FGF10 activates Ptf1 expression in early pancreatic buds

Stable Identifier
R-MMU-190093
Type
Reaction [omitted]
Species
Mus musculus
Compartment
General
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FGF10 activates Ptf1 expression in early pancreatic buds

Fgf10-/- embryos have markedly reduced Ptf1 mRNA expression in the midgut regions containing the pancreatic buds, while Fgf10 induces Ptf1 mRNA in pancreatic bud explants.

Literature References
PubMed ID Title Journal Year
16386727 An endothelial-mesenchymal relay pathway regulates early phases of pancreas development

Jacquemin, P, Yoshitomi, H, Kashima, Y, Rousseau, GG, Lemaigre, FP, Zaret, KS

Dev Biol 2006
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