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Tlr4 [plasma membrane]
Stable Identifier
R-MMU-166045
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
2xN4GlycoAsn-TLR4, Q9QUK6
Locations in the PathwayBrowser for interactor UniProt:Q3U0V2
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Heme signaling (Mus musculus)
Hemes:LY96 activates TLR4 (Mus musculus)
Tlr4 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9QUK6
Gene Names
Tlr4
Reference Genes
BioGPS Gene:21898 Tlr4
ENSEMBL:ENSMUSG00000039005
ENSEMBL:ENSMUSG00000039005.14 Tlr4
KEGG Gene (Mus musculus):21898 Tlr4
Monarch:21898 Tlr4
NCBI Gene:21898 Tlr4
UCSC:Q9QUK6 Tlr4
Reference Transcript
RefSeq:NM_021297.3 Tlr4
Other Identifiers
10505517
111295_at
1418162_at
1418163_at
1442827_at
17414836
21898
4376441
4877727
5073811
5289992
5535590
5572692
A_55_P2603039
A_66_P124806
GE37876
GO:0001530
GO:0001726
GO:0001774
GO:0001819
GO:0001875
GO:0001891
GO:0002218
GO:0002224
GO:0002246
GO:0002322
GO:0002376
GO:0002537
GO:0002730
GO:0002755
GO:0002758
GO:0003824
GO:0004888
GO:0005102
GO:0005515
GO:0005737
GO:0005768
GO:0005769
GO:0005886
GO:0006351
GO:0006355
GO:0006691
GO:0006809
GO:0006909
GO:0006954
GO:0006955
GO:0006979
GO:0007165
GO:0007250
GO:0007254
GO:0008289
GO:0009617
GO:0009897
GO:0009986
GO:0010008
GO:0010467
GO:0010572
GO:0010628
GO:0012501
GO:0014002
GO:0014004
GO:0014911
GO:0016020
GO:0016192
GO:0016787
GO:0022008
GO:0022600
GO:0023052
GO:0030154
GO:0030890
GO:0031410
GO:0031663
GO:0032496
GO:0032497
GO:0032680
GO:0032689
GO:0032700
GO:0032707
GO:0032715
GO:0032720
GO:0032722
GO:0032727
GO:0032728
GO:0032729
GO:0032731
GO:0032732
GO:0032733
GO:0032735
GO:0032736
GO:0032755
GO:0032757
GO:0032760
GO:0032874
GO:0034142
GO:0035666
GO:0036120
GO:0036211
GO:0038023
GO:0042060
GO:0042100
GO:0042116
GO:0042742
GO:0042802
GO:0042995
GO:0043032
GO:0043065
GO:0043123
GO:0043226
GO:0043235
GO:0043406
GO:0043548
GO:0045087
GO:0045342
GO:0045348
GO:0045429
GO:0045471
GO:0045576
GO:0045944
GO:0046330
GO:0046651
GO:0046696
GO:0046982
GO:0048471
GO:0048661
GO:0048856
GO:0048870
GO:0050135
GO:0050671
GO:0050727
GO:0050729
GO:0050731
GO:0050829
GO:0050877
GO:0050965
GO:0050966
GO:0051092
GO:0051403
GO:0051770
GO:0060089
GO:0060729
GO:0060907
GO:0061809
GO:0065003
GO:0070371
GO:0070373
GO:0070374
GO:0070427
GO:0070430
GO:0070431
GO:0070434
GO:0070542
GO:0071222
GO:0071223
GO:0071260
GO:0071346
GO:0098542
GO:0120163
GO:0140052
GO:1900017
GO:1900227
GO:1901224
GO:1903428
GO:1903974
GO:1904466
GO:1904646
GO:2000343
GO:2001238
ILMN_2690004
ILMN_2752966
mMC020916
Participates
as an input of
Hemes:LY96 activates TLR4 (Mus musculus)
as a component of
TLR4:Hemes:LY96 [plasma membrane] (Mus musculus)
TLR4:TLR6 [plasma membrane] (Mus musculus)
TLR4:LY96 [plasma membrane] (Mus musculus)
Other forms of this molecule
Tlr4 [endosome membrane]
Inferred From
2xN4GlycoAsn-TLR4 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
N4-glycosyl-L-asparagine at 526 (in Homo sapiens)
Coordinate
526
PsiMod Name
N4-glycosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to an N4-glycosyl-L-asparagine.
Name
N4-glycosyl-L-asparagine at 575 (in Homo sapiens)
Coordinate
575
PsiMod Name
N4-glycosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to an N4-glycosyl-L-asparagine.
Cross References
RefSeq
NP_067272.1
ZINC - Substances
TLR4_MOUSE
ZINC - Biogenic
TLR4_MOUSE
ZINC target
Q9QUK6
Ensembl
ENSMUSP00000045770
,
ENSMUSG00000039005
,
ENSMUST00000048096
PRO
Q9QUK6
MGI
96824
ZINC - Predictions - Purchasable
TLR4_MOUSE
PDB
5IJC
,
5IJB
,
3VQ1
,
7MLM
,
5IJD
,
3VQ2
,
2Z64
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9JHF9
3
Ly96 [extracellular region]
(R-MMU-9707658)
Ly96 [endosome membrane]
(R-MMU-2201307)
Ly96 [plasma membrane]
(R-MMU-166047)
0.817
8
UniProt:P22366
1
Myd88 [cytosol]
(R-MMU-166059)
0.564
2
UniProt:Q91Y57
5
SIGLEC7 [plasma membrane]
(R-MMU-197722)
SIGLEC8 [plasma membrane]
(R-MMU-197720)
SIGLEC12 [plasma membrane]
(R-MMU-197729)
SIGLEC9 [plasma membrane]
(R-MMU-197723)
SIGLEC9 [secretory granule membrane]
(R-MMU-6804775)
0.524
3
UniProt:Q3U0V2
1
TRADD [cytosol]
(R-MMU-66376)
0.499
3
UniProt:O35657
3
NEU1 [extracellular region]
(R-MMU-6806158)
NEU1 [specific granule lumen]
(R-MMU-6806148)
NEU1 [lysosomal lumen]
(R-MMU-1605788)
0.463
2
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