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Tinf2 [nucleoplasm]
Stable Identifier
R-MMU-174883
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
TINF2, Q9QXG9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Chromosome Maintenance (Mus musculus)
Telomere Maintenance (Mus musculus)
Extension of Telomeres (Mus musculus)
Telomere C-strand (Lagging Strand) Synthesis (Mus musculus)
Disassociation of Processive Complex and Completed Telomere End (Mus musculus)
Extended And Processed Telomere End [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Polymerase switching on the C-strand of the telomere (Mus musculus)
Formation of Processive Complex on the C-strand of the telomere (Mus musculus)
Processive complex loaded on telomere [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Mus musculus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive synthesis on the C-strand of the telomere (Mus musculus)
Formation of C-strand Okazaki fragments (Mus musculus)
Processive complex loaded on telomere [nucleoplasm] (Mus musculus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Formation of the Flap Intermediate on the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Joining of adjacent Okazaki fragments of the C-strand (Mus musculus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Removal of the Flap Intermediate from the C-strand (Mus musculus)
RPA binds to the Flap on the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Recruitment of DNA2 endonuclease to the C strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Removal of remaining Flap from the C-strand (Mus musculus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomere C-strand synthesis initiation (Mus musculus)
DNA polymerase:primase binds G-strand of the telomere (Mus musculus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Mus musculus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Mus musculus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomere Extension By Telomerase (Mus musculus)
Alignment Of The RNA Template On The Telomeric Chromosome End (Mus musculus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
CDK2:CCNA phosphorylates TERF2 (Mus musculus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Disassociation of Telomerase RNP and the Chromosome End (Mus musculus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Elongation Of The Telomeric Chromosome End (Mus musculus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Elongation of Extended Telomeric Chromosome End (Mus musculus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
PP6-PPP6R3 dephosphorylates TERF2 (Mus musculus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Mus musculus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Mus musculus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Inhibition of DNA recombination at telomere (Mus musculus)
ATRX:DAXX binds to subtelomeric chromosomal regions (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Histone H3.3 deposition at telomere (Mus musculus)
Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
DNA Damage/Telomere Stress Induced Senescence (Mus musculus)
Telomere shortening during replicative exhaustion (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
DNA Repair (Mus musculus)
Base Excision Repair (Mus musculus)
Base-Excision Repair, AP Site Formation (Mus musculus)
Depurination (Mus musculus)
Cleavage of the damaged purine (Mus musculus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Mus musculus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
Recognition and association of DNA glycosylase with site containing an affected purine (Mus musculus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Tinf2 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9QXG9 Tinf2
Gene Names
Tinf2, Tin2
Chain
initiator methionine:, chain:2-341
Participates
as a component of
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Mus musculus)
Shelterin complex [nucleoplasm] (Mus musculus)
Other forms of this molecule
TERF1-interacting nuclear factor 2 [nucleoplasm]
Inferred From
TINF2 [nucleoplasm]
(Homo sapiens)
Cross References
PRO
Q9QXG9
MGI
107246
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