IRF2 binds the promoters of Interferon alpha and beta

Stable Identifier
R-HSA-994038
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
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IRF2 binds the promoters of Interferon alpha and beta
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Interferon regulatory factor 2 (IRF-2) represses the action of IRF-1 on type I interferon genes (Harada et al, 1989, 1990; Palombella & Maniatis, 1992) by competing with IRF-1 for binding at the PRDI site.

Literature References
PubMed ID Title Journal Year
1630448 Inducible processing of interferon regulatory factor-2

Palombella, VJ, Maniatis, T

Mol Cell Biol 1992
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Authored
Akkerman, JW  (2010-10-29)
Reviewed
Ouwehand, WH  (2010-11-12)
Created
Jupe, S  (2010-11-05)
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