Reactome | Cd86 [plasma membrane]

Cd86 [plasma membrane]

Stable Identifier

R-MMU-179784

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CD86, P42082

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - Negative regulation of the PI3K/AKT network (Mus musculus)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
        
        PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
        
        Activator:PI3K [plasma membrane] (Mus musculus)
        
        CD28:PI3K [plasma membrane] (Mus musculus)
        
        phospho CD28:B7-1/B7-2 [plasma membrane] (Mus musculus)
        
        B7-1 homodimer/ B7-2 [plasma membrane] (Mus musculus)
        
        Cd86 [plasma membrane] (Mus musculus)
    - PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
      - Activator:PI3K [plasma membrane] (Mus musculus)
        
        CD28:PI3K [plasma membrane] (Mus musculus)
        
        phospho CD28:B7-1/B7-2 [plasma membrane] (Mus musculus)
        
        B7-1 homodimer/ B7-2 [plasma membrane] (Mus musculus)
        
        Cd86 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P42082

Gene Names

Cd86

Reference Genes

BioGPS Gene:12524 Cd86

ENSEMBL:ENSMUSG00000022901

ENSEMBL:ENSMUSG00000022901.14 Cd86

KEGG Gene (Mus musculus):12524 Cd86

Monarch:12524 Cd86

NCBI Gene:12524 Cd86

UCSC:P42082 Cd86

Reference Transcript

Other Identifiers

102830_at

102831_s_at

10439312

114806_at

12524

1420404_at

1449858_at

17330203

4326318

4345413

4385541

4604182

4684433

4780784

4807737

4810855

4996042

5463536

5532565

5538520

A_51_P174723

A_52_P145861

A_55_P1971951

GE37359

GO:0002224

GO:0002250

GO:0002376

GO:0002639

GO:0002668

GO:0005102

GO:0005515

GO:0005576

GO:0005615

GO:0005815

GO:0005856

GO:0005886

GO:0006955

GO:0007155

GO:0007166

GO:0007202

GO:0009897

GO:0009986

GO:0016020

GO:0023035

GO:0023052

GO:0031295

GO:0034138

GO:0034451

GO:0036211

GO:0042102

GO:0042104

GO:0042110

GO:0042113

GO:0043226

GO:0043231

GO:0048018

GO:0048856

GO:0051607

GO:0070062

GO:0071222

GO:0098542

GO:0098772

GO:1901224

GO:1990051

ILMN_1216386

ILMN_1217041

ILMN_2743244

l25606_s_at

mMC003612

Participates

as an input of

CD28 homodimer binds B7-2 monomer (Mus musculus)

as a component of

CD28:B7-2 [plasma membrane] (Mus musculus)

as a member of

B7-1 homodimer/ B7-2 [plasma membrane] (Mus musculus)

Inferred From

CD86 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_062261.3, XP_011244114.1

Ensembl

ENSMUSP00000087047, ENSMUST00000089620, ENSMUSG00000022901

PRO

P42082

MGI

101773

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