649

GO:0003723

GO:0005515

GO:0005524

GO:0005739

GO:0005759

GO:0006457

GO:0006986

GO:0016020

GO:0030154

GO:0044183

GO:0046872

GO:0051082

GO:0051087

GO:0070062

GO:0097193

HMNXSV003010569

HMNXSV003050387

HMNXSV003052538

ILMN_1803775

ILMN_2092536

TC02005004.hg

U07550_at

g4504522_3p_a_at

Participates

as an output of

ATF5 and HSF1 trimer activate expression of HSPE1 (Homo sapiens)

Other forms of this molecule

HSPE1 [cytosol]

Cross References

RefSeq

NP_002148.1

ENSEMBL

ENST00000233893, ENSP00000233893, ENSG00000115541

OpenTargets

ENSG00000115541

GeneCards

HSPE1

HPA

ENSG00000115541-HSPE1

PRO

P61604

Pharos - Targets

P61604

GlyGen

P61604

PDB

6HT7, 6MRC, 6MRD, 8G7N, 8G7O, 4PJ1

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.615	17
UniProt:Q8WWX9 SELM			0.556	3
UniProt:Q96HA8 NTAQ1			0.556	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4

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