Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Dock8 [cytosol]
Stable Identifier
R-MMU-1011619
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
DOCK8, Q8C147
Locations in the PathwayBrowser
Expand all
Hemostasis (Mus musculus)
Factors involved in megakaryocyte development and platelet production (Mus musculus)
DOCKs bind to RhoGEFs (Mus musculus)
DOCK-GEFs [cytosol] (Mus musculus)
Dock8 [cytosol] (Mus musculus)
DOCK-GEFs:RAC1, CDC42 [cytosol] (Mus musculus)
DOCK-GEFs [cytosol] (Mus musculus)
Dock8 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
CDC42 GTPase cycle (Mus musculus)
CDC42 GEFs activate CDC42 (Mus musculus)
CDC42 GEFs [cytosol] (Mus musculus)
Dock8 [cytosol] (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 GEFs activate RAC1 (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
Dock8 [cytosol] (Mus musculus)
RHOJ GTPase cycle (Mus musculus)
RHOJ GEFs activate RHOJ (Mus musculus)
RHOJ GEFs [cytosol] (Mus musculus)
Dock8 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8C147
Gene Names
Dock8
Reference Genes
BioGPS Gene:76088 Dock8
ENSEMBL:ENSMUSG00000052085
ENSEMBL:ENSMUSG00000052085.8 Dock8
KEGG Gene (Mus musculus):76088 Dock8
Monarch:76088 Dock8
NCBI Gene:76088 Dock8
UCSC:Q8C147 Dock8
Reference Transcript
RefSeq:NM_028785.3 Dock8
Other Identifiers
10462140
116711_at
1431961_at
1433437_at
1449419_at
17358274
4309889
4370849
4373374
4390849
4396461
4463058
4476111
4547187
4561293
4582501
4613810
4615650
4621154
4639178
4648242
4658060
4667829
4680655
4703818
4704345
4738759
4755732
4781173
4797148
4810115
4851747
4863171
4874019
4875579
4879132
4894511
4938030
4949977
5012911
5030156
5044174
5059167
5077077
5078526
5183756
5204416
5220248
5225026
5247013
5340076
5359219
5360678
5361191
5379539
5406573
5410674
5435383
5441300
5447655
5460816
5478004
5514464
5515869
5552189
76088
A_51_P483511
A_52_P321342
A_52_P608156
A_55_P2728718
GE41416
GO:0001771
GO:0002376
GO:0005085
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0007155
GO:0007163
GO:0007264
GO:0012501
GO:0016020
GO:0023052
GO:0031252
GO:0031256
GO:0031258
GO:0036336
GO:0042995
GO:0048870
GO:0061485
GO:0070233
GO:0098772
GO:1903905
GO:1990869
GO:2000406
ILMN_1223407
ILMN_2655163
mMC019559
mMC022076
Participates
as a candidate of
CDC42 GEFs [cytosol] (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
DOCK-GEFs [cytosol] (Mus musculus)
as a member of
RHOJ GEFs [cytosol] (Mus musculus)
Inferred From
DOCK8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_083061.2
Ensembl
ENSMUSP00000025831
,
ENSMUSG00000052085
,
ENSMUST00000025831
PRO
Q8C147
MGI
1921396
PDB
7CLY
,
3VHL
,
7CLX
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text