Reactome | TTC19 [mitochondrial inner membrane]

TTC19 [mitochondrial inner membrane]

Stable Identifier

R-HSA-9906047

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Locations in the PathwayBrowser for interactor UniProt:Q6ZSJ9 SHSA6

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External Reference Information

External Reference

UniProt:Q6DKK2 TTC19

Gene Names

TTC19

Chain

transit peptide:1-70, chain:71-380

Reference Genes

BioGPS Gene:54902 TTC19

COSMIC (genes):TTC19 TTC19

CTD Gene:54902 TTC19

dbSNP Gene:54902 TTC19

ENSEMBL:ENSG00000011295 TTC19

HGNC:26006 TTC19

KEGG:hsa:54902 TTC19

Monarch:54902 TTC19

NCBI Gene:54902 TTC19

OMIM:613814 TTC19

UCSC:Q6DKK2 TTC19

Reference Transcript

Other Identifiers

11716645_a_at

11756376_a_at

16831388

217964_PM_at

217964_at

3599866

3711900

3711901

3711902

3711903

3711904

3711906

3711907

3711908

3711909

3711911

3711919

3711920

3711921

3711922

3711924

3711925

3711926

3711927

3711928

3711929

3711930

3711931

3711932

3711933

3711934

3711942

3711943

3711944

3711945

3711946

3711947

3711948

4020644

44740_at

51100_at

54902

8005141

A_14_P104275

A_23_P50008

A_24_P126393

A_33_P3230738

GE583915

GE788201

GE82224

GO:0000281

GO:0000910

GO:0005515

GO:0005739

GO:0005743

GO:0005813

GO:0005815

GO:0030496

GO:0034551

GO:0043226

GO:0051301

GO:0065003

HMNXSV003031621

HMNXSV003052621

ILMN_2192385

PH_hs_0031982

TC17000181.hg

TC17002076.hg

g8923319_3p_at

This entity regulates

Positively

TTC19 clears UQCRFS1 fragments from Complex III (Homo sapiens)

Inferred To

TTC19 [mitochondrial inner membrane] (Bos taurus)

TTC19 [mitochondrial inner membrane] (Gallus gallus)

TTC19 [mitochondrial inner membrane] (Sus scrofa)

Ttc19 [mitochondrial inner membrane] (Drosophila melanogaster)

Ttc19 [mitochondrial inner membrane] (Mus musculus)

Ttc19 [mitochondrial inner membrane] (Rattus norvegicus)

ddl-3 [mitochondrial inner membrane] (Caenorhabditis elegans)

ttc19 [mitochondrial inner membrane] (Danio rerio)

Cross References

OpenTargets

ENSG00000011295

ENSEMBL

ENST00000261647, ENSP00000261647

HPA

ENSG00000011295-TTC19

PRO

Q6DKK2

Pharos - Targets

Q6DKK2

Interactors (52)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95872 GPAN1			0.742	6
UniProt:Q8IYA8 IHO1			0.718	6
UniProt:P54253 ATX1			0.666	7
UniProt:O15273 TCAP	1	TCAP [cytosol] (R-HSA-390571)	0.666	4
UniProt:O43464 HTRA2	1	HTRA2 [mitochondrial intermembrane space] (R-HSA-56655)	0.659	4
UniProt:Q16774 GUK1	1	GUK1 [cytosol] (R-HSA-58048)	0.589	2
UniProt:P30085 CMPK1	1	CMPK1 [cytosol] (R-HSA-73493)	0.564	2
UniProt:Q6ZSJ9 SHSA6			0.556	3
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.556	3
UniProt:P09455 RBP1	1	RBP1 [cytosol] (R-HSA-74841)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P12872 MLN	1	MLN(26-47) [extracellular region] (R-HSA-444169)	0.556	3
UniProt:P07954 FH	1	FH [mitochondrial matrix] (R-HSA-70980)	0.556	3
IntAct:EBI-10171584 80125			0.556	3
UniProt:Q13207 TBX2	1	TBX2 [nucleoplasm] (R-HSA-9825814)	0.556	3
UniProt:Q9BRK3 MXRA8	2	p-MXRA8 [endoplasmic reticulum lumen] (R-HSA-8957010) MXRA8 [endoplasmic reticulum lumen] (R-HSA-8956693)	0.556	3
UniProt:Q9H788 SH24A			0.556	3
UniProt:O00746 NME4	1	NME4 [mitochondrial inner membrane] (R-HSA-60026)	0.556	3
UniProt:Q9C0B1-2 Q9C0B12			0.556	3
UniProt:Q9NTX9 F217B			0.556	3
UniProt:Q5JTJ3 COA6	2	4xHC-COA6 [mitochondrial intermembrane space] (R-HSA-8874958) COA6 [mitochondrial intermembrane space] (R-HSA-8874929)	0.556	3
UniProt:Q9H0W8 SMG9	1	SMG9 [cytosol] (R-HSA-927812)	0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:P07741 APRT	6	APRT [secretory granule lumen] (R-HSA-6801079) APRT [extracellular region] (R-HSA-6806528) APRT [cytosol] (R-HSA-50171) APRT M136T [cytosol] (R-HSA-9734184) APRT L110P [cytosol] (R-HSA-9734191) APRT D65V [cytosol] (R-HSA-9734183)	0.556	3
UniProt:O43679 LDB2			0.556	3
UniProt:Q96C01 F136A			0.556	3
UniProt:P78424 PO6F2			0.556	3
UniProt:Q9Y2K6 USP20	1	USP20 [cytosol] (R-HSA-5696946)	0.556	3
UniProt:Q9BVN2 RUSC1			0.556	3
IntAct:EBI-22432104 CCSB ORF ID			0.556	3
UniProt:Q9H1P6 CMIP1			0.556	3
UniProt:P35452-2 P354522			0.556	3
UniProt:Q96JM7-2 L3MBTL3			0.556	3
UniProt:Q9NRA8 4ET			0.556	3
UniProt:P21549 AGXT	2	AGXT [cytosol] (R-HSA-9033128) PXLP-AGXT [peroxisomal matrix] (R-HSA-389669)	0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q9H8Y8 GORASP2	2	p-T222,T225-GORASP2 [Golgi membrane] (R-HSA-2422965) GORASP2 [Golgi membrane] (R-HSA-2422385)	0.556	5
UniProt:Q96JM7 LMBL3			0.556	3
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:P0CG20 PRR35			0.556	3
UniProt:Q70EL1-9 USP54			0.556	3
UniProt:P0C7X2 ZNF688	1	ZNF688 [nucleoplasm] (R-HSA-2248884)	0.556	3
UniProt:Q8N1D0-2 SLC22A18AS			0.556	5
UniProt:Q04864 REL	2	REL [cytosol] (R-HSA-1168579) REL [nucleoplasm] (R-HSA-1168585)	0.556	3
UniProt:Q07020 RPL18	1	RPL18 [cytosol] (R-HSA-72420)	0.527	3
UniProt:Q6ZR37 PKHG7			0.527	2
UniProt:Q9P270 SLAI2			0.527	2
UniProt:Q02742 GCNT1	1	GCNT1 [Golgi membrane] (R-HSA-914020)	0.527	2
UniProt:Q8TCX5 RHPN1	1	RHPN1 [cytosol] (R-HSA-5667017)	0.527	2
UniProt:Q12950 FOXD4			0.527	2
UniProt:P14324 FDPS	1	FDPS [cytosol] (R-HSA-981566)	0.527	2
UniProt:P02100 HBE1	1	HBE1 [cytosol] (R-HSA-1008215)	0.499	3

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