Ptp1b dephosphorylates Jak2

Stable Identifier
R-MMU-1169229
Type
Reaction
Species
Mus musculus
Compartment
General
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Ptp1b dephosphorylates Jak2

Ptp1b dephosphorylates Jak2 (Gu et al. 2003), limiting ligand-dependent signaling.

Literature References
PubMed ID Title Journal Year
12748279 Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling

Gu, F, Dubé, N, Kim, JW, Cheng, A, Ibarra-Sanchez Mde, J, Tremblay, ML, Boisclair, YR

Mol Cell Biol 2003
Participants
Catalyst Activity
Catalyst Activity
Title
protein tyrosine phosphatase activity of Growth hormone:Tyrosine phosphorylated growth hormone receptor-Jak2 dimer:SHP2 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Reviewed
Created
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