Expression of Srebf1

Stable Identifier
R-MMU-1368139
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, Golgi membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Srebf1
The Srebf1 gene is transcribed to yield mRNA and the mRNA is translated to yield protein (Shimomura et al. 1997). Transcription of Srebf1 is positively regulated by Rora and Ep300 (Lau et al. 2008).
Literature References
PubMed ID Title Journal Year
18441015 The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity

Lau, P, Fitzsimmons, RL, Raichur, S, Wang, SC, Lechtken, A, Muscat, GE

J Biol Chem 2008
9062340 Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

Shimomura, I, Shimano, H, Horton, JD, Goldstein, JL, Brown, MS

J Clin Invest 1997
Participants
Input
Output
This event is regulated
Positively by
Regulator
Rora:Ep300:Srebf1 gene [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of SREBF1 (SREBP1) (Homo sapiens)
Authored
May, B  (2011-06-22)
Reviewed
Delaunay, F  (2012-01-28)
Sancar, A  (2025-02-14)
Albrecht, U  (2025-02-18)
Created
May, B  (2011-06-30)
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