Reactome | Ndufa10 [mitochondrial inner membrane]

Ndufa10 [mitochondrial inner membrane]

Stable Identifier

R-MMU-163937

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

mitochondrial inner membrane

Synonyms

NDUFA10, Q99LC3

Locations in the PathwayBrowser

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Metabolism (Mus musculus)

- Aerobic respiration and respiratory electron transport (Mus musculus)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Mus musculus)
    - Respiratory electron transport (Mus musculus)
      - Complex I biogenesis (Mus musculus)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        980kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Mus musculus)
        
        980kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Complex I [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Mus musculus)
        
        Complex I [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q99LC3

Gene Names

Ndufa10

Reference Genes

BioGPS Gene:67273 Ndufa10

ENSEMBL:ENSMUSG00000026260

ENSEMBL:ENSMUSG00000026260.13 Ndufa10

KEGG Gene (Mus musculus):67273 Ndufa10

Monarch:67273 Ndufa10

NCBI Gene:67273 Ndufa10

UCSC:Q99LC3 Ndufa10

Reference Transcript

RefSeq:NM_024197.1 Ndufa10

Other Identifiers

10356657

1418068_at

1448934_at

160284_at

17225564

4314840

4333761

4436837

4454450

4620909

4913266

5125330

5227834

5285445

5392163

5394355

5413261

5555091

5567721

67273

A_51_P272123

A_66_P133882

GE40562

GO:0003824

GO:0005215

GO:0005737

GO:0005739

GO:0005743

GO:0005747

GO:0005759

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0016491

GO:0032981

GO:0042776

GO:0043209

GO:0043226

GO:0055086

GO:0065003

GO:0070469

GO:1901135

ILMN_2477629

ILMN_2657946

aa512555_at

aa512555_g_at

mMC008591

mMR028106

Participates

as a component of

NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)

Inferred From

NDUFA10 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_077159.1

Ensembl

ENSMUST00000027478, ENSMUSP00000027478, ENSMUSG00000026260

PRO

Q99LC3

MGI

1914523

PDB

7PSA, 7AK5, 6ZR2, 7AK6, 6G72, 6G2J, 7B93, 8OM1, 6ZTQ, 8OLT

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