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RHOA [cytosol]
Stable Identifier
R-MMU-194866
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q9QUI0
Locations in the PathwayBrowser
Expand all
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
GPVI-mediated activation cascade (Mus musculus)
VAV1 is a GEF for Rho/Rac family GTPases (Mus musculus)
VAV1 Rho/Rac effectors:GDP [cytosol] (Mus musculus)
VAV1 effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
VAV1 Rho/Rac effectors:GTP [cytosol] (Mus musculus)
VAV1 effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
VAV2 is a GEF for Rho/Rac family kinases (Mus musculus)
VAV2 Rho/Rac effectors:GDP [cytosol] (Mus musculus)
VAV2 effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
VAV2 Rho/Rac effectors:GTP [cytosol] (Mus musculus)
VAV2 effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
VAV3 is a GEF for Rho/Rac family kinases (Mus musculus)
VAV3 Rho/Rac effectors:GDP [cytosol] (Mus musculus)
VAV3 effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
VAV3 Rho/Rac effectors:GTP [cytosol] (Mus musculus)
VAV3 effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Deubiquitination (Mus musculus)
Ovarian tumor domain proteases (Mus musculus)
OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Mus musculus)
OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Mus musculus)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Non-Receptor Tyrosine Kinases (Mus musculus)
Signaling by PTK6 (Mus musculus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Mus musculus)
ARHGAP35 stimulates RHOA GTPase activity (Mus musculus)
RHOA [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Mus musculus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
ROCK1,ROCK2 are activated (Mus musculus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
DAAM1 recruits GTP-bound RHOA (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
ppDVL:DAAM1:RHOA:GTP [cytosol] (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
RHO GTPase cycle (Mus musculus)
RHOA GTPase cycle (Mus musculus)
GDIs block activation of RHOA (Mus musculus)
RHOA GDIs:RHOA:GDP [cytosol] (Mus musculus)
RHOA:GDP [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
RHOC GTPase cycle (Mus musculus)
RHOC binds effectors at the plasma membrane (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
RHOC:GTP:RHOC effectors [plasma membrane] (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
PCP/CE pathway (Mus musculus)
DAAM1 recruits GTP-bound RHOA (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
ppDVL:DAAM1:RHOA:GTP [cytosol] (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
RHOA [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9QUI0 Rhoa
Gene Names
Rhoa, Arha, Arha2
Chain
chain:1-190, propeptide:191-193
Reference Genes
BioGPS Gene:11848 Rhoa
KEGG:mmu:11848 Rhoa
Monarch:11848 Rhoa
NCBI Gene:11848 Rhoa
UCSC:Q9QUI0 Rhoa
Reference Transcript
RefSeq:NM_001313962.1 Rhoa
RefSeq:NM_001313961.1 Rhoa
RefSeq:NM_016802.5 Rhoa
Other Identifiers
101112_g_at
101113_at
10515493
10588893
11848
1437628_s_at
1443768_at
1450632_at
17521673
4409016
4459617
4482078
4508800
4565011
4583367
4633409
4674876
4685482
4710267
4815940
4823631
4892106
4966430
4969402
4975127
5055662
5185759
5203049
5207893
5220605
5244811
5298202
5390491
5551470
5553686
A_52_P110965
A_52_P428496
GE42745
GO:0000902
GO:0001764
GO:0001822
GO:0001998
GO:0002363
GO:0002376
GO:0003013
GO:0003100
GO:0003189
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005634
GO:0005737
GO:0005739
GO:0005768
GO:0005829
GO:0005856
GO:0005886
GO:0005938
GO:0006355
GO:0006357
GO:0007010
GO:0007019
GO:0007155
GO:0007160
GO:0007163
GO:0007229
GO:0007264
GO:0007266
GO:0007519
GO:0008092
GO:0009410
GO:0009898
GO:0010812
GO:0010975
GO:0010977
GO:0012501
GO:0016020
GO:0016477
GO:0016787
GO:0017022
GO:0019003
GO:0019901
GO:0019904
GO:0021795
GO:0021861
GO:0030027
GO:0030036
GO:0030154
GO:0030307
GO:0030334
GO:0030424
GO:0030425
GO:0030496
GO:0030521
GO:0030838
GO:0031098
GO:0031122
GO:0031410
GO:0031982
GO:0032154
GO:0032467
GO:0032587
GO:0032956
GO:0033144
GO:0033688
GO:0034329
GO:0034330
GO:0034446
GO:0035385
GO:0036089
GO:0038027
GO:0042476
GO:0042995
GO:0043025
GO:0043123
GO:0043124
GO:0043149
GO:0043197
GO:0043226
GO:0043296
GO:0043297
GO:0043366
GO:0043525
GO:0043542
GO:0043931
GO:0044319
GO:0045198
GO:0045665
GO:0045666
GO:0045792
GO:0045987
GO:0046039
GO:0046638
GO:0048856
GO:0048870
GO:0050773
GO:0050886
GO:0050919
GO:0051022
GO:0051301
GO:0051496
GO:0051924
GO:0051964
GO:0055086
GO:0061024
GO:0061430
GO:0070507
GO:0071222
GO:0071345
GO:0071526
GO:0071803
GO:0071902
GO:0071944
GO:0090051
GO:0090307
GO:0090324
GO:0097049
GO:0097498
GO:0098772
GO:0098794
GO:0098978
GO:0099159
GO:1901135
GO:1902766
GO:1903427
GO:1903673
GO:1904695
GO:1904706
GO:1904753
GO:1904996
GO:1905244
GO:1905274
GO:1990869
GO:2000177
GO:2000406
GO:2000672
ILMN_1219914
ILMN_2683018
ILMN_2728181
Msa.3406.0_s_at
aa161790_s_at
mMC025757
mMR026599
mMR028236
Participates
as a component of
RHOA:GDP [cytosol] (Mus musculus)
RHOA:GTP:Mg2+ [cytosol] (Mus musculus)
as a candidate of
RHOC effectors [cytosol] (Mus musculus)
VAV1 effectors [cytosol] (Mus musculus)
as a member of
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Mus musculus)
VAV3 effectors [cytosol] (Mus musculus)
VAV2 effectors [cytosol] (Mus musculus)
Other forms of this molecule
RHOA [endoplasmic reticulum membrane]
RHOA [secretory granule membrane]
RHOA [ficolin-1-rich granule membrane]
RHOA [cell junction]
Rhoa [plasma membrane]
Inferred From
RHOA [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_058082.2
,
NP_001300891.1
,
NP_001300890.1
ENSEMBL
ENSMUST00000007959
,
ENSMUSP00000007959
PRO
Q9QUI0
GlyGen
Q9QUI0
MGI
1096342
PDB
7U2P
,
4F38
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8C6B2 Rtkn
2
Rtkn [cytosol]
(R-MMU-5666187)
Rtkn [cytosol]
(R-MMU-5666184)
0.702
3
UniProt:Q9BST9 RTKN
1
RTKN [cytosol]
(R-HSA-5666184)
0.589
2
UniProt:A0A0F6B1Q8 A0A0F6B1Q8
0.462
2
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