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Microtubule [cytosol]
Stable Identifier
R-MMU-190599
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
Selective autophagy (Mus musculus)
Aggrephagy (Mus musculus)
Aggresome dissociates from dynein and microtubule (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
PolyUb-Misfolded proteins bind vimentin to form aggresome (Mus musculus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Nuclear Envelope (NE) Reassembly (Mus musculus)
Sealing of the nuclear envelope (NE) by ESCRT-III (Mus musculus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
ESPL1 (Separase) cleaves centromeric cohesin (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Separation of sister chromatids (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Mitotic Prometaphase (Mus musculus)
EML4 and NUDC in mitotic spindle formation (Mus musculus)
EML4 binds to microtubules (Mus musculus)
EML4 homotrimer:Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
EML4 recruits NUDC to mitotic spindle (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Recruitment of NuMA to mitotic centrosomes (Mus musculus)
Association of NuMA with microtubules (Mus musculus)
Microtubule [cytosol] (Mus musculus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Resolution of Sister Chromatid Cohesion (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Kinetochore assembly (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
PP2A-B56 dephosphorylates centromeric cohesin (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Phosphorylation of cohesin by PLK1 at centromeres (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Mus musculus)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Mus musculus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Mus musculus)
MAPRE1:microtubule plus end [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
MAPRE1:microtubule plus end [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
GTSE1 binds microtubule lattice in interphase cells (Mus musculus)
GTSE1:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Mus musculus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Mus musculus)
MAPRE1:microtubule plus end [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
MAPRE1:microtubule plus end [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Mus musculus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
L1CAM interactions (Mus musculus)
Recycling pathway of L1 (Mus musculus)
Reinsertion of L1 into the plasma membrane (Mus musculus)
AP2 clathrin:L1:KIF4:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Hemostasis (Mus musculus)
Factors involved in megakaryocyte development and platelet production (Mus musculus)
Kinesins (Mus musculus)
Kinesins bind microtubules (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Kinesins move along microtubules consuming ATP (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
MHC class II antigen presentation (Mus musculus)
Transport of antigen loaded MHC II molecules to surface (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Kinesins:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Antiviral mechanism by IFN-stimulated genes (Mus musculus)
PKR-mediated signaling (Mus musculus)
p-PKR dimer phosphorylates MAPT (Mus musculus)
MAPT-8:Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Transport to the Golgi and subsequent modification (Mus musculus)
ER to Golgi Anterograde Transport (Mus musculus)
COPI-mediated anterograde transport (Mus musculus)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Carboxyterminal post-translational modifications of tubulin (Mus musculus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Mus musculus)
Microtubule [cytosol] (Mus musculus)
TTLLs polyglutamylate tubulin (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RHO GTPases activate IQGAPs (Mus musculus)
IQGAP1 binds CLIP1 and microtubules (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
ER to Golgi Anterograde Transport (Mus musculus)
COPI-mediated anterograde transport (Mus musculus)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Gap junction trafficking and regulation (Mus musculus)
Gap junction trafficking (Mus musculus)
Gap junction assembly (Mus musculus)
Transport of connexons to the plasma membrane (Mus musculus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Mus musculus)
Association of Golgi transport vesicles with microtubules (Mus musculus)
Microtubule [cytosol] (Mus musculus)
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Intra-Golgi and retrograde Golgi-to-ER traffic (Mus musculus)
Golgi-to-ER retrograde transport (Mus musculus)
COPI-dependent Golgi-to-ER retrograde traffic (Mus musculus)
Retrograde COPI vesicles bind kinesin and microtubules (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
COPI-independent Golgi-to-ER retrograde traffic (Mus musculus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Mus musculus)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
Microtubule [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 13
Microtubule protofilament [cytosol]
(Mus musculus)
Participates
as an input of
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Mus musculus)
TTLLs polyglutamylate tubulin (Mus musculus)
Kinesins bind microtubules (Mus musculus)
EML4 binds to microtubules (Mus musculus)
Association of NuMA with microtubules (Mus musculus)
Kinetochore capture of astral microtubules (Mus musculus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Mus musculus)
IQGAP1 binds CLIP1 and microtubules (Mus musculus)
GTSE1 binds microtubule lattice in interphase cells (Mus musculus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)
Association of Golgi transport vesicles with microtubules (Mus musculus)
as a component of
Kinesins:Dynactin:microtubule [cytosol] (Mus musculus)
Kinesins:microtubule [cytosol] (Mus musculus)
AP2 clathrin:L1:KIF4:microtubule [cytosol] (Mus musculus)
Dynein:Dynactin:microtubule [cytosol] (Mus musculus)
MAPT-8:Microtubule [cytosol] (Mus musculus)
EML4 homotrimer:Microtubule [cytosol] (Mus musculus)
Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Mus musculus)
GTSE1:microtubule [cytosol] (Mus musculus)
MAPRE1:microtubule plus end [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
as an output of
Reinsertion of L1 into the plasma membrane (Mus musculus)
p-PKR dimer phosphorylates MAPT (Mus musculus)
Aggresome dissociates from dynein and microtubule (Mus musculus)
Inferred From
Microtubule [cytosol]
(Homo sapiens)
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