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CDC37 [cytosol]
Stable Identifier
R-MMU-1225828
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
MLKL binds HSP90:CDC37 (Mus musculus)
CDC37 [cytosol] (Mus musculus)
MLKL:HSP90:CDC37 [cytosol] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
RIPK3 binds HSP90:CDC37 (Mus musculus)
CDC37 [cytosol] (Mus musculus)
RIPK3:HSP90:CDC37 [cytosol] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ERBB2 (Mus musculus)
Downregulation of ERBB2 signaling (Mus musculus)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Mus musculus)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
CUL5 mediates ubiquitination of ERBB2 (Mus musculus)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
Drug-mediated inhibition of ERBB2 signaling (Mus musculus)
ERBB2 binds TKIs (Mus musculus)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Mus musculus)
CDC37 [cytosol] (Mus musculus)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
Trans-autophosphorylation of ERBB2 heterodimers (Mus musculus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
CDC37 [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
Cdc37 [cytosol]
(Mus musculus)
Participates
as a component of
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Mus musculus)
RIPK3:HSP90:CDC37 [cytosol] (Mus musculus)
MLKL:HSP90:CDC37 [cytosol] (Mus musculus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
as an input of
RIPK3 binds HSP90:CDC37 (Mus musculus)
MLKL binds HSP90:CDC37 (Mus musculus)
as an output of
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Mus musculus)
Inferred From
CDC37 [cytosol]
(Homo sapiens)
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