Reactome | GID8 [cytosol]

GID8 [cytosol]

Stable Identifier

R-HSA-9861665

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

TWA1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NWU2 GID8

Gene Names

GID8, C20orf11, TWA1

Chain

chain:1-228

Reference Genes

BioGPS Gene:54994 GID8

COSMIC (genes):GID8 GID8

CTD Gene:54994 GID8

dbSNP Gene:54994 GID8

ENSEMBL:ENSG00000101193 GID8

HGNC:15857 GID8

KEGG:hsa:54994 GID8

Monarch:54994 GID8

NCBI Gene:54994 GID8

OMIM:611625 GID8

UCSC:Q9NWU2 GID8

Reference Transcript

Other Identifiers

11717042_at

11717043_at

11748227_a_at

16915804

218448_PM_at

218448_at

225376_PM_at

225376_at

243676_PM_at

243676_at

3893073

3893075

3893076

3893078

3893080

3893082

3893083

3893084

3893085

3893087

53723_at

54994

57736_at

73843_at

8064007

A_14_P125641

A_23_P56971

A_24_P219971

GE55569

GO:0000151

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0008284

GO:0016055

GO:0030054

GO:0030163

GO:0042803

GO:0043161

GO:0043226

GO:0090263

HMNXSV003004012

Hs.12245.0.S1_3p_at

Hs.125060.0.A1_3p_at

ILMN_1755909

PH_hs_0005754

RNA95027|RNS_109_195

TC20000501.hg

g8923556_3p_at

Participates

as a component of

Muskelin:GID8:RANBP9:WDR26 [cytosol] (Homo sapiens)

Inferred To

Q54X16 [cytosol] (Dictyostelium discoideum)

Ghost homologue of GID8 [cytosol] (Xenopus tropicalis)

Hou [cytosol] (Drosophila melanogaster)

Gid8 [cytosol] (Mus musculus)

Gid8 [cytosol] (Rattus norvegicus)

gid8b [cytosol] (Danio rerio)

gid8a [cytosol] (Danio rerio)

GID8 [cytosol] (Bos taurus)

GID8 [cytosol] (Canis familiaris)

GID8 [cytosol] (Gallus gallus)

GID8 [cytosol] (Saccharomyces cerevisiae)

GID8 [cytosol] (Sus scrofa)

gid8 [cytosol] (Schizosaccharomyces pombe)

Homologues of GID8 [cytosol] (Danio rerio)

Cross References

RefSeq

NP_060366.1, XP_047296202.1, XP_054179560.1, XP_047296203.1

ENSEMBL

ENSP00000266069, ENST00000266069, ENSG00000101193

OpenTargets

ENSG00000101193

GeneCards

GID8

HPA

ENSG00000101193-GID8

PRO

Q9NWU2

Pharos - Targets

Q9NWU2

PDB

7NSC

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96S59 RANBP9	1	RANBP9 [cytosol] (R-HSA-374586)	0.789	7
UniProt:Q6VN20 RANBP10	1	RANBP10 [cytosol] (R-HSA-8851865)	0.725	5
UniProt:P13385 TDGF1	1	N-aspartyl-glycosylphosphatidylinositolethanolamine-TDGF1(31-188) [plasma membrane] (R-HSA-452300)	0.643	4
UniProt:P43034 PAFAH1B1	1	PAFAH1B1 [cytosol] (R-HSA-376249)	0.638	3
UniProt:O15173 PGRMC2	4	PGRMC2 [nuclear envelope] (R-HSA-9707674) PGRMC2 [nucleoplasm] (R-HSA-9707859) PGRMC2 [endoplasmic reticulum membrane] (R-HSA-9714349) PGRMC2 [endosome membrane] (R-HSA-9715090)	0.638	3
UniProt:O60313 OPA1	3	OPA1 [mitochondrial inner membrane] (R-HSA-8867508) OPA1(88-194) [mitochondrial inner membrane] (R-HSA-8867509) OPA1(195-960) [mitochondrial inner membrane] (R-HSA-8867513)	0.638	3
UniProt:O43464 HTRA2	1	HTRA2 [mitochondrial intermembrane space] (R-HSA-56655)	0.615	3
UniProt:P09237 MMP7	6	MMP7(95-267) [extracellular region] (R-HSA-1442479) MMP7(18-267) [extracellular region] (R-HSA-1604734) MMP7(18-94) [extracellular region] (R-HSA-1604729) MMP7(51-267) [extracellular region] (R-HSA-1604766) MMP7(18-50) [extracellular region] (R-HSA-1604759) MMP7(51-94) [extracellular region] (R-HSA-1604760)	0.527	2
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.527	4
UniProt:P17900 GM2A	3	GM2A(32-193) [extracellular region] (R-HSA-6806181) GM2A(32-193) [azurophil granule lumen] (R-HSA-6799160) GM2A(32-193) [lysosomal lumen] (R-HSA-1605614)	0.508	2
UniProt:P07476 IVL	2	IVL [cornified envelope] (R-HSA-8847720) IVL [cytosol] (R-HSA-6810837)	0.508	2

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