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ZC3H3 [nucleoplasm]
Stable Identifier
R-HSA-9933572
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Zinc finger CCCH domain-containing protein 3, ZC3H3_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9NW13 RBM28
Expand all
Metabolism of RNA (Homo sapiens)
Nuclear RNA decay (Homo sapiens)
RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA (Homo sapiens)
ZC3H3 [nucleoplasm] (Homo sapiens)
The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 (Homo sapiens)
ZC3H3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IXZ2 ZC3H3
Gene Names
ZC3H3, KIAA0150, SMICL, ZC3HDC3
Chain
chain:1-948
Reference Genes
BioGPS Gene:23144 ZC3H3
COSMIC (genes):ZC3H3 ZC3H3
CTD Gene:23144 ZC3H3
dbSNP Gene:23144 ZC3H3
ENSEMBL:ENSG00000014164 ZC3H3
HGNC:28972 ZC3H3
KEGG:hsa:23144 ZC3H3
Monarch:23144 ZC3H3
NCBI Gene:23144 ZC3H3
OMIM:618640 ZC3H3
UCSC:Q8IXZ2 ZC3H3
Reference Transcript
RefSeq:NM_015117.2 ZC3H3
Other Identifiers
11726850_a_at
11726851_x_at
17082088
213445_PM_at
213445_at
23144
241056_PM_at
241056_at
3157461
3157462
3157463
3157468
3157469
3157470
3157474
3157477
3157479
3157480
3157483
3157488
3157492
3157508
3157509
3157510
3157511
3157512
3157513
3157514
41078_at
72821_at
8153411
A_23_P9036
A_33_P3423820
D63484_at
GE79230
GO:0003674
GO:0003677
GO:0005634
GO:0005847
GO:0016071
GO:0031124
GO:0032927
GO:0043226
GO:0046332
GO:0046872
GO:0051028
GO:0070412
HMNXSV003008956
HMNXSV003044997
Hs.232207.0.A1_3p_at
Hs.98508.0.S1_3p_at
ILMN_1702389
PH_hs_0024149
TC08001717.hg
Participates
as an output of
RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA (Homo sapiens)
as a component of
PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] (Homo sapiens)
as an input of
The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 (Homo sapiens)
Inferred To
ZC3H3 [nucleoplasm]
(Bos taurus)
ZC3H3 [nucleoplasm]
(Canis familiaris)
ZC3H3 [nucleoplasm]
(Gallus gallus)
ZC3H3 [nucleoplasm]
(Sus scrofa)
Ghost homologue of ZC3H3 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of ZC3H3 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of ZC3H3 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of ZC3H3 [nucleoplasm]
(Schizosaccharomyces pombe)
zc3h3 [nucleoplasm]
(Xenopus tropicalis)
Zc3h3 [nucleoplasm]
(Mus musculus)
Zc3h3 [nucleoplasm]
(Rattus norvegicus)
Cross References
OpenTargets
ENSG00000014164
ENSEMBL
ENSG00000014164
,
ENSP00000262577
,
ENST00000262577
GeneCards
ZC3H3
HPA
ENSG00000014164-ZC3H3
PRO
Q8IXZ2
Pharos - Targets
Q8IXZ2
GlyGen
Q8IXZ2
Interactors (40)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P36941 LTBR
1
LTBR [plasma membrane]
