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GRB2:p-SHP2:p-KIT complex [plasma membrane]
Stable Identifier
R-MMU-1433549
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
GRB2 is indirectly recruited to p-KIT through SHP2 (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
Indirect recruitment of GAB2 to p-KIT (Mus musculus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Mus musculus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
Phosphorylation of GAB2 by SFKs (Mus musculus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
Synthesis of PIP3 from PIP2 by PI3K (Mus musculus)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Grb2 [cytosol]
(Mus musculus)
p-SHP2:p-KIT complex [plasma membrane]
(Mus musculus)
Participates
as an input of
Indirect recruitment of GAB2 to p-KIT (Mus musculus)
as an output of
GRB2 is indirectly recruited to p-KIT through SHP2 (Mus musculus)
as a component of
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
Inferred From
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Homo sapiens)
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