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Terf1 [nucleoplasm]
Stable Identifier
R-MMU-164618
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
TERF1, P70371
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Chromosome Maintenance (Mus musculus)
Telomere Maintenance (Mus musculus)
Extension of Telomeres (Mus musculus)
Telomere C-strand (Lagging Strand) Synthesis (Mus musculus)
Disassociation of Processive Complex and Completed Telomere End (Mus musculus)
Extended And Processed Telomere End [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Polymerase switching on the C-strand of the telomere (Mus musculus)
Formation of Processive Complex on the C-strand of the telomere (Mus musculus)
Processive complex loaded on telomere [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive synthesis on the C-strand of the telomere (Mus musculus)
Formation of C-strand Okazaki fragments (Mus musculus)
Processive complex loaded on telomere [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Formation of the Flap Intermediate on the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Joining of adjacent Okazaki fragments of the C-strand (Mus musculus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Removal of the Flap Intermediate from the C-strand (Mus musculus)
RPA binds to the Flap on the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Recruitment of DNA2 endonuclease to the C strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Removal of remaining Flap from the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomere C-strand synthesis initiation (Mus musculus)
DNA polymerase:primase binds G-strand of the telomere (Mus musculus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Mus musculus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Mus musculus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomere Extension By Telomerase (Mus musculus)
Alignment Of The RNA Template On The Telomeric Chromosome End (Mus musculus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
CDK2:CCNA phosphorylates TERF2 (Mus musculus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Disassociation of Telomerase RNP and the Chromosome End (Mus musculus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Elongation Of The Telomeric Chromosome End (Mus musculus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Elongation of Extended Telomeric Chromosome End (Mus musculus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
PP6-PPP6R3 dephosphorylates TERF2 (Mus musculus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Mus musculus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Mus musculus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Inhibition of DNA recombination at telomere (Mus musculus)
ATRX:DAXX binds to subtelomeric chromosomal regions (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Histone H3.3 deposition at telomere (Mus musculus)
Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
DNA Damage/Telomere Stress Induced Senescence (Mus musculus)
Telomere shortening during replicative exhaustion (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
DNA Repair (Mus musculus)
Base Excision Repair (Mus musculus)
Base-Excision Repair, AP Site Formation (Mus musculus)
Depurination (Mus musculus)
Cleavage of the damaged purine (Mus musculus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Mus musculus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
Recognition and association of DNA glycosylase with site containing an affected purine (Mus musculus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
TERF1 homodimer [nucleoplasm] (Mus musculus)
Terf1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P70371 Terf1
Gene Names
Terf1, Trf1
Chain
initiator methionine:, chain:2-421
Reference Genes
BioGPS Gene:21749 Terf1
ENSEMBL:ENSMUSG00000025925.15 Terf1
KEGG Gene (Mus musculus):21749 Terf1
Monarch:21749 Terf1
NCBI Gene:21749 Terf1
UCSC:P70371 Terf1
Reference Transcript
RefSeq:NM_009352.3 Terf1
Other Identifiers
10344939
1418380_at
1431332_a_at
160879_at
17211243
21749
4454674
4515107
4569724
4761252
4854812
4922392
4983786
4994518
5107350
5266056
5299498
5396380
5494461
5511973
99920_at
A_51_P482464
A_55_P2000304
GE33787
GO:0000723
GO:0000781
GO:0000783
GO:0001650
GO:0003677
GO:0003691
GO:0003720
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005819
GO:0005856
GO:0006260
GO:0007004
GO:0007049
GO:0007059
GO:0008017
GO:0008092
GO:0008156
GO:0008301
GO:0016233
GO:0016604
GO:0016740
GO:0022414
GO:0032200
GO:0032206
GO:0032211
GO:0042162
GO:0042802
GO:0042803
GO:0043226
GO:0045141
GO:0051301
GO:0060090
GO:0061820
GO:0065003
GO:0070187
GO:0071532
GO:0098505
GO:0140013
GO:0140097
GO:1904792
GO:1904850
GO:1904911
GO:1905839
ILMN_1256480
U65586_s_at
mMC016242
Participates
as a component of
TERF1 homodimer [nucleoplasm] (Mus musculus)
Other forms of this molecule
Telomeric repeat-binding factor 1 [nucleoplasm]
Inferred From
TERF1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_033378.1
Ensembl
ENSMUSG00000025925
,
ENSMUST00000188371
,
ENSMUSP00000140744
PRO
P70371
MGI
109634
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6ZQJ5
1
DNA2 [nucleoplasm]
(R-MMU-68465)
0.576
4
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