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ZFC3H1 [nucleoplasm]
Stable Identifier
R-HSA-9930046
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Zinc finger C3H1 domain-containing protein, ZC3H1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Nuclear RNA decay (Homo sapiens)
MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome (Homo sapiens)
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
PAXT connection [nucleoplasm] (Homo sapiens)
ZFC3H1 [nucleoplasm] (Homo sapiens)
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PAPBN1:RNA exosome [nucleoplasm] (Homo sapiens)
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
PAXT connection [nucleoplasm] (Homo sapiens)
ZFC3H1 [nucleoplasm] (Homo sapiens)
RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA (Homo sapiens)
PAXT connection [nucleoplasm] (Homo sapiens)
ZFC3H1 [nucleoplasm] (Homo sapiens)
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PAPBN1:RNA exosome [nucleoplasm] (Homo sapiens)
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
PAXT connection [nucleoplasm] (Homo sapiens)
ZFC3H1 [nucleoplasm] (Homo sapiens)
The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 (Homo sapiens)
CBCA:ZFC3H1:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
ZFC3H1 [nucleoplasm] (Homo sapiens)
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
PAXT connection [nucleoplasm] (Homo sapiens)
ZFC3H1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60293 ZFC3H1
Gene Names
ZFC3H1, CCDC131, KIAA0546, PSRC2
Chain
initiator methionine:, chain:2-1989
Reference Genes
BioGPS Gene:196441 ZFC3H1
COSMIC (genes):ZFC3H1 ZFC3H1
CTD Gene:196441 ZFC3H1
dbSNP Gene:196441 ZFC3H1
ENSEMBL:ENSG00000133858 ZFC3H1
HGNC:28328 ZFC3H1
KEGG:hsa:196441 ZFC3H1
Monarch:196441 ZFC3H1
NCBI Gene:196441 ZFC3H1
OMIM:620956 ZFC3H1
UCSC:O60293 ZFC3H1
Reference Transcript
RefSeq:NM_144982.4 ZFC3H1
Other Identifiers
11743317_at
11743318_s_at
11762631_a_at
11762632_at
1553736_PM_at
1553736_at
16767540
196441
213065_PM_at
213065_at
3462101
3462102
3462103
3462104
3462105
3462106
3462107
3462108
3462109
3462110
3462111
3462112
3462113
3462114
3462115
3462116
3462117
3462119
3462120
3462121
3462122
3462123
3462124
3462125
3462126
3462127
3462129
3462130
3462131
3462134
3462135
3462136
3462137
3462138
3462139
3462140
3462142
3462143
3462144
3462145
3462146
3462147
3462149
3462150
3462151
3462152
3462153
3462154
3462155
3462156
3462158
3462161
3462163
3462164
3462165
3462166
3462169
3462170
3462171
3462172
3462173
3462177
3462180
3462181
3462182
3462183
3462184
3462185
3462186
3462187
3462188
35184_at
49897_at
74454_at
7964937
A_23_P150950
A_23_P332908
GE53270
GO:0000178
GO:0005515
GO:0005615
GO:0005634
GO:0006396
GO:0043226
GO:0046872
HMNXSV003035991
Hs.26764.0.S1_3p_at
Hs2.245383.1.S1_3p_at
ILMN_1803590
PH_hs_0025377
TC12001726.hg
Participates
as a component of
PAXT connection [nucleoplasm] (Homo sapiens)
CBCA:ZFC3H1:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
Inferred To
zfc3h1 [nucleoplasm]
(Xenopus tropicalis)
ZFC3H1 [nucleoplasm]
(Bos taurus)
ZFC3H1 [nucleoplasm]
(Canis familiaris)
ZFC3H1 [nucleoplasm]
(Gallus gallus)
ZFC3H1 [nucleoplasm]
(Sus scrofa)
Zfc3h1 [nucleoplasm]
(Mus musculus)
Zfc3h1 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of ZFC3H1 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of ZFC3H1 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of ZFC3H1 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of ZFC3H1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
ENSEMBL
ENST00000548100
,
ENSP00000368017
,
ENST00000552994
,
ENSG00000133858
,
ENST00000378743
,
ENSP00000446995
,
ENSP00000450044
OpenTargets
ENSG00000133858
GeneCards
ZFC3H1
HPA
ENSG00000133858-ZFC3H1
PRO
O60293
Pharos - Targets
O60293
GlyGen
O60293
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.667
3
UniProt:Q9NRG4 SMYD2
1
SMYD2 [nucleoplasm]
(R-HSA-3222233)
0.527
2
UniProt:Q15813 TBCE
1
TBCE [cytosol]
(R-HSA-379539)
0.527
2
UniProt:Q14493 SLBP
2
SLBP [nucleoplasm]
(R-HSA-64547)
SLBP [cytosol]
(R-HSA-141613)
0.527
2
UniProt:Q9BWT3 PAPOLG
1
PAPOLG [nucleoplasm]
(R-HSA-9934098)
0.527
2
UniProt:Q9UMX1 SUFU
3
SUFU [ciliary base]
(R-HSA-5610424)
SUFU [cytosol]
(R-HSA-445455)
SUFU [ciliary tip]
(R-HSA-5610426)
0.527
3
UniProt:Q96LA8 PRMT6
1
PRMT6 [nucleoplasm]
(R-HSA-5226884)
0.527
2
UniProt:P67775 PPP2CA
4
PPP2CA [cytosol]
(R-HSA-165971)
PPP2CA [nucleoplasm]
(R-HSA-165978)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
0.527
2
UniProt:Q9NQT4 EXOSC5
3
EXOSC5 [cytosol]
(R-HSA-429889)
EXOSC5 [nucleoplasm]
(R-HSA-6791550)
EXOSC5 [nucleolus]
(R-HSA-9935829)
0.527
2
UniProt:Q86TI0 TBC1D1
2
TBC1D1 [cytoplasmic vesicle membrane]
(R-HSA-1454718)
p-S237-TBC1D1 [cytosol]
(R-HSA-1454673)
0.527
2
UniProt:Q13901 C1D
2
C1D [nucleoplasm]
(R-HSA-6791515)
C1D [nucleolus]
(R-HSA-9935822)
0.527
2
UniProt:Q8N4J0 CARNMT1
1
CARNMT1 [cytosol]
(R-HSA-8876689)
0.527
3
UniProt:Q92889 ERCC4
1
ERCC4 [nucleoplasm]
(R-HSA-67445)
0.527
2
UniProt:Q86VM9 ZC3H18
1
ZC3H18 [nucleoplasm]
(R-HSA-9930040)
0.527
2
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