Reactome | Gna14 [plasma membrane]

Gna14 [plasma membrane]

Stable Identifier

R-MMU-167453

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

GNA14, P30677

Locations in the PathwayBrowser

Expand all

Hemostasis (Mus musculus)

- Platelet activation, signaling and aggregation (Mus musculus)
  - Signal amplification (Mus musculus)
    - ADP signalling through P2Y purinoceptor 1 (Mus musculus)
      - Dissociation of the P2Y purinoceptor 1:Gq complex (Mus musculus)
        
        ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
      - P2Y purinoceptor 1 activates MAP kinase p38 alpha (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
    - Thromboxane signalling through TP receptor (Mus musculus)
      - Activated TP receptor binds G-proten Gq (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
      - Dissociation of the TP:Gq complex (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
      - Gq activation by TP receptor (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
  - Thrombin signalling through proteinase activated receptors (PARs) (Mus musculus)
    - Thrombin-activated PARs activate Gq (Mus musculus)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
    - Thrombin-activated PARs binds G-protein Gq (Mus musculus)
      - Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
    - Thrombin-activated PARs:Gq (active) dissociate (Mus musculus)
      - G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Mus musculus)
        
        G protein-GTP [plasma membrane] (Mus musculus)
        
        G protein alpha:GTP complex [plasma membrane] (Mus musculus)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)
        
        Gna14 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P30677

Gene Names

Gna14

Reference Genes

BioGPS Gene:14675 Gna14

ENSEMBL:ENSMUSG00000024697

KEGG:mmu:14675 Gna14

Monarch:14675 Gna14

NCBI Gene:14675 Gna14

UCSC:P30677 Gna14

Reference Transcript

RefSeq:NM_008137.4 Gna14

Other Identifiers

10461856

1420385_at

1447791_s_at

1449848_at

14675

17357971

4380529

4406004

4432243

4506599

4547798

4749098

4961844

5102406

5132418

5227060

5365596

5423581

5491203

95364_at

A_51_P110323

A_66_P106611

GE34493

GO:0001664

GO:0003824

GO:0003924

GO:0005525

GO:0005834

GO:0007165

GO:0007186

GO:0016787

GO:0019001

GO:0031683

GO:0046872

ILMN_2597778

M80631_s_at

mMC006986

Participates

as a candidate of

G(q) alpha 11,14,15,Q [plasma membrane] (Mus musculus)

as a member of

G-protein alpha (q/11/14/15) [plasma membrane] (Mus musculus)

Inferred From

GNA14 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032163.3

ENSEMBL

ENSMUSP00000025602, ENSMUST00000025602, ENSMUSG00000024697

PRO

P30677

GlyGen

P30677

MGI

95769

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