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Abi1 [cytosol]
Stable Identifier
R-MMU-1671643
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
ABI1, Q8CBW3
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Regulation of actin dynamics for phagocytic cup formation (Mus musculus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Mus musculus)
Mother filament:branching complex [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
ABL phosphorylates WAVEs (Mus musculus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
Detachment of WASP/WAVE (Mus musculus)
Mother filament:branching complex [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
p-ERK phosphorylates WAVEs and ABI (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate WASPs and WAVEs (Mus musculus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Mus musculus)
Mother filament:branching complex [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
ABL phosphorylates WAVEs (Mus musculus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
Detachment of WASP/WAVE (Mus musculus)
Mother filament:branching complex [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2, WASP, N-WASP [plasma membrane] (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
p-ERK phosphorylates WAVEs and ABI (Mus musculus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Mus musculus)
p-Y-WRC [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RHO GTPase cycle (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 binds effectors at the plasma membrane (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC2 GTPase cycle (Mus musculus)
RAC2 binds effectors at the plasma membrane (Mus musculus)
RAC2 plasma membrane effectors [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2 Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Mus musculus)
RAC2 plasma membrane effectors [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2 Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC3 GTPase cycle (Mus musculus)
RAC3 binds effectors at the plasma membrane (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE1 Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2 Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
RAC3:GTP:RAC3 effectors [plasma membrane] (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE1 Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
WAVE2 Regulatory Complex [cytosol] (Mus musculus)
ABI [cytosol] (Mus musculus)
Abi1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8CBW3
Gene Names
Abi1
Reference Genes
BioGPS Gene:11308 Abi1
ENSEMBL:ENSMUSG00000058835
ENSEMBL:ENSMUSG00000058835.15 Abi1
KEGG Gene (Mus musculus):11308 Abi1
Monarch:11308 Abi1
NCBI Gene:11308 Abi1
UCSC:Q8CBW3 Abi1
Reference Transcript
RefSeq:NM_001077193.3 Abi1
RefSeq:NM_001077190.3 Abi1
RefSeq:NM_007380.4 Abi1
RefSeq:NM_001077192.3 Abi1
Other Identifiers
101037_at
10480423
11308
1423177_a_at
1423178_at
1438506_s_at
1450890_a_at
17382156
4401919
4496311
4551303
4579676
4625843
4798459
4809996
4881592
4897302
4977594
5268523
5292028
5368548
5399549
5479143
5596824
A_30_P01026813
A_52_P157274
A_55_P2483261
GE33401
GO:0001756
GO:0005515
GO:0005634
GO:0005737
GO:0005856
GO:0014069
GO:0017124
GO:0023052
GO:0030027
GO:0030154
GO:0030175
GO:0030296
GO:0030426
GO:0031209
GO:0031252
GO:0032433
GO:0035591
GO:0035855
GO:0042995
GO:0043005
GO:0043226
GO:0045202
GO:0048813
GO:0048856
GO:0060090
GO:0072673
GO:0098772
GO:0098978
GO:0099527
ILMN_1234139
ILMN_2512032
ILMN_3094886
U17698_s_at
mMC008277
Participates
as a candidate of
RAC2 plasma membrane effectors [cytosol] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
as a member of
ABI [cytosol] (Mus musculus)
Other forms of this molecule
phospho-Abi1 [cytosol]
Inferred From
ABI1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_031406.2
,
NP_001070660.1
,
NP_001070658.1
,
NP_001070661.1
Ensembl
ENSMUSG00000058835
,
ENSMUST00000123948
,
ENSMUSP00000120462
,
ENSMUST00000114544
,
ENSMUST00000126112
,
ENSMUSP00000117335
,
ENSMUSP00000110191
,
ENSMUST00000140164
,
ENSMUSP00000120621
,
ENSMUST00000149719
,
ENSMUSP00000118491
PRO
Q8CBW3
MGI
104913
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