Reactome | Tbk1 [cytosol]

Tbk1 [cytosol]

Stable Identifier

R-MMU-1810477

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9WUN2 Tbk1

Gene Names

Tbk1

Chain

chain:1-729

Reference Genes

BioGPS Gene:56480 Tbk1

ENSEMBL:ENSMUSG00000020115 Tbk1

KEGG Gene (Mus musculus):56480 Tbk1

Monarch:56480 Tbk1

NCBI Gene:56480 Tbk1

UCSC:Q9WUN2 Tbk1

Reference Transcript

RefSeq:NM_019786.4 Tbk1

Other Identifiers

10372853

1422469_at

1460315_s_at

17245488

215536

4335136

4345558

4355811

4531251

4551086

4735410

4817256

4860585

4893102

4895715

4932712

4954614

4JL9

4JLC

5080532

5083240

5092588

5118097

5223573

5308606

5331374

5337742

5419176

5513820

56480

98087_at

A0A1W2P6W7

A0A1W2P835

A1L361

A_51_P169850

A_52_P532029

AAD34590

AAF05990

AAI29911

AAI29912

AF145705

AF191839

AK004269

AK004649

BAB23244

BAB23440

BC129910

BC129911

CCDS24212

CH466578

EDL24420

ENSMUSG00000020115

ENSMUSP00000020316

ENSMUST00000020316

ENSMUST00000020316.3

EntrezGene:56480

EntrezGene:Tbk1

GE37612

GO:0000166

GO:0002218

GO:0002376

GO:0003674

GO:0003676

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006464

GO:0006468

GO:0006914

GO:0006950

GO:0007165

GO:0008150

GO:0008283

GO:0009056

GO:0009058

GO:0010468

GO:0010629

GO:0016235

GO:0016239

GO:0016301

GO:0016310

GO:0016740

GO:0018105

GO:0018107

GO:0019899

GO:0019903

GO:0031323

GO:0032479

GO:0032727

GO:0032728

GO:0034641

GO:0042802

GO:0043123

GO:0043167

GO:0043226

GO:0044565

GO:0045087

GO:0045359

GO:0045944

GO:0050830

GO:0051219

GO:0051607

GO:0060340

GO:1904417

ILMN_1241535

IPR000719

IPR011009

IPR017441

IPR041087

IPR041309

MGI:1929658

mMC018910

NM_019786

NP_062760

PF00069

PF18394

PF18396

SM00220

Tbk1

Tbk1-201

UPI0000021823

XR_001779563

Participant Of

input

hasMember

IKK related kinases TBK1/IKK epsilon [cytosol]

hasComponent

Other forms of this molecule

phospho-p-S172-TBK1 [plasma membrane]

phospho-p-S172-TBK1 [endosome membrane]

phospho-Q9WUN2 [cytosol]

phospho-pS-172,K48polyUb-TBK1 [cytosol]

p-S172-Tbk1 [cytosol]

Inferred From

TBK1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_062760.3

ZINC - Substances

TBK1_MOUSE

ZINC target

Q9WUN2

PRO

Q9WUN2

ZINC - Predictions - Purchasable

TBK1_MOUSE

PDB

6O8C, 4JL9, 4JLC

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P70347	2	TANK [cytosol] (R-MMU-933407) K63polyUb-TANK [cytosol] (R-MMU-5362480)	0.75	7
UniProt:Q9WUN2 Tbk1	6	phospho-p-S172-TBK1 [endosome membrane] (R-MMU-450290) phospho-p-S172-TBK1 [plasma membrane] (R-MMU-936983) phospho-Q9WUN2 [cytosol] (R-MMU-9008705) phospho-pS-172,K48polyUb-TBK1 [cytosol] (R-MMU-3249397) Tbk1 [cytosol] (R-MMU-1810477) p-S172-Tbk1 [cytosol] (R-MMU-1810465)	0.719	5
UniProt:Q80UF7	1	TICAM1 [cytosol] (R-MMU-166170)	0.589	2
UniProt:Q3TBT3	5	TMEM173 [secretory granule membrane] (R-MMU-6804798) TMEM173 [plasma membrane] (R-MMU-6804815) K63polyUb-STING [cytoplasmic vesicle membrane] (R-MMU-3248021) K63polyUb-STING [endoplasmic reticulum membrane] (R-MMU-3134805) TMEM173 [endoplasmic reticulum membrane] (R-MMU-1834940)	0.564	3
UniProt:A2A9T0 TBKB1			0.499	2
UniProt:O41932 O41932			0.463	3

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