(R-HSA-5668750)
0.527
2
UniProt:Q9NW13 RBM28
1
RBM28 [nucleoplasm]
(R-HSA-6791192)
0.527
2
UniProt:Q9H7B2 RPF2
0.527
3
UniProt:Q8N567 ZCHC9
0.527
2
UniProt:Q9HAN9 NMNAT1
1
NMNAT1 [nucleoplasm]
(R-HSA-200484)
0.527
2
UniProt:O43865 AHCYL1
1
AHCYL1 [endoplasmic reticulum membrane]
(R-HSA-5215973)
0.527
3
UniProt:Q8N9M5 TM102
0.527
2
UniProt:P51398 DAP3
1
DAP3 [mitochondrial inner membrane]
(R-HSA-5368174)
0.527
3
UniProt:Q13823 NOG2
0.527
2
UniProt:Q8TDN6 BRX1
0.527
2
UniProt:O75127 PTCD1
0.527
3
UniProt:Q02539 H1-1
1
HIST1H1A [nucleoplasm]
(R-HSA-211245)
0.527
2
UniProt:Q9H361 PABP3
0.527
2
UniProt:P82664 MRPS10
2
MRPS10 [mitochondrial inner membrane]
(R-HSA-5368190)
MRPS10 [mitochondrial matrix]
(R-HSA-9839687)
0.527
3
UniProt:Q15397 PUM3
0.527
2
UniProt:P62910 RPL32
1
RPL32 [cytosol]
(R-HSA-72456)
0.527
2
UniProt:Q6PKG0 LARP1
1
LARP1 [cytosol]
(R-HSA-9760421)
0.527
2
UniProt:Q9BZE4 GTPB4
0.527
2
UniProt:Q9H9Y2 RPF1
0.527
3
UniProt:O60232 ZNRD2
0.527
2
UniProt:Q9BYD1 MRPL13
1
MRPL13 [mitochondrial inner membrane]
(R-HSA-5368244)
0.527
2
UniProt:P62906 RPL10A
1
RPL10A [cytosol]
(R-HSA-72404)
0.527
2
UniProt:P82933 MRPS9
1
MRPS9 [mitochondrial inner membrane]
(R-HSA-5368194)
0.527
3
UniProt:P49406 MRPL19
1
MRPL19 [mitochondrial inner membrane]
(R-HSA-5368215)
0.527
2
UniProt:O14595 CTDSP2
1
CTDSP2 [nucleoplasm]
(R-HSA-535488)
0.527
2
UniProt:O95900 TRUB2
0.527
3
UniProt:Q9H5V7 IKZF5
0.527
3
UniProt:Q96EH3 MASU1
0.527
2
UniProt:Q9Y4C8 RBM19
0.527
3
UniProt:Q9HCE1 MOV10
1
MOV10 [cytosol]
(R-HSA-427772)
0.527
2
UniProt:P42696 RBM34
0.527
2
UniProt:O60832 DKC1
1
DKC1 [nucleoplasm]
(R-HSA-163102)
0.527
2
UniProt:Q9UF02 CCG5
0.527
2
UniProt:P82675 MRPS5
1
MRPS5 [mitochondrial inner membrane]
(R-HSA-5368176)
0.527
3
UniProt:Q9UC06 ZNF70
1
ZNF70 [nucleoplasm]
(R-HSA-2454140)
0.527
2
UniProt:Q9Y2Z4 YARS2
1
YARS2 [mitochondrial matrix]
(R-HSA-379634)
0.527
3
UniProt:Q9NPE2 NGRN
0.527
3
UniProt:P16403 H1-2
1
HIST1H1C [nucleoplasm]
(R-HSA-211237)
0.527
2
UniProt:Q9Y291 MRPS33
1
MRPS33 [mitochondrial inner membrane]
(R-HSA-5368228)
0.527
3
UniProt:Q8IUE6 H2AC21
11
AcK-HIST2H2AB [nucleoplasm]
(R-HSA-4551335)
HIST2H2AB [nucleoplasm]
(R-HSA-4549212)
MeR12-HIST2H2AB [nucleoplasm]
(R-HSA-5229207)
Me2aR12-HIST2H2AB [nucleoplasm]
(R-HSA-5229314)
MeR4-HIST2H2AB [nucleoplasm]
(R-HSA-5244632)
Me2aR4-HIST2H2AB [nucleoplasm]
(R-HSA-5244588)
MeR30-HIST2H2AB [nucleoplasm]
(R-HSA-5244540)
Me2aR30-HIST2H2AB [nucleoplasm]
(R-HSA-5244567)
AcK6-HIST2H2AB [nucleoplasm]
(R-HSA-4568609)
Ub-HIST2H2AB [nucleoplasm]
(R-HSA-6782490)
K63polyUb-HIST2H2AB [nucleoplasm]
(R-HSA-6783295)
0.527
2
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