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Epas1 [nucleoplasm]
Stable Identifier
R-MMU-1234151
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
2xHP-EPAS1, P97481
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to hypoxia (Mus musculus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Mus musculus)
Nuclear VBC complex ubiquitinylates HIF-alpha (Mus musculus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Mus musculus)
hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
Epas1 [nucleoplasm] (Mus musculus)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Mus musculus)
ub-hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
Epas1 [nucleoplasm] (Mus musculus)
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Mus musculus)
hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
Epas1 [nucleoplasm] (Mus musculus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Mus musculus)
hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
Epas1 [nucleoplasm] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Mus musculus)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Mus musculus)
ub-hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
Epas1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P97481 Epas1
Gene Names
Epas1, Hif2a
Chain
chain:1-874
Reference Genes
BioGPS Gene:13819 Epas1
ENSEMBL:ENSMUSG00000024140.11 Epas1
KEGG Gene (Mus musculus):13819 Epas1
Monarch:13819 Epas1
NCBI Gene:13819 Epas1
UCSC:P97481 Epas1
Reference Transcript
RefSeq:NM_010137.3 Epas1
Other Identifiers
102698_at
10447317
114665_at
13819
1435436_at
1449888_at
17340197
4316564
4370736
4425361
4436787
4447694
4482454
4512494
4529798
4566742
4585294
4707847
4725007
4863129
4986702
5002820
5021727
5029958
5087143
5119538
5304859
5409523
5475264
5494098
5555405
5591003
5601440
A_51_P250058
A_51_P307954
A_55_P2053988
A_55_P2077448
GE35356
GO:0000122
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001223
GO:0001228
GO:0001525
GO:0001666
GO:0001892
GO:0001974
GO:0002027
GO:0002070
GO:0002376
GO:0003013
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006979
GO:0007005
GO:0007601
GO:0010467
GO:0016071
GO:0016607
GO:0030097
GO:0030154
GO:0030218
GO:0030324
GO:0036211
GO:0042415
GO:0042421
GO:0042789
GO:0043129
GO:0043226
GO:0043565
GO:0043619
GO:0045893
GO:0045944
GO:0046982
GO:0046983
GO:0048625
GO:0048856
GO:0050877
GO:0050897
GO:0055065
GO:0060586
GO:0061629
GO:0071456
GO:0120162
GO:0140110
GO:1903181
GO:2000434
ILMN_2671698
ILMN_3052632
ILMN_3129160
d89787_at
d89787_g_at
mMC016060
Participates
as a member of
hydroxyPro-HIF-alpha [nucleoplasm] (Mus musculus)
Other forms of this molecule
Epas1 [cytosol]
Epas1 [cytosol]
Epas1 [nucleoplasm]
Epas1 [cytosol]
Epas1 [cytosol]
Inferred From
2xHP-EPAS1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
monohydroxylated proline at 405 (in Homo sapiens)
Coordinate
405
PsiMod Name
monohydroxylated proline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline.
Name
monohydroxylated proline at 531 (in Homo sapiens)
Coordinate
531
PsiMod Name
monohydroxylated proline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline.
Cross References
RefSeq
NP_034267.3
Ensembl
ENSMUSG00000024140
,
ENSMUST00000024954
,
ENSMUSP00000024954
PRO
P97481
MGI
109169
PDB
6E3U
,
4ZPH
,
7W80
,
4ZPK
,
6E3T
,
4ZQD
,
4ZP4
,
6E3S
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53762 Arnt
2
Arnt [nucleoplasm]
(R-MMU-9621312)
Arnt [nucleoplasm]
(R-MMU-1234098)
0.645
5
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