Reactome | FGF10 activates Ptf1 expression in early pancreatic buds

FGF10 activates Ptf1 expression in early pancreatic buds

Stable Identifier

R-MMU-190093

Type

Reaction [omitted]

Species

Mus musculus

Compartment

nucleoplasm

General

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FGF10 activates Ptf1 expression in early pancreatic buds

Fgf10-/- embryos have markedly reduced Ptf1 mRNA expression in the midgut regions containing the pancreatic buds, while Fgf10 induces Ptf1 mRNA in pancreatic bud explants.

Literature References

PubMed ID	Title	Journal	Year
16386727	An endothelial-mesenchymal relay pathway regulates early phases of pancreas development Jacquemin, P, Yoshitomi, H, Kashima, Y, Rousseau, GG, Lemaigre, FP, Zaret, KS	Dev Biol	2006