Cables links Cdk5 and Abl1

Stable Identifier
R-MMU-1013873
Type
Reaction
Species
Mus musculus
Compartment
Summation

In neurons, Cables1 links Cdk5 and c-Abl, enhancing Cdk5 tyrosine-15 phosphorylation which results in increased Cdk5 activity, important in neurite outgrowth (Zukerberg et al. 2000).

Literature References
PubMed ID Title Journal Year
10896159 Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

Zukerberg, LR, Patrick, GN, Nikolic, M, Humbert, S, Wu, CL, Lanier, LM, Gertler, FB, Vidal, M, Van Etten, RA, Tsai, LH

Neuron 2000
Participants
Orthologous Events
Authored
Reviewed