Dephosphorylation of JAK1 by SHP1

Stable Identifier
R-HSA-997314
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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General
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SHP1 directly associates with and dephosphorylates JAK1/2.

Literature References
PubMed ID Title Journal Year
8943354 Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

Jiao, H, Berrada, K, Yang, W, Tabrizi, M, Platanias, LC, Yi, T

Mol Cell Biol 1996
18508557 Protein tyrosine phosphatases in the JAK/STAT pathway

Xu, D, Qu, CK

Front Biosci 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine phosphatase activity of PTPN6 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created