Reactome: A Curated Pathway Database

TDPK phosphorylates ThDP to ThTP

Stable Identifier
R-HSA-997381
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
ThDP + ATP <-> ThTP + ADP
Locations in the PathwayBrowser
Summation

Thiamin triphosphate (ThTP) is believed to be synthesized from thiamin diphosphate (ThDP), catalyzed by ThDP kinase (TDPK), an enzyme that remains poorly characterized (Nishino et al, 1983).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
thiamine-diphosphate kinase activity of TDPK [cytosol] TDPK [cytosol] thiamine-diphosphate kinase activity (0050331)
Cross References
Rhea