Reactome | HMG20B [nucleoplasm]

HMG20B [nucleoplasm]

Stable Identifier

R-HSA-996745

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, HM20B_HUMAN, HMG box-containing protein 20B

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - Potential therapeutics for SARS (Homo sapiens)
        
        HDAC1:2-containing complex binds HDAC2 Inhibitors (Homo sapiens)
        
        HDAC1:2-containing complex [nucleoplasm] (Homo sapiens)
        
        BHC complex [nucleoplasm] (Homo sapiens)
        
        HMG20B [nucleoplasm] (Homo sapiens)
        
        HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Homo sapiens)
        
        HDAC1:2-containing complex [nucleoplasm] (Homo sapiens)
        
        BHC complex [nucleoplasm] (Homo sapiens)
        
        HMG20B [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9P0W2 HMG20B

Gene Names

HMG20B, BRAF35, HMGX2, HMGXB2, SMARCE1R

Chain

chain:1-317

Reference Genes

BioGPS Gene:10362 HMG20B

COSMIC (genes):HMG20B HMG20B

CTD Gene:10362 HMG20B

dbSNP Gene:10362 HMG20B

ENSEMBL:ENSG00000064961 HMG20B

HGNC:5002 HMG20B

Monarch:10362 HMG20B

NCBI Gene:10362 HMG20B

OMIM:605535 HMG20B

UCSC:Q9P0W2 HMG20B

Reference Transcript

RefSeq:NM_006339.2 HMG20B

Other Identifiers

10362

11715826_x_at

11744661_a_at

11744662_x_at

16856980

209113_3p_s_at

209113_PM_s_at

209113_s_at

210719_PM_s_at

210719_s_at

3817041

3817042

3817043

3817044

3817045

3817046

3817047

3817048

3817049

3817050

3817051

3817052

3817053

3817054

3817055

3817056

3817057

3817058

3817059

3817060

3817061

3817062

3817063

3817064

3817065

3817066

3817067

3817068

3817069

41526_at

8024660

A_14_P125287

A_23_P119543

A_33_P3359268

A_33_P3394599

A_33_P3394605

GE54682

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0010468

GO:0016604

GO:0016925

GO:0030154

GO:0033234

GO:0035914

GO:0043226

GO:0045666

HMNXSV003003325

ILMN_1651315

TC19000072.hg

g12803454_3p_a_at

g9858862_3p_a_at

g9858862_3p_s_at

Participates

as a component of

BHC complex [nucleoplasm] (Homo sapiens)

Inferred To

HMG20B [nucleoplasm] (Bos taurus)

HMG20B [nucleoplasm] (Canis familiaris)

HMG20B [nucleoplasm] (Gallus gallus)

HMG20B [nucleoplasm] (Sus scrofa)

Hmg20b [nucleoplasm] (Mus musculus)

Hmg20b [nucleoplasm] (Rattus norvegicus)

hmg20b [nucleoplasm] (Xenopus tropicalis)

Hmg-2 [nucleoplasm] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000333651, ENSP00000328269

OpenTargets

ENSG00000064961

HPA

ENSG00000064961-HMG20B

PRO

Q9P0W2

Pharos - Targets

Q9P0W2

GlyGen

Q9P0W2

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.788	7
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.725	5
UniProt:P51587 BRCA2	20	BRCA2 D2983Ffs34 [cytosol] (R-HSA-9709538) BRCA2 K2555 [cytosol] (R-HSA-9711337) BRCA2 N2553Tfs95 [cytosol] (R-HSA-9712872) BRCA2 T2685Hfs9 [cytosol] (R-HSA-9712879) BRCA2 K2674Rfs2 [cytosol] (R-HSA-9712610) BRCA2 S3231 [cytosol] (R-HSA-9711458) BRCA2 I2675Dfs6 [cytosol] (R-HSA-9712869) BRCA2 R2625 [cytosol] (R-HSA-9711482) BRCA2 E3071* [cytosol] (R-HSA-9711354) BRCA2 V2716Wfs17 [cytosol] (R-HSA-9712761) BRCA2 W2586 [cytosol] (R-HSA-9711487) BRCA2 P2767Lfs10 [cytosol] (R-HSA-9712509) BRCA2 K3032 [cytosol] (R-HSA-9711485) BRCA2 S2835* [cytosol] (R-HSA-9711345) BRCA2 Y3006* [cytosol] (R-HSA-9711222) BRCA2 L2926* [cytosol] (R-HSA-9711348) BRCA2 R3128* [cytosol] (R-HSA-9711177) BRCA2 E2599* [cytosol] (R-HSA-9711304) BRCA2 E2571* [cytosol] (R-HSA-9711560) BRCA2 Y2977* [cytosol] (R-HSA-9711182)	0.576	8
UniProt:O75928-2 PIAS2	1	PIAS2-2 [nucleoplasm] (R-HSA-2993779)	0.556	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q8N0S2 SYCE1	1	SYCE1 [nucleoplasm] (R-HSA-912456)	0.556	3
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.527	3