Reactome | Bub1b [cytosol]

Bub1b [cytosol]

Stable Identifier

R-MMU-141436

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

BUB1B, Q9Z1S0

Locations in the PathwayBrowser for interactor UniProt:O95071 UBR5

Expand all

Cell Cycle (Mus musculus)

- Cell Cycle Checkpoints (Mus musculus)
  - Mitotic Spindle Checkpoint (Mus musculus)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
        
        Formation of the MCC complex (Mus musculus)
        
        Bub1b [cytosol] (Mus musculus)
- Cell Cycle, Mitotic (Mus musculus)
  - Regulation of mitotic cell cycle (Mus musculus)
    - APC/C-mediated degradation of cell cycle proteins (Mus musculus)
      - Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
        
        Formation of the MCC complex (Mus musculus)
        
        Bub1b [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9Z1S0

Gene Names

Bub1b

Reference Genes

BioGPS Gene:12236 Bub1b

ENSEMBL:ENSMUSG00000040084

ENSEMBL:ENSMUSG00000040084 Bub1b

KEGG Gene (Mus musculus):12236 Bub1b

Monarch:12236 Bub1b

NCBI Gene:12236 Bub1b

UCSC:Q9Z1S0 Bub1b

Reference Transcript

RefSeq:NM_009773.3 Bub1b

Other Identifiers

10474769

109165_at

12236

1416961_at

1447363_s_at

17374569

4370772

4396277

4486931

4494951

4525208

4541935

4597947

4692347

4781801

4781940

4831756

4849563

4981113

5017803

5233164

5257652

5272888

5308631

5375958

5426713

5435397

5466594

5516062

5574589

5576511

5577793

A_51_P490509

GE35128

GO:0000003

GO:0000166

GO:0000278

GO:0000775

GO:0000776

GO:0000940

GO:0003674

GO:0004672

GO:0004674

GO:0004712

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0005737

GO:0005819

GO:0005829

GO:0005856

GO:0006464

GO:0006468

GO:0006915

GO:0007049

GO:0007059

GO:0007091

GO:0007094

GO:0007165

GO:0008150

GO:0008219

GO:0016301

GO:0016310

GO:0016740

GO:0032991

GO:0033597

GO:0043167

GO:0043226

GO:0048471

GO:0051276

GO:0051301

GO:0051444

GO:0051754

GO:0071459

GO:0106310

GO:0140014

ILMN_2774007

ILMN_2985969

mMC012156

Participates

as a component of

as an input of

Formation of the MCC complex (Mus musculus)

Inferred From

BUB1B [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_033903.2

IntEnz

2.7.11.1

Ensembl

ENSMUST00000038341, ENSMUSP00000037126, ENSMUSG00000040084

PRO

Q9Z1S0

MGI

1333889

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95071 UBR5			0.564	2
UniProt:P30260 CDC27	2	CDC27 [cytosol] (R-HSA-174073) CDC27 [nucleoplasm] (R-HSA-174175)	0.564	2
UniProt:Q9H1A4 ANAPC1	2	ANAPC1 [nucleoplasm] (R-HSA-174217) ANAPC1 [cytosol] (R-HSA-174189)	0.564	2
UniProt:Q96DE5 ANAPC16	2	ANAPC16 [cytosol] (R-HSA-6805138) ANAPC16 [nucleoplasm] (R-HSA-6805137)	0.564	2
UniProt:Q8NHZ8 CDC26	2	CDC26 [nucleoplasm] (R-HSA-174216) CDC26 [cytosol] (R-HSA-174052)	0.564	2
UniProt:Q12834 CDC20	3	CDC20 [cytosol] (R-HSA-141412) CDC20 [nucleoplasm] (R-HSA-174112) PolyUb-CDC20 [nucleoplasm] (R-HSA-6783069)	0.564	2