Reactome | Sh2b1 [cytosol]

Sh2b1 [cytosol]

Stable Identifier

R-MMU-1675482

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

SH2B1-2, Q91ZM2

Locations in the PathwayBrowser for interactor UniProt:Q62120

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External Reference Information

External Reference

UniProt:Q91ZM2 Sh2b1

Gene Names

Sh2b1, Sh2bpsm1

Chain

chain:1-756

Reference Genes

BioGPS Gene:20399 Sh2b1

ENSEMBL:ENSMUSG00000030733.11 Sh2b1

KEGG Gene (Mus musculus):20399 Sh2b1

Monarch:20399 Sh2b1

NCBI Gene:20399 Sh2b1

UCSC:Q91ZM2 Sh2b1

Reference Transcript

Other Identifiers

101843_at

10567903

1431438_at

1448874_a_at

17496237

20399

4342912

4418070

4425410

4500506

4573197

4580647

4613577

4681446

4692232

4700532

4733860

4781077

4914187

4915951

5013959

5038347

5053289

5180960

5238927

5255522

5281124

5372024

5387610

5450435

5467022

5498819

5514693

5581454

A_52_P576100

GE36074

GO:0000278

GO:0001726

GO:0005068

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0007165

GO:0007169

GO:0016020

GO:0023052

GO:0030032

GO:0035556

GO:0035591

GO:0043226

GO:0045840

GO:0048870

GO:0060090

GO:0060391

GO:0140014

GO:2000278

ILMN_1256412

ILMN_3139354

mMC015918

Participates

as an input of

SH2B binds JAK2 (Mus musculus)

as a component of

PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Mus musculus)

Other forms of this molecule

Sh2b1 [cytosol]

Inferred From

SH2B1-2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001276471.1, NP_001276467.1, NP_001276470.1, XP_006507543.1, XP_006507545.1, NP_001276468.1, NP_035493.2, NP_001074928.1, XP_006507550.1, XP_006507544.1, XP_006507548.1, XP_006507541.1, NP_001276469.1

Ensembl

ENSMUSP00000145554, ENSMUSP00000032978, ENSMUSP00000145754, ENSMUSP00000145842, ENSMUSP00000145953, ENSMUST00000206664, ENSMUST00000205497, ENSMUST00000205733, ENSMUST00000205889, ENSMUST00000032978, ENSMUSP00000146121, ENSMUST00000205340, ENSMUST00000205440, ENSMUSG00000030733, ENSMUSP00000146282

PRO

Q91ZM2

MGI

1201407

PDB

8ATK, 2HDV, 2HDX

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62120 Jak2	11	phospho-p-Y1007,Y1008-JAK2 [cytosol] (R-MMU-9005327) p-Jak2 [cytosol] (R-MMU-8950633) phospho-p-JAK2 [cytosol] (R-MMU-210621) phospho-p-Y813-JAK2 [cytosol] (R-MMU-997248) JAK2 [endosome lumen] (R-MMU-2002372) JAK2 [cytosol] (R-MMU-210620) phospho-p-Y1007-JAK2 [cytosol] (R-MMU-873799) Jak2 [cytosol] (R-MMU-205743) phospho-p-12Y-JAK2 [cytosol] (R-MMU-2586516) p-Y1007-Jak2 [cytosol] (R-MMU-997296) p-12Y-Jak2 [cytosol] (R-MMU-2586515)	0.667	3

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