Formation of Cry:Per:Kinase complex

Stable Identifier
R-MMU-1856952
Type
Reaction [omitted]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Formation of Cry:Per:Kinase complex
Cryptochrome, Period, and kinase (CKIepsilon or CKIdelta) form a ternary complex.
Literature References
PubMed ID Title Journal Year
10428031 mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

Kume, K, Zylka, MJ, Hastings, MH, Reppert, SM, Maywood, ES, Shearman, LP, Jin, X, Sriram, S, Weaver, DR

Cell 1999
11875063 The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon

Eide, EJ, Vielhaber, EL, Virshup, DM, Hinz, WA

J Biol Chem 2002
25127877 Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex

Zheng, N, Green, CB, Rosensweig, C, Nangle, SN, Tei, H, Koike, N, Takahashi, JS

Elife 2014
19948962 Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock

Yoo, S, Lee, C, Chen, R, Lee, H, Lee, Y

Proc Natl Acad Sci U S A 2009
14701732 Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock

Reppert, SM, Lee, C, Weaver, DR

Mol Cell Biol 2004
10848614 Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

Eide, E, Virshup, DM, Vielhaber, E, Gao, ZH, Rivers, A

Mol Cell Biol 2000
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