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Go!
GSDMD pore complex
Categories
Protein
Curator
Veronica Shamovsky
Designer
Cristoffer Sevilla
Description
GSDMD-N forms large transmembrane pores composed of 31 to 34 subunits that allow the release of interleukin-1 family cytokines and drive pyroptosis
Icon preview
SVG
PNG
EMF
Locations in the PathwayBrowser
Expand all
Disease (R-HSA-1643685)
Diseases of programmed cell death (R-HSA-9645723)
Programmed Cell Death (R-HSA-5357801)
Regulated Necrosis (R-HSA-5218859)
Entries for GSDMD pore complex
dithiocarb-C191-GSDMD(1-275) [cytosol]
GSDMD [cytosol]
GSDMD [extracellular region]
GSDMD [ficolin-1-rich granule lumen]
GSDMD [specific granule lumen]
GSDMD [tertiary granule lumen]
GSDMD(1-268) [cytosol]
GSDMD(1-275) [cytosol]
GSDMD(1-87) [cytosol]
GSDMD(269-484) [cytosol]
GSDMD(276-484) [cytosol]
GSDMD(88-484) [cytosol]
S-(2-succinyl)-C191-GSDMD [cytosol]
External References
UNIPROT
P57764
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