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About
What is Reactome ?
News
Team
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Our Logo
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Privacy Notice
Disclaimer
Digital Preservation
Contact us
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14-3-3 beta/alpha [cytosol]
Stable Identifier
R-MMU-1445100
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
14-3-3 protein beta/alpha, Ywhab, 1433B_MOUSE, Ywhab
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G2/M Checkpoints (Mus musculus)
G2/M DNA damage checkpoint (Mus musculus)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Mus musculus)
Association of p-S216-CDC25C with 14-3-3 proteins (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
FOXO-mediated transcription (Mus musculus)
Regulation of localization of FOXO transcription factors (Mus musculus)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Mus musculus)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Mus musculus)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
DDIT4 binds 14-3-3 dimer (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
DDIT4:14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
DDIT4:14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Rap1 signalling (Mus musculus)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Mus musculus)
14-3-3 beta, zeta [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Mus musculus)
14-3-3 beta, zeta [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Rap1 signal termination by Rap1GAPs (Mus musculus)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Mus musculus)
14-3-3 beta, zeta [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Metabolism of RNA (Mus musculus)
Regulation of mRNA stability by proteins that bind AU-rich elements (Mus musculus)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Mus musculus)
p-S54,92,203-BRF1 binds 14-3-3 (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S92,203-BRF1 binds 14-3-3 (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Mus musculus)
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Activation of BH3-only proteins (Mus musculus)
Activation of BAD and translocation to mitochondria (Mus musculus)
Activation of BAD by calcineurin (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Sequestration of BAD protein by 14-3-3 (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
MAP2K and MAPK activation (Mus musculus)
Dissociation of RAS:RAF complex (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Dual mechanism MAPK inhibitors bind MAPKs (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
MAP2Ks and MAPKs bind to the activated RAF complex (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
MAP2Ks phosphorylate MAPKs (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAF phosphorylates MAP2K dimer (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Negative regulation of MAPK pathway (Mus musculus)
PEBP1 binds activated RAF1 (Mus musculus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
PP2A dephosphorylates RAF1 (Mus musculus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
PP5 dephosphorylates RAF1 S338 (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAF activation (Mus musculus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Inactive RAFs bind YWHAB (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
inactive RAFs:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Mus musculus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
inactive RAFs:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
PP2A dephosphorylates KSR1 (Mus musculus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
PP2A dephosphorylates inactive RAFs (Mus musculus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
inactive RAFs:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Phosphorylation of RAF (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Raf dimer inhibitors bind RAF heterodimers (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
'activator' RAF:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
YWHAB dimer dissociates from KSR1:MARK3 (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
YWHAB dimer dissociates from dephosphorylated RAF (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
MTOR signalling (Mus musculus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
mTORC1 phosphorylates AKT1S1 (Mus musculus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
mTORC1-mediated signalling (Mus musculus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Signaling by Hippo (Mus musculus)
YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-YAP1:YWHAB [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by NTRKs (Mus musculus)
Signaling by NTRK1 (TRKA) (Mus musculus)
Signalling to ERKs (Mus musculus)
Prolonged ERK activation events (Mus musculus)
Frs2-mediated activation (Mus musculus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Mus musculus)
BRAF dimer complex [cytosol] (Mus musculus)
B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
BRAF autophosphorylates downstream of RAP1 and NGF (Mus musculus)
BRAF dimer complex [cytosol] (Mus musculus)
B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:B-Raf complex [endosome membrane] (Mus musculus)
BRAF dimer complex [cytosol] (Mus musculus)
B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Dissociation of phosphorylated MAP2Ks and MAPKs (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Mus musculus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases activate PKNs (Mus musculus)
Association of p-S216-CDC25C with 14-3-3 proteins (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Mus musculus)
14-3-3 dimer [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
14-3-3 beta/alpha [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9CQV8 Ywhab
Gene Names
Ywhab
Chain
chain:1-246, initiator methionine:, chain:2-246
Reference Genes
BioGPS Gene:54401 Ywhab
KEGG:mmu:54401 Ywhab
Monarch:54401 Ywhab
NCBI Gene:54401 Ywhab
UCSC:Q9CQV8 Ywhab
Reference Transcript
RefSeq:NM_018753.6 Ywhab
RefSeq:XM_006499909.1 Ywhab
Other Identifiers
10478424
1420878_a_at
1420879_a_at
1420880_a_at
1436783_x_at
1455815_a_at
17379328
4462964
4574238
4924949
4985326
5184820
5257406
5273775
5317836
5342279
5364853
5405430
54401
98053_at
A_52_P112958
A_55_P2933370
GE37307
GO:0003824
GO:0004497
GO:0004860
GO:0005515
GO:0005737
GO:0005829
GO:0006355
GO:0006605
GO:0007165
GO:0008104
GO:0016491
GO:0017053
GO:0019899
GO:0019904
GO:0031410
GO:0032991
GO:0035308
GO:0042470
GO:0042802
GO:0042826
GO:0043226
GO:0044877
GO:0045184
GO:0045744
GO:0045892
GO:0048471
GO:0050815
GO:0051219
GO:0051220
GO:0098772
ILMN_2490479
ILMN_2935362
Msa.10201.0_f_at
mMC011385
Participates
as an input of
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Mus musculus)
p-S54,92,203-BRF1 binds 14-3-3 (Mus musculus)
p-S92,203-BRF1 binds 14-3-3 (Mus musculus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Mus musculus)
as a component of
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Mus musculus)
Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Mus musculus)
Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Mus musculus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
B-Raf complex [cytosol] (Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Mus musculus)
14-3-3 beta,alpha dimer [cytosol] (Mus musculus)
as a member of
14-3-3 beta, zeta [cytosol] (Mus musculus)
Inferred From
YWHAB [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_061223.2
,
XP_006499972.1
ENSEMBL
ENSMUST00000018470
,
ENSMUSP00000018470
,
ENSMUSG00000018326
PRO
Q9CQV8
GlyGen
Q9CQV8
MGI
1891917
PDB
4GNT
,
5WFX
,
5F74
,
5WFU
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S006
1
LRRK2 [cytosol]
(R-MMU-5661173)
0.677
6
UniProt:P16054
2
PRKCE [cytosol]
(R-MMU-58202)
phospho-p-T566,T710,S729-PRKCE [plasma membrane]
(R-MMU-198260)
0.643
5
UniProt:P35569 Irs1
8
p-Irs1 [cytosol]
(R-MMU-2671869)
phospho-Irs1 [plasma membrane]
(R-MMU-2445090)
Irs1 [plasma membrane]
(R-MMU-2425392)
Phospho-IRS1 (by NTRK1) [cytosol]
(R-MMU-198285)
Irs1 [cytosol]
(R-MMU-198257)
Irs1 [cytosol]
(R-MMU-74769)
phospho-Irs1 [cytosol]
(R-MMU-74772)
phospho-Irs1 [plasma membrane]
(R-MMU-198366)
0.527
2
UniProt:Q91YE8 SYNP2
0.482
3
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