Reactome | Gna11 [plasma membrane]

Gna11 [plasma membrane]

Stable Identifier

R-MMU-167446

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

GNA11, P21278

Locations in the PathwayBrowser

Expand all

Hemostasis (Mus musculus)

- Platelet activation, signaling and aggregation (Mus musculus)
  - Signal amplification (Mus musculus)
    - ADP signalling through P2Y purinoceptor 1 (Mus musculus)
      - Dissociation of the P2Y purinoceptor 1:Gq complex (Mus musculus)
        
        ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
      - P2Y purinoceptor 1 activates MAP kinase p38 alpha (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
    - Thromboxane signalling through TP receptor (Mus musculus)
      - Activated TP receptor binds G-proten Gq (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
      - Dissociation of the TP:Gq complex (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
      - Gq activation by TP receptor (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
  - Thrombin signalling through proteinase activated receptors (PARs) (Mus musculus)
    - Thrombin-activated PARs activate Gq (Mus musculus)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
    - Thrombin-activated PARs binds G-protein Gq (Mus musculus)
      - Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
    - Thrombin-activated PARs:Gq (active) dissociate (Mus musculus)
      - G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna11 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P21278

Gene Names

Gna11

Reference Genes

BioGPS Gene:14672 Gna11

ENSEMBL:ENSMUSG00000034781

KEGG:mmu:14672 Gna11

Monarch:14672 Gna11

NCBI Gene:14672 Gna11

UCSC:P21278 Gna11

Reference Transcript

RefSeq:NM_010301.4 Gna11

Other Identifiers

102196_at

103411_at

10371230

1434254_at

1449144_at

14672

17243392

4310839

4440962

4460960

4547842

4566260

4872954

4968632

4981743

5234014

5238405

5313638

5396228

A_51_P498004

A_52_P366932

GE1543551

GE35473

GO:0001501

GO:0001508

GO:0001664

GO:0003824

GO:0003924

GO:0003925

GO:0005515

GO:0005525

GO:0005737

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007200

GO:0007207

GO:0007507

GO:0008217

GO:0016787

GO:0019001

GO:0030234

GO:0031683

GO:0032024

GO:0045202

GO:0045634

GO:0046872

GO:0047391

GO:0048066

GO:0048856

GO:0060158

GO:0071467

GO:0086100

GO:0098772

GO:0099105

GO:1904888

GO:1990806

ILMN_1254131

ILMN_2592852

ILMN_2745753

ILMN_2751072

ILMN_2751075

mMC006611

u37413_s_at

Participates

as a member of

as a candidate of

G(q) alpha 11,14,15,Q [plasma membrane] (Mus musculus)

Inferred From

GNA11 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034431.1

ENSEMBL

ENSMUSG00000034781, ENSMUST00000043604, ENSMUSP00000043190

PRO

P21278

GlyGen

P21278

MGI

95766

